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Ivanov A.A.

Nauchnyĭ tsentr serdechno-sosudistoĭ khirurgii im. A.N. Bakuleva RAMN, Moskva

Popova O.P.

GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdravsotsrazvitiia Rossii, Moskva

Kuznetsova A.V.

FGBU "Institut biologii razvitiia im. N.K. Kol'tsova" RAN, Moskva

Danilova T.I.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Tumor stem cells in breast cancer

Authors:

Ivanov A.A., Popova O.P., Kuznetsova A.V., Danilova T.I.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2015;77(5): 64‑67

DOI: 10.17116/patol201577564-67

Views: 1708

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To cite this article:

Ivanov AA, Popova OP, Kuznetsova AV, Danilova TI. Tumor stem cells in breast cancer. Russian Journal of Archive of Pathology. 2015;77(5):64‑67. (In Russ.)
https://doi.org/10.17116/patol201577564-67

Подписка 2025 (Russian Journal of Archive of Pathology)
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High mortality from breast cancer is associated with the high heterogeneity of tumor and the frequent recurrences of the pathological process, which are due to the presence of tumor stem cells. The review considers the biological properties of tumor stem cells, the molecular mechanisms of their regulation, interaction with the microenvironment, and their role in the heterogeneity of the morphological and clinical forms of breast cancer.

Keywords:

breast cancer
tumor heterogeneity
tumor stem cells
microenvironment

Authors:

Ivanov A.A.

Nauchnyĭ tsentr serdechno-sosudistoĭ khirurgii im. A.N. Bakuleva RAMN, Moskva

Popova O.P.

GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdravsotsrazvitiia Rossii, Moskva

Kuznetsova A.V.

FGBU "Institut biologii razvitiia im. N.K. Kol'tsova" RAN, Moskva

Danilova T.I.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

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