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Zavalishina L.É.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Petrov A.V.

State Research Institute of Highly Pure Biopreparations, Federal Biomedical Agency, St. Petersburg, Russia

Pavlenko I.A.

GBU Rostovskoĭ oblasti "Patologoanatomicheskoe biuro", Rostov-na-Donu

Gorelik M.Z.

GBUZ "Primorskoe kraevoe patologoanatomicheskoe biuro", Vladivostok

A FISH analysis in one day. Experience in evaluating HER2 gene status by means of a new HER2 IQFISH pharmDx kit

Authors:

Zavalishina L.É., Petrov A.V., Pavlenko I.A., Gorelik M.Z.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2013;75(1): 52‑53

Views: 1794

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To cite this article:

Zavalishina LÉ, Petrov AV, Pavlenko IA, Gorelik MZ. A FISH analysis in one day. Experience in evaluating HER2 gene status by means of a new HER2 IQFISH pharmDx kit. Russian Journal of Archive of Pathology. 2013;75(1):52‑53. (In Russ.)

Подписка 2025 (Russian Journal of Archive of Pathology)
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Determination of the HER2 status of tumor cells in stomach and breast cancer is a routine diagnostic method. Immunohistochemical study is sufficient for its evaluation in most cases. However, a specifying molecular genetic study using the FISH technique is performed when borderline results are obtained. The paper describes the new procedure IQFISH that allows the results to be obtained in one working day.

Keywords:

HER2 gene
breast cancer
FISH

Authors:

Zavalishina L.É.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Petrov A.V.

State Research Institute of Highly Pure Biopreparations, Federal Biomedical Agency, St. Petersburg, Russia

Pavlenko I.A.

GBU Rostovskoĭ oblasti "Patologoanatomicheskoe biuro", Rostov-na-Donu

Gorelik M.Z.

GBUZ "Primorskoe kraevoe patologoanatomicheskoe biuro", Vladivostok

List of references:

  1. Zavalishina L.E., Frank G.A. Morfologicheskoe issledovanie HER2-statusa. M.; 2010.
  2. Wolff A.C., Hammond M.E., Schwartz J.N., Hagerty K.L., Allred D.C., Cote R.J. et al. American society of clinical oncology/college of american pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J. Clin. Oncol. 2007; 25: 118-45.

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