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Postoperative complications following resection of extramedullary tumors of the craniovertebral junction region

Postoperative complications following resection of extramedullary tumors of the craniovertebral junction region

Authors:
Лабзина Е.Е.,
Кубецкий Ю.Е.,
Косимшоев М.А.,
Рзаев Д.А.,
Степаненко В.В.

Журнал: Вопросы нейрохирургии имени Н.Н. Бурденко. 2026;90(1):14-20.

DOI: 10.17116/neiro20269001114

Read: 1789 раз

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Abstract

Surgical treatment of extramedullary tumors of the craniovertebral junction (CVJ) remains a difficult task due to adjacent important neurovascular structures. International data indicate high incidence of postoperative complications following surgical intervention alone.

OBJECTIVE. T

O analyze postoperative complications following resection of CVJ extramedullary tumors.

MATERIAL AND METHODS

A retrospective study of treatment outcomes in 64 patients with CVJ tumors was performed between 2013 and 2024. Neurological status in pre- and postoperative period was assessed depending on location, histological variant of tumor and surgical approach. Surgical, neurological and somatic complications were specified.

RESULTS

Postoperative complications occurred in 23 (38%) patients. For meningiomas, complications occurred in 38.4% of cases, for schwannomas — in 23.5%, for neurofibromas — in 57.1% of cases. Lateral and median approaches had similar complication rates (35.7% and 33.3%, respectively). Surgical complications occurred in 11 (21.8%) patients, and infectious complications were the most common (meningitis in 6 (9.3%) patients). Neurological complications were detected in 13 (20.3%) patients, and dysfunction of bulbar nerves prevailed (7 (10.9%) patients). Somatic postoperative complications occurred in 8 (12.5%) patients, fatal outcomes — in 1 (1.5%) case.

CONCLUSION

Our results demonstrate high incidence of postoperative complications after surgical treatment of extramedullary CVJ tumors.

Keywords

  • postoperative complications
  • craniovertebral junction
  • craniovertebral meningiomas

Дата поступления: 05.05.2025

Дата принятия в печать: 26.11.2025

Дата публикации: 11.02.2026

References
  1. Shimansky VN, Sultanov RA, Tanyashin SV, Golanov AV, Galkin MV, Karnaukhov VV, Danilov GV, Strunina YuV. Surgical and combined treatment of patients with craniovertebral junction meningioma: a single-center retrospective study of 196 cases. Burdenko’s Journal of Neurosurgery. 2023;87(2):22-29. (In Russ., In Engl.). https://doi.org/10.17116/neiro20238702122
  2. Palmisciano P, Ferini G, Watanabe G, Conching A, Ogasawara C, Scalia G, Bin-Alamer O, Haider AS, Passanisi M, Maugeri R, Hoz SS, Baldoncini M, Campero A, Salvati M, Cohen-Gadol AA, Umana GE. Surgical Management of Craniovertebral Junction Schwannomas: A Systematic Review. Current Oncology. 2022;29(7):4842-4855. https://doi.org/10.3390/curroncol29070384
  3. Kaprovoy SV, Konovalov NA, Onoprienko RA, Strunina YuV, Shmelev ND. Minimally invasive surgical treatment of extramedullary tumors at the level of craniovertebral junction: experience of the Burdenko Neurosurgical Center. Burdenko’s Journal of Neurosurgery. 2024;88(2):39-46. (In Russ., In Engl.). https://doi.org/10.17116/neiro20248802139
  4. Bruneau M, George B. Foramen magnum meningiomas: detailed surgical approaches and technical aspects at Lariboisière Hospital and review of the literature. Neurosurgical review. 2008;31(1):19-32; discussion 32-33. https://doi.org/10.1007/s10143-007-0097-1
  5. Fatima N, Shin JH, Curry WT, Chang SD, Meola A. Microsurgical resection of foramen magnum meningioma: multi-institutional retrospective case series and proposed surgical risk scoring system. Journal of Neuro-Oncology. 2021;153(2):331-342. https://doi.org/10.1007/s11060-021-03773-z
  6. Paun L, Gondar R, Borrelli P, Meling TR. Foramen magnum meningiomas: a systematic review and meta-analysis. Neurosurgical review. 2021;44(5):2583-2596. https://doi.org/10.1007/s10143-021-01478-5
  7. Wu P, Guan Y, Wang M, Zhang L, Zhao D, Cui X, Liu J, Qiu B, Tao J, Wang Y, Ou S. Classification and microsurgical treatment of foramen magnum meningioma. Chinese Neurosurgical Journal. 2023;9(1):3. https://doi.org/10.1186/s41016-022-00315-y
  8. Stepanenko VV, Shamanin VA, Trashin AV, Shulev YuA, Khalepa RV, Kosimshoev MA, Kubetsky YuE, Rzaev DA. Craniovertebral intradural meningiomas: analysis of postoperative outcomes (a retrospective two-center study). Burdenko’s Journal of Neurosurgery. 2024;88(6):23-30. (In Russ., In Engl.). https://doi.org/10.17116/neiro20248806123
  9. Kaprovoy SV, Konovalov NA, Onoprienko RA, Stepanov IA. Benign extramedullary spinal cord tumors at the level of craniovertebral junction: a systematic review. Burdenko’s Journal of Neurosurgery. 2022;86(4):96-103. (In Russ., In Engl.). https://doi.org/10.17116/neiro20228604196
  10. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Annals of Surgery. 2004;240(2):205-13. https://doi.org/10.1097/01.sla.0000133083.54934.ae
  11. Song G, Cheng Y, Bai X, Ren J, Li M, Meng G, Tang J, Liang J, Guo H, Chen G, Bao Y, Xiao X. Technique Nuances for Functional Preservation of Lower Cranial Nerves during Surgical Management of Ventral Foramen Magnum Meningiomas Via a Dorsal Lateral Approach. World Neurosurgery. 2021;146:e1242-e1254. https://doi.org/10.1016/j.wneu.2020.11.140
  12. Rudenko PG, Shnyakin PG, Narkevich AN, Abakumova TA, Tyumentsev NV, Fayzova MN. Peculiarities of cerebral blood flow and vascular reactivity in patients with large and giant tumors of the cerebello-pontine angle. Russian Journal of Neurosurgery. 2024;26(3):31-42. https://doi.org/10.17650/1683-3295-2024-26-3-31-42
  13. Spatenkova V, Bradac O, Mareckova Z, Suchomel P, Hradil J, Kuriscak E, Halacova M. Incidence of surgical site infections after cervical spine surgery: results of a single-center cohort study adhering to multimodal preventive wound control protocol. European Journal of Orthopaedic Surgery and Traumatology. 2023;33(5):1997-2004. https://doi.org/10.1007/s00590-022-03379-9
  14. Kim JY, Oh BH, Kim IS, Hong JT, Sung JH, Lee HJ. The safety and effectiveness of lumbar drainage for cerebrospinal fluid leakage after spinal surgery. Neurochirurgie. 2023;69(6):101501. https://doi.org/10.1016/j.neuchi.2023.101501
  15. Vastani A, Baig Mirza A, Ali F, Iqbal A, Sharma C, Khizar Khoja A, Vaqas B, Lavrador JP, Pollock J. Cerebrospinal fluid diversion prior to posterior fossa tumor resection in adults: A systematic review. Neuro-Oncology Practice. 2024;11(6):703-712. https://doi.org/10.1093/nop/npae055
  16. Lee KS, Borbas B, Plaha P, Ashkan K, Jenkinson MD, Price SJ. Incidence and Risk Factors of Surgical Site Infection After Cranial Surgery for Patients with Brain Tumors: A Systematic Review and Meta-analysis. World Neurosurgery. 2024;185:e800-e819. https://doi.org/10.1016/j.wneu.2024.02.133
  17. Gu Y, Zhang Y, Zeng M, Han Y, Long X. A retrospective observational study of risk factors for postoperative meningitis following resection of meningioma. Journal of International Medical Research. 2025;53(3):3000605251327527. https://doi.org/10.1177/03000605251327527
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