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Bofanova N.S.

Penza State University

Khanfar Ya.A.

Penza State University

Influence of gut microbiota on chronic pain syndrome

Authors:

Bofanova N.S., Khanfar Ya.A.

More about the authors

Journal: Russian Journal of Pain. 2023;21(2): 50‑56

DOI: 10.17116/pain20232102150

Views: 2979

Downloaded: 100

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Table of contents

INFLUENCE OF GUT MICROBIOTA ON CHRONIC PAIN SYNDROME
INFLUENCE OF GUT MICROBIOTA ON CHRONIC PAIN SYNDROME

To cite this article:

Bofanova NS, Khanfar YaA. Influence of gut microbiota on chronic pain syndrome. Russian Journal of Pain. 2023;21(2):50‑56. (In Russ.)
https://doi.org/10.17116/pain20232102150

 
Подписка 2025-2 (Russian Journal of Pain)
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OBJECTIVE

To study the influence of gut microbiota on formation of chronic pain syndrome.

MATERIAL AND METHODS

We analyzed available literature data in the Scopus, Web of Science, PubMed and Embase databases using certain keywords (gut-brain axis, intestinal microbiome, chronic pain).

RESULTS

Modern available data devoted to relationship between intestinal microbiota, activity of central nervous system and formation of chronic pain were analyzed. The modern concept of “intestinal microbiome-gut-brain axis” was described. We considered the mechanisms of “intestinal microbiome-gut-brain axis” and the main neurotransmitters. Information on the influence of intestinal microbiota in formation of pain syndrome was obtained.

CONCLUSION

The theory of influence of gut microbiota on chronic pain syndrome allows development of new approaches to the treatment of chronic pain syndromes. The last ones are based on current knowledge about intestinal microbiota and its effect on central nervous system.

Keywords:

gut-brain axis
intestinal microbiome
chronic pain

Authors:

Bofanova N.S.

Penza State University

Khanfar Ya.A.

Penza State University

Received:

25.10.2022

Accepted:

10.11.2022

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