The objective of the present work was to study the influence of diosmin on the characteristics of microcirculation obtained by laser Doppler flowmetry in patients presenting with sluggishly granulating wounds. They were divided into two groups comprised of 35 patients each. The main group included patients given diosmin (1 tablet daily) for 14 days in combination with traditional therapy. Patients of the control group received conventional treatment alone. Measurements of microcirculation on day 15 after the onset of therapy demonstrated high efficacy of diosmin as an agent for the correction of microcirculatory disturbances in the regions surrounding sluggishly granulating wounds. It is hypothesized that mechanism of diosmin action may be mediated through the improvement of lymphatic drainage in the affected limb.