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Bykova K.M.

Almazov National Medical Research Center

Blinov S.A.

Children’s Clinical Hospital

Tonkonogov D.A.

Children’s Clinical Hospital

Kirbyatyeva M.A.

Children’s Clinical Hospital

Zakharenko N.V.

Children’s Clinical Hospital

Manenok Yu.N.

Children’s Clinical Hospital

Kraynova M.L.

Children’s Clinical Hospital

Martinen M.S.

Children’s Clinical Hospital

Protasov A.S.

Children’s Clinical Hospital

Potemkina E.G.

Almazov National Medical Research Centre, Polenov Neurosurgery Research Institute

Savvina I.A.

Polenov Neurosurgical Institute;
Mechnikov North-West State Medical University

Treatment of a teenager with fall from height and high-voltage electrical injury complicated by sepsis-associated encephalopathy

Authors:

Bykova K.M., Blinov S.A., Tonkonogov D.A., Kirbyatyeva M.A., Zakharenko N.V., Manenok Yu.N., Kraynova M.L., Martinen M.S., Protasov A.S., Potemkina E.G., Savvina I.A.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2024;(1): 64‑73

DOI: 10.17116/anaesthesiology202401164

Views: 1141

Downloaded: 33

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Table of contents

TREATMENT OF A TEENAGER WITH FALL FROM HEIGHT AND HIGH-VOLTAGE ELECTRICAL INJURY COMPLICATED BY SEPSIS-ASSOCIATED ENCEPHALOPATHY
TREATMENT OF A TEENAGER WITH FALL FROM HEIGHT AND HIGH-VOLTAGE ELECTRICAL INJURY COMPLICATED BY SEPSIS-ASSOCIATED ENCEPHALOPATHY

To cite this article:

Bykova KM, Blinov SA, Tonkonogov DA, et al. . Treatment of a teenager with fall from height and high-voltage electrical injury complicated by sepsis-associated encephalopathy. Russian Journal of Anesthesiology and Reanimatology. 2024;(1):64‑73. (In Russ.)
https://doi.org/10.17116/anaesthesiology202401164

 
Подписка 2025-2 (АиР)
МСФ на ЯМ
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We report successful treatment of a teenager with acute multicomponent cerebral damage (fall from height injury, high-voltage electrical injury, sepsis-associated encephalopathy). The issues of diagnosis and pathogenetic treatment, as well as methodology of neurovegetative stabilization are discussed. The last method of antinociceptive protection integrates the patient’s sanogenetic potential that ensured favorable outcome and minimal disability.

Keywords:

fall from height injury
high-voltage electrical injury
sepsis-associated encephalopathy
neurovegetative stabilization
neuroprotective therapy

Authors:

Bykova K.M.

Almazov National Medical Research Center

Blinov S.A.

Children’s Clinical Hospital

Tonkonogov D.A.

Children’s Clinical Hospital

Kirbyatyeva M.A.

Children’s Clinical Hospital

Zakharenko N.V.

Children’s Clinical Hospital

Manenok Yu.N.

Children’s Clinical Hospital

Kraynova M.L.

Children’s Clinical Hospital

Martinen M.S.

Children’s Clinical Hospital

Protasov A.S.

Children’s Clinical Hospital

Potemkina E.G.

Almazov National Medical Research Centre, Polenov Neurosurgery Research Institute

Savvina I.A.

Polenov Neurosurgical Institute;
Mechnikov North-West State Medical University

Received:

13.08.2023

Accepted:

16.09.2023

List of references:

  1. Sepsis u detej. Klinicheskie rekomendatsii. 2021. Accessed November 30, 2023. (In Russ). https://babyanesthesia.ru/wp-content/uploads/2021/04/%D0%9A%D0%A0_%D0%A1%D0%B5%D0%BF%D1%81%D0%B8%D1%81_%2013.04.2021%E2%80%9111.pdf?ysclid=lpnrn60rd7849245975
  2. Gürünlüoğlu K, Demircan M, Taşçi A, Üremiş MM, Türköz Y, Gözükara Bağ H. Effects of high-voltage electrical burns and other burns on levels of serum oxidative stress and telomerase in children. Burns. 2018;44(8):2034-2041. https://doi.org/10.1016/j.burns.2018.07.001
  3. Zhao L, Li Y, Wang Y, Ge Z, Zhu H, Zhou X, Li Y. Non-hepatic Hyperammonemia: A Potential Therapeutic Target for Sepsis-associated Encephalopathy. CNS and Neurological Disorders Drug Targets. 2022;21(9):738-751.  https://doi.org/10.2174/1871527321666211221161534
  4. Beloborodova NV, Ostrova IV. Sepsis-associated encephalopathy. General Reanimatology. 2018;13:121-139. (In Russ.). https://doi.org/10.15360/1813-9779-2017-5-121-139
  5. Savvina IA, Zabrodskaya YM, Sebelev KI, Petrova AO, Bodareva NV. Sepian encephalopathy: pathophysiology, pathomorphology, clinical syndromes and therapeutic tactics. Nejrokhirurgiya i nevrologiya detskogo vozrasta. 2017;4(17):20-33. (In Russ.).
  6. Piazza O, Cotena S, De Robertis E, Caranci F, Tufano R. Sepsis associated encephalopathy studied by MRI and cerebral spinal fluid S100B measurement. Neurochemical Research. 2009;34(7):1289-1292. https://doi.org/10.1007/s11064-008-9907-2
  7. Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: A prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine. 2015;41(4):686-694.  https://doi.org/10.1007/s00134-015-3709-1
  8. Kondratyev AN, Tsentsiper LM, Kondratyeva EA, Nazarov RV. Neurovegetative stabilization as a pathogenetic therapy for brain damage. Anesteziologiya i Reanimatologiya. 2014;1:82-84. (In Russ.).

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