Introduction. Currently in modern clinical practice in the general structure of surgical patients with purulent — inflammatory diseases complication’s of the soft tissues occur in 35—45% of cases. The 70—80% of these are admitted to hospitals for urgent indications. Purulent-septic infections in the world are complex and this problem is far for being solved, that is why are develop entirely new methods of treatment such as patients. One of these method — photodynamic therapy (PDT). Material and methods. Results of 80 patients treatment. In 1st group patients (general) (n1=40) on-treatment was conducted PDT. Patients in 2nd group (control group) (n2=40) received standard treatment. The average age of patients in both groups was 59.7±3.0 years (max 79 years). By gender groups were comparable in 1st group: men — 60%, women — 40%, in the 2nd group: men — 70%, women 30%. Body mass index in the 1st group was equal to 27.90±0.66 kg/m2 in the 2nd group of — 31.45±0.65 kg/m2 (p<0.05). All patients had all signs of a local surgical infection: purulent discharge from the wound, swelling, redness of the skin around the wound and the local temperature rise. Follow-up period in both groups — 25 days. Results. During the period of monitoring was not fatality in both groups. The pain management in patients of 1st group noted in a 2.1±0.9 days, in control group — 3.4±0.7 days; the skin redness around the wound is decreased in 1st group in a 2.8±0.8 days; in the control group — 4.7±0.9 days; time to stopping of exudation from the wound in the 1st and 2nd groups was 3.6±1.2 and 6.1±1.8 days, respectively. In 1st group, the duration of complete wound cleansing from necrotic masses totaled 7.3±0.8 days, the timing of the appearance of granulation — 9.4±1.2 days in the control group — 10.6±1.1 and 13.3±1.4 days, respectively. In the general group complete healing of surgical wounds was observed on the expiry of 17.8±1.2 days from starting treatment and in the control group — on the expiry of 24.1±1.0 days. The duration of hospital treatment of patients in 1st group was 7.9±0.11 per bed-day, control group — 12.7±1.2 bed-days. The total duration of inpatient and outpatient treatment of patients in the general group was 17.8±1.2 days, in the control group — 24.1±1.0 days (p<0.05). Conclusions. PDT achieves an adequate, high-performance therapy, reduce the healing time of festering postoperative wounds, improves the quality of life of patients.