The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Gumin I.S.

Federal Center of Brain and Neurotechnologies

Malykhina E.A.

Pirogov Russian National Research Medical University;
Federal Center for Brain and Neurotechnologies

Dzhafarov V.M.

Federal Neurosurgery Center

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Senko I.V.

Sklifosovsky Research Institute for Emergency Care;
Federal Center for Brain and Neurotechnologies

Dolgushin M.B.

Federal Center of Brain and Neurotechnologies of the Federal Medical Biological Agency

First experience of thalamotomy by focused ultrasound under MR-guided navigation in the treatment of tremor. Neuroimaging follow-up. Case report and literature review

Authors:

Gumin I.S., Malykhina E.A., Dzhafarov V.M., Katunina E.A., Senko I.V., Dolgushin M.B.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2022;86(5): 81‑88

DOI: 10.17116/neiro20228605181

Views: 3784

Downloaded: 143

Download PDF (RU)
Download PDF
Contact the author
Table of contents

FIRST EXPERIENCE OF THALAMOTOMY BY FOCUSED ULTRASOUND UNDER MR-GUIDED NAVIGATION IN THE TREATMENT OF TREMOR. NEUROIMAGING FOLLOW-UP. CASE REPORT AND LITERATURE REVIEW
FIRST EXPERIENCE OF THALAMOTOMY BY FOCUSED ULTRASOUND UNDER MR-GUIDED NAVIGATION IN THE TREATMENT OF TREMOR. NEUROIMAGING FOLLOW-UP. CASE REPORT AND LITERATURE REVIEW

To cite this article:

Gumin IS, Malykhina EA, Dzhafarov VM, Katunina EA, Senko IV, Dolgushin MB. First experience of thalamotomy by focused ultrasound under MR-guided navigation in the treatment of tremor. Neuroimaging follow-up. Case report and literature review. Burdenko's Journal of Neurosurgery. 2022;86(5):81‑88. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20228605181

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)
 
МСФ на ЯМ
Close metadata
Recommended articles:
Growing skull fracture of the orbi­tal roof: case report and lite­rature review. Burdenko's Journal of Neurosurgery. 2024;(5):77-86
Analysis of state guarantees for MRI in acco­rdance with procedures for medi­cal care approved by the Mini­stry of Health. Medi­cal Technologies. Asse­ssment and Choice. 2024;(2):69-77
The asso­ciation of single-nucleotide poly­morphism rs6265 of the brain-derived neurotrophic factor gene with clinical features in Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(7):82-88
The central vein sign in the differential diagnosis of multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(7-2):58-65
Rational combination of neo-collagenesis stimulation with high-intensity focu­sed ultrasound (HIFU) and inje­ctable poly-L-lactic acid (PLLA) in different morphotypes of aging: details matter. Russian Journal of Clinical Dermatology and Vene­reology. 2024;(4):475-487
Progressive multifocal leukoencephalopathy in HIV-positive indi­viduals. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8):39-46
Immu­nological and neuroanatomic markers of the clinical dyna­mics of MCI and pre-MCI. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8):81-91
Sarcopenia as a non-motor symptom of Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):15-22
Asso­ciation of inflammation and chro­nic fati­gue syndrome in patients with Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):79-87
Electric acti­vity of the brain at early and late clinical stages of expe­rimental mode­ling of Parkinson’s disease, an impact of hema­ntane. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):129-134

The authors describe dynamic MRI and clinical data after non-invasive treatment of tremor in the upper extremity. Thalamotomy by high-intensity focused ultrasound under MR-guided navigation was performed. A 57-year-old patient with Parkinson’s disease underwent treatment with focused ultrasound. MRI of the brain was performed 1 and 48 hours, 47 days, 3 and 6 months later. Features of natural course of focal brain changes after treatment, data of MR tractography necessary for correction of target zone are described. The authors conclude that MR changes are characterized by presence of a focus in the area of focused exposure. Peak severity is observed on the second day after procedure with subsequent regression. MR-based analysis of predictors is promising to forecast treatment outcomes.

Keywords:

focused ultrasound
tremor
Parkinson’s disease
tractography
MRI
FUS
thalamotomy
HIFU

Authors:

Gumin I.S.

Federal Center of Brain and Neurotechnologies

Malykhina E.A.

Pirogov Russian National Research Medical University;
Federal Center for Brain and Neurotechnologies

Dzhafarov V.M.

Federal Neurosurgery Center

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Senko I.V.

Sklifosovsky Research Institute for Emergency Care;
Federal Center for Brain and Neurotechnologies

Dolgushin M.B.

Federal Center of Brain and Neurotechnologies of the Federal Medical Biological Agency

Received:

18.04.2022

Accepted:

19.08.2022

List of references:

  1. Shneider SA, Deuschl G. The Treatment of Tremor. Neurotherapeutics. 2014;11:128-138.  https://doi.org/10.1007/s13311-013-0230-5
  2. Tokarev AS, Rozhnova EN, Sinkin MV, Tomskiy AA, Rak VA, Stepanov VN, Viktorova OA. Surgical treatments for Parkinson’s disease. Rossijskij nevrologicheskij zhurnal. 2021;26(4):4-14. (In Russ.). https://doi.org/10.30629/2658-7947-2021-26-4-4-14
  3. Quadri SA, Waqas M, Khan I, Khan MA, Suriya SS, Farooqui M, Fiani B. High-intensity focused ultrasound: Past, present, and future in neurosurgery. Neurosurgical Focus. 2018;44(2):E16.  https://doi.org/10.3171/2017.11.FOCUS17610
  4. Krishna V, Sammartino F, Rezai AA. Review of the Current Therapies, Challenges, and Future Directions of Transcranial Focused Ultrasound Technology. JAMA Neurology. 2018;75(2):246-254.  https://doi.org/10.1001/jamaneurol.2017.3129
  5. Magara A, Bühler R, Moser D, Kowalski M, Pourtehrani P, Jeanmonod D. First experience with MR-guided focused ultrasound in the treatment of Parkinson’s disease. Journal of Therapeutic Ultrasound. 2014;2:11.  https://doi.org/10.1186/2050-5736-2-11
  6. Goldman MS, Kelly PJ. Stereotactic Thalamotomy for Medically Intractable Essential Tremor. Stereotactic and Functional Neurosurgery. 1992;58:22-25.  https://doi.org/10.1159/000098966
  7. Martin E, Jeanmonod D, Morel A, Zadicario E, Werner B. High-intensity focused ultrasound for noninvasive functional neurosurgery. Annals of Neurology. 2009;66(6):858-861.  https://doi.org/10.1002/ana.21801
  8. Elias WJ, Lipsman N, Ondo WG, Ghanouni P, Kim YG, Lee W, Schwartz M, Hynynen K, Lozano AM, Shah BB, Huss D, Dallapiazza RF, Gwinn R, Witt J, Ro S, Eisenberg HM, Fishman PS, Gandhi D, Halpern CH, Chuang R, Butts Pauly K, Tierney TS, Hayes MT, Cosgrove GR, Yamaguchi T, Abe K, Taira T, Chang JW. A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor. The New England Journal of Medicine. 2016;375(8):730-739.  https://doi.org/10.1056/NEJMoa1600159
  9. Chang JW, Park CK, Lipsman N, Schwartz ML, Ghanouni P, Henderson JM, Gwinn R, Witt J, Tierney TS, Cosgrove GR, Shah BB, Abe K, Taira T, Lozano AM, Eisenberg HM, Fishman PS, Elias WJ. A prospective trial of magnetic resonance-guided focused ultrasound thalamotomy for essential tremor: Results at the 2-year follow-up. Annals of Neurology. 2018;83(1):107-114.  https://doi.org/10.1002/ana.25126
  10. Tian Q, Wintermark M, Jeffrey Elias W, Ghanouni P, Halpern CH, Henderson JM, Huss DS, Goubran M, Thaler C, Airan R, Zeineh M, Pauly KB, McNab JA. Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor. NeuroImage: Clinical. 2018;19:572-580.  https://doi.org/10.1016/j.nicl.2018.05.010
  11. Zur G, Lesman-Segev OH, Schlesinger I, Goldsher D, Sinai A, Zaaroor M, Assaf Y, Eran A, Kahn I. Tremor Relief and Structural Integrity after MRI-guided Focused US Thalamotomy in Tremor Disorders. Radiology. 2020;294:676-685.  https://doi.org/10.1148/radiol.2019191624
  12. Keil VC, Borger V, Purrer V, Groetz SF, Scheef L, Boecker H, Schild HH, Kindler C, Schmitt A, Solymosi L, Wüllner U, Pieper CC. MRI follow-up after magnetic resonance-guided focused ultrasound for non-invasive thalamotomy: the neuroradiologist’s perspective. Neuroradiology. 2020;62(9):1111-1122. https://doi.org/10.1007/s00234-020-02433-9
  13. Fasano A, De Vloo P, Llinas M, Hlasny E, Kucharczyk W, Hamani C, Lozano AM. Magnetic Resonance Imaging-Guided Focused Ultrasound Thalamotomy in Parkinson Tremor: Reoperation After Benefit Decay. Movement Disorders. 2018;33(5):848-849.  https://doi.org/10.1002/mds.27348
  14. Fasano A, Llinas M, Munhoz RP, Hlasny E, Kucharczyk W, Lozano AM. MRI-guided focused ultrasound thalamotomy in non-ET tremor syndromes. Neurology. 2017;89(9):771-775.  https://doi.org/10.1212/WNL.0000000000004268
  15. Nguyen HS, Milbach N, Hurrell SL, Cochran E, Connelly J, Bovi JA, Schultz CJ, Mueller WM, Rand SD, Schmainda KM, LaViolette PS. Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma. American Journal of Neuroradiology. 2016;37(12):2201-2208. https://doi.org/10.3174/ajnr.A4898
  16. Zakhari N, Taccone MS, Torres C, Chakraborty S, Sinclair J, Woulfe J, Jansen GH, Nguyen TB. Diagnostic Accuracy of Centrally Restricted Diffusion in the Differentiation of Treatment-Related Necrosis from Tumor Recurrence in High-Grade Gliomas. American Journal of Neuroradiology. 2018;39(2):260-264.  https://doi.org/10.3174/ajnr.A5485
  17. Bond AE, Shah BB, Huss DS, Dallapiazza RF, Warren A, Harrison MB, Sperling SA, Wang X-Q, Gwinn R, Witt J, Ro S, Elias WJ. Safety and Efficacy of Focused Ultrasound Thalamotomy for Patients With Medication-Refractory, Tremor-Dominant Parkinson Disease. A Randomized Clinical Trial. JAMA Neurology. 2017;74(12):1412-1418. https://doi.org/10.1001/jamaneurol.2017.3098

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.