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Palkina N.V.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

Ruksha T.G.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Khorzhevsky V.A.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Sergeeva E.Yu.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Fefelova Yu.A.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Gene expression profiling in melanoma diagnostics: problems and future application in clinical practice

Authors:

Palkina N.V., Ruksha T.G., Khorzhevsky V.A., Sergeeva E.Yu., Fefelova Yu.A.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2022;84(2): 64‑71

DOI: 10.17116/patol20228402164

Read: 2351 times

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Table of contents

GENE EXPRESSION PROFILING IN MELANOMA DIAGNOSTICS: PROBLEMS AND FUTURE APPLICATION IN CLINICAL PRACTICE
GENE EXPRESSION PROFILING IN MELANOMA DIAGNOSTICS: PROBLEMS AND FUTURE APPLICATION IN CLINICAL PRACTICE

To cite this article:

Palkina NV, Ruksha TG, Khorzhevsky VA, Sergeeva EYu, Fefelova YuA. Gene expression profiling in melanoma diagnostics: problems and future application in clinical practice. Russian Journal of Archive of Pathology. 2022;84(2):64‑71. (In Russ.)
https://doi.org/10.17116/patol20228402164

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Difficulties in the diagnosis and differential diagnosis of melanoma in the work of a pathologist include not only conflicting structural and morphological features, but also the insufficient effectiveness of biochemical and some molecular markers in immunohistochemical studies. The review presents modern alternative methods for diagnosing malignant tumors based on the assessment of gene expression, the performance, objectivity and reliability of the determination of which may in the future have clinical application as an addition to histopathological methods in the diagnosis and differential diagnosis of various malignant neoplasms, including melanocytic neoplasms, which is changing the paradigm of routine medical practice, introducing diagnostic tests that carry molecular information into it.

Keywords:

melanoma
diagnosis
molecular markers
gene expression profiling

Authors:

Palkina N.V.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

Ruksha T.G.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Khorzhevsky V.A.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Sergeeva E.Yu.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Fefelova Yu.A.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Health of Russia

Received:

11.11.2021

Accepted:

22.12.2021

Close metadata

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