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Gumin I.S.

Federal Center of Brain and Neurotechnologies

Malykhina E.A.

Pirogov Russian National Research Medical University;
Federal Center for Brain and Neurotechnologies

Dzhafarov V.M.

Federal Neurosurgery Center

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Senko I.V.

Sklifosovsky Research Institute for Emergency Care;
Federal Center for Brain and Neurotechnologies

Dolgushin M.B.

Federal Center of Brain and Neurotechnologies of the Federal Medical Biological Agency

First experience of thalamotomy by focused ultrasound under MR-guided navigation in the treatment of tremor. Neuroimaging follow-up. Case report and literature review

Authors:

Gumin I.S., Malykhina E.A., Dzhafarov V.M., Katunina E.A., Senko I.V., Dolgushin M.B.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2022;86(5): 81‑88

DOI: 10.17116/neiro20228605181

Read: 4468 times

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Table of contents

FIRST EXPERIENCE OF THALAMOTOMY BY FOCUSED ULTRASOUND UNDER MR-GUIDED NAVIGATION IN THE TREATMENT OF TREMOR. NEUROIMAGING FOLLOW-UP. CASE REPORT AND LITERATURE REVIEW
FIRST EXPERIENCE OF THALAMOTOMY BY FOCUSED ULTRASOUND UNDER MR-GUIDED NAVIGATION IN THE TREATMENT OF TREMOR. NEUROIMAGING FOLLOW-UP. CASE REPORT AND LITERATURE REVIEW

To cite this article:

Gumin IS, Malykhina EA, Dzhafarov VM, Katunina EA, Senko IV, Dolgushin MB. First experience of thalamotomy by focused ultrasound under MR-guided navigation in the treatment of tremor. Neuroimaging follow-up. Case report and literature review. Burdenko's Journal of Neurosurgery. 2022;86(5):81‑88. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20228605181

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
 
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Использование инфографики авторами научных работ
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Abstract:

The authors describe dynamic MRI and clinical data after non-invasive treatment of tremor in the upper extremity. Thalamotomy by high-intensity focused ultrasound under MR-guided navigation was performed. A 57-year-old patient with Parkinson’s disease underwent treatment with focused ultrasound. MRI of the brain was performed 1 and 48 hours, 47 days, 3 and 6 months later. Features of natural course of focal brain changes after treatment, data of MR tractography necessary for correction of target zone are described. The authors conclude that MR changes are characterized by presence of a focus in the area of focused exposure. Peak severity is observed on the second day after procedure with subsequent regression. MR-based analysis of predictors is promising to forecast treatment outcomes.

Keywords:

focused ultrasound
tremor
Parkinson’s disease
tractography
MRI
FUS
thalamotomy
HIFU

Authors:

Gumin I.S.

Federal Center of Brain and Neurotechnologies

Malykhina E.A.

Pirogov Russian National Research Medical University;
Federal Center for Brain and Neurotechnologies

Dzhafarov V.M.

Federal Neurosurgery Center

Katunina E.A.

Federal Center of Brain and Neurotechnologies;
Pirogov Russian National Research Medical University

Senko I.V.

Sklifosovsky Research Institute for Emergency Care;
Federal Center for Brain and Neurotechnologies

Dolgushin M.B.

Federal Center of Brain and Neurotechnologies of the Federal Medical Biological Agency

Received:

18.04.2022

Accepted:

19.08.2022

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References:

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  2. Tokarev AS, Rozhnova EN, Sinkin MV, Tomskiy AA, Rak VA, Stepanov VN, Viktorova OA. Surgical treatments for Parkinson’s disease. Rossijskij nevrologicheskij zhurnal. 2021;26(4):4-14. (In Russ.). https://doi.org/10.30629/2658-7947-2021-26-4-4-14
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