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Alpha-lipoic acid in the treatment of diabetic polyneuropathy

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(1): 103‑109

DOI: 10.17116/jnevro201811811103-109

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ALPHA-LIPOIC ACID IN THE TREATMENT OF DIABETIC POLYNEUROPATHY
ALPHA-LIPOIC ACID IN THE TREATMENT OF DIABETIC POLYNEUROPATHY

To cite this article:

Alpha-lipoic acid in the treatment of diabetic polyneuropathy. S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(1):103‑109. (In Russ.)
https://doi.org/10.17116/jnevro201811811103-109

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment.

Keywords:

diabetes mellitus
diabetic neuropathies
oxidative stress
endothelial dysfunction
alpha-lipoic acid

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References:

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