In recent years, attention of epidemiologists and clinicians is drawn to the somatic and emotional influence of meteorological factors. Aim. Meteosensitivity studying and searching predictors of its risk in patients with arterial hypertension (AH) using the original questionnaire. Material and methods. We examined 45 patients with hypertension 1—2nd degree (15 men), 57,0±11,1 years old and without coronary heart disease. Blood pressure level (BP), clinical and biochemical blood tests, blood viscosity, pulse wave velocity, indicators of the Visual Analog Scale, anxiety and depression scales were evaluated. To quantify the severity of meteosensitivity an original questionnaire with 2 scales was developed. Met1 is focus on the nature and intensity of complaints associated with meteorological factors (0—4). Met 2 is focus on natural phenomena that make the health status worse (0—3). Met = Met 1 + Met 2. Results. Meteosensitivity in hypertensive patients was usually caused by changes in atmospheric pressure and temperature (68,2% each), «magnetic storms» (63,6%), heat, and persistently high atmospheric pressure (54,5% each). The usual complaints are headaches (54,5%) and increased blood pressure (45,5%). Smoking was associated with less meteorological sensitivity (Met 38,1±18,3 for non-smokers versus 19,5±11,7 points for smokers, p=0,007). The beta-blockers taking was associated with greater meteosensitivity (43,4±17,0 vs. 28,0±17,3 points, p=0,005). In the regression model which included factors such as smoking, anxiety, heart rate, beta-blockers taking, independent predictors of high meteosensitivity were anxiety (β=0,31, p<0,05), beta-blockers taking (β=0,40, p<0,05), smoking (β=–0,30, p<0,05). The anxiety lost its prognostic value when Pulse Wave Velosity was introduced in the model. Pulse Wave Velosity was an independent negative predictor (β=–0,33, p<0,05) of high Met. Sodium and AST levels are independent predictors of high meteosensitivity in the model including SPV, uric acid levels, ALT, AST, triglycerides and sodium (β=0,63, p<0,001 and β=0,43, p<0,001, respectively). Conclusion. Meteosensitivity was observed usually in AH 1 or 2 degreein in case of weather changes, «magnetic storms», heat, high atmospheric pressure. Plasma sodium and AST levels, smoking and high Pulse Wave Velosity are independent predictors of the meteosensitivity.