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Udaltsov M.A.

St. Petersburg State Pediatric Medical University

Pshenisnov K.V.

Children’s Scientific Clinical Center for Infectious Diseases

Aleksandrovich Yu.S.

Children’s Scientific Clinical Center for Infectious Diseases

Kaziakhmedov V.A.

St. Petersburg State Pediatric Medical University;
Filatov Pediatric City Clinical Hospital No. 5

Ironosov V.E.

St. Petersburg State Pediatric Medical University

Epidemiology of acute poisoning in pediatric practice

Authors:

Udaltsov M.A., Pshenisnov K.V., Aleksandrovich Yu.S., Kaziakhmedov V.A., Ironosov V.E.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2024;(2): 58‑66

DOI: 10.17116/anaesthesiology202402158

Read: 2237 times

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Table of contents

EPIDEMIOLOGY OF ACUTE POISONING IN PEDIATRIC PRACTICE
EPIDEMIOLOGY OF ACUTE POISONING IN PEDIATRIC PRACTICE

To cite this article:

Udaltsov MA, Pshenisnov KV, Aleksandrovich YuS, Kaziakhmedov VA, Ironosov VE. Epidemiology of acute poisoning in pediatric practice. Russian Journal of Anesthesiology and Reanimatology. 2024;(2):58‑66. (In Russ.)
https://doi.org/10.17116/anaesthesiology202402158

 
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Abstract:

Acute poisoning is one of the most common causes of children seeking medical attention.

OBJECTIVE

To study epidemiology of acute poisoning in children of metropolis.

MATERIAL AND METHODS

We analyzed the course of acute poisoning in 17.509 children aged 0—18 years admitted to a multi-field hospital between 2010 and 2022.

RESULTS

About 1.300 children aged 0—18 years with acute poisoning admit to multi-field hospitals every year. Of these, 17.4% are patients in serious and extremely serious state requiring intensive care. Children with acute poisoning comprise 25% of total number of ICU patients. The most common toxicants are ethanol, psychotropic and cardiovascular agents. Severe poisoning is common in adolescents. The main toxicants are methadone (24%), ethanol (22%), other depleting agents (24%) and psychodisleptics (18%). Mechanical ventilation is necessary in 50% of children (mean duration 22 [8—53] hours). Regardless of toxicant, fluid load on the first day of intensive care comprised 143% [124—172] of age-related physiologic fluid demand. Complete recovery took place in 98% of cases. Three (0.1%) patients died.

CONCLUSION

Acute poisoning in children requiring intensive care is most often due to intake of methadone and psychotropic drugs in adolescence (17.4% of all admissions in toxicological profile).

Keywords:

poisoning
intensive care
outcome
epidemiology
pediatrics

Authors:

Udaltsov M.A.

St. Petersburg State Pediatric Medical University

Pshenisnov K.V.

Children’s Scientific Clinical Center for Infectious Diseases

Aleksandrovich Yu.S.

Children’s Scientific Clinical Center for Infectious Diseases

Kaziakhmedov V.A.

St. Petersburg State Pediatric Medical University;
Filatov Pediatric City Clinical Hospital No. 5

Ironosov V.E.

St. Petersburg State Pediatric Medical University

Received:

12.11.2023

Accepted:

09.01.2024

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