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Toropkina Yu.E.

Rostov State Medical University

Romanenko Yu.V.

Rostov State Medical University

Naletova D.A.

Rostov State Medical University

Alekseev V.V.

Rostov State Medical University

Ovsyannikov V.G.

Rostov State Medical University

Alekseeva N.S.

Rostov State Medical University

Krivokhlyabov I.P.

Rostov State Medical University

Popivnenko M.D.

Rostov State Medical University

Laboratory models of neuropathic pain: review and practical recommendations

Authors:

Toropkina Yu.E., Romanenko Yu.V., Naletova D.A., Alekseev V.V., Ovsyannikov V.G., Alekseeva N.S., Krivokhlyabov I.P., Popivnenko M.D.

More about the authors

Journal: Russian Journal of Pain. 2023;21(2): 38‑49

DOI: 10.17116/pain20232102138

Views: 2254

Downloaded: 95

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Table of contents

LABORATORY MODELS OF NEUROPATHIC PAIN: REVIEW AND PRACTICAL RECOMMENDATIONS
LABORATORY MODELS OF NEUROPATHIC PAIN: REVIEW AND PRACTICAL RECOMMENDATIONS

To cite this article:

Toropkina YuE, Romanenko YuV, Naletova DA, et al. . Laboratory models of neuropathic pain: review and practical recommendations. Russian Journal of Pain. 2023;21(2):38‑49. (In Russ.)
https://doi.org/10.17116/pain20232102138

Подписка 2025-2 (Russian Journal of Pain)
МСФ на ЯМ
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This review is devoted to modern models of neuropathic pain in laboratory animals that can be optimal method for research. The key features of the article are separation of models depending on etiological characteristics, description of surgical models with analysis of their advantages and disadvantages, characteristics of methods for assessing severity of pain syndrome and focusing on importance of certain conditions for keeping animals involved in experiments on neuropathic pain. Combination of these data will allow choosing the most appropriate model of neuropathic pain depending on the objectives of research. Formation and evaluation of neuropathic pain will increase the effectiveness of surgical interventions. Modification of neuropathic pain model is described in the article. This modification is based on analysis of modern techniques and own experience and provided favorable results in various studies. In addition, scales for neuropathic pain syndrome modified by the authors will allow assessing its severity.

Keywords:

neuropathic pain
experimental model
pain assessment
laboratory animals

Authors:

Toropkina Yu.E.

Rostov State Medical University

Romanenko Yu.V.

Rostov State Medical University

Naletova D.A.

Rostov State Medical University

Alekseev V.V.

Rostov State Medical University

Ovsyannikov V.G.

Rostov State Medical University

Alekseeva N.S.

Rostov State Medical University

Krivokhlyabov I.P.

Rostov State Medical University

Popivnenko M.D.

Rostov State Medical University

Received:

25.01.2023

Accepted:

05.04.2023

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