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Sokolov D.A.

Yaroslavl State Medical University;
Regional Clinical Hospital

Zhbannikov P.S.

Yaroslavl State Medical University

Ganert A.N.

Yaroslavl State Medical University;
Regional Clinical Hospital

Larionov S.V.

Yaroslavl State Medical University

Lyuboshevskiy P.A.

Yaroslavl State Medical University;
Regional Clinical Hospital

Accuracy of predictors of perioperative cardiovascular complications in onco-surgery

Authors:

Sokolov D.A., Zhbannikov P.S., Ganert A.N., Larionov S.V., Lyuboshevskiy P.A.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2023;(3): 37‑44

DOI: 10.17116/anaesthesiology202303137

Read: 3609 times

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Table of contents

ACCURACY OF PREDICTORS OF PERIOPERATIVE CARDIOVASCULAR COMPLICATIONS IN ONCO-SURGERY
ACCURACY OF PREDICTORS OF PERIOPERATIVE CARDIOVASCULAR COMPLICATIONS IN ONCO-SURGERY

To cite this article:

Sokolov DA, Zhbannikov PS, Ganert AN, Larionov SV, Lyuboshevskiy PA. Accuracy of predictors of perioperative cardiovascular complications in onco-surgery. Russian Journal of Anesthesiology and Reanimatology. 2023;(3):37‑44. (In Russ., In Engl.)
https://doi.org/10.17116/anaesthesiology202303137

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Abstract:

OBJECTIVE

To assess the informative value of predictors of potential perioperative cardiovascular complications (CVC) in oncological abdominal surgery.

MATERIAL AND METHODS

We examined 114 patients aged 67 [61—72] years who underwent elective oncological surgery. Perioperative CVCs were recorded. We analyzed prognostic significance of patient characteristics (including calculated cardiac risk indices — CRI) and biomarkers in relation to CVC.

RESULTS

Perioperative CVCs occurred in 13 (11.4%) patients. According to logistic regression, predictors of perioperative CVC were CRI Khoronenko (p=0.0001) and CRI MICA (p=0.0023). AUC for these indices was 0.774 and 0.798, respectively. Preoperative serum NT-proBNP demonstrated higher quality of predictive model: OR 1.0112; 95% CI 1.0054—1.0170; p=0.0001; AUC 0.91. Serum biomarker >257 pg/ml discriminated patients with perioperative CVC with a sensitivity of 84.62% and specificity of 86.17%.

CONCLUSION

Preoperative serum NT-proBNP >257 pg/mL with sensitivity and specificity >80% is a predictor of perioperative CVC after abdominal oncological surgery. Assessment of this marker is appropriate in patients with high and intermediate cardiac risk.

Keywords:

predictors of complications
non-cardiac surgery
perioperative cardiovascular complications
cardiac complications
cardiac risk indices
natriuretic peptides
NT-proBNP
troponin
biomarkers
oncology

Authors:

Sokolov D.A.

Yaroslavl State Medical University;
Regional Clinical Hospital

Zhbannikov P.S.

Yaroslavl State Medical University

Ganert A.N.

Yaroslavl State Medical University;
Regional Clinical Hospital

Larionov S.V.

Yaroslavl State Medical University

Lyuboshevskiy P.A.

Yaroslavl State Medical University;
Regional Clinical Hospital

Received:

07.02.2023

Accepted:

17.03.2023

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