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Alekseev V.V.

Kafedra voenno-morskoĭ i gospital'noĭ khirurgii Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Flupirtin (katadolon): a nonstandard action on pain transmission

Authors:

Alekseev V.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(4): 101‑104

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FLUPIRTIN (KATADOLON): A NONSTANDARD ACTION ON PAIN TRANSMISSION
FLUPIRTIN (KATADOLON): A NONSTANDARD ACTION ON PAIN TRANSMISSION

To cite this article:

Alekseev VV. Flupirtin (katadolon): a nonstandard action on pain transmission. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(4):101‑104. (In Russ.)

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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Keywords:

pathophysiology of pain
chronic pain
muscle spasm
flupirtin

Authors:

Alekseev V.V.

Kafedra voenno-morskoĭ i gospital'noĭ khirurgii Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

List of references:

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  2. Gribova N.P. Primenenie preparata katadolon v lechenii bolevykh sindromov pri radikulomieloishemii. Bol' 2003; 1.
  3. Kamchatnov P.R., Asanov A.Yu. Sovremennye vozmozhnosti farmakoterapii bolevykh sindromov. Bol' 2005; 3: 54-58.
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  12. Block F., Pergande G., Schwarz M. Flupirtine reduced funcional deficits and neuronal damage after global ischaemia in rats. Brain Res 1997; 754: 279-284.
  13. Dickenson A.H. Pharmacology of pain transmission and control.. Pain 1996 - an updated review. Ed. J.N. Campbell 1996; IASP Press: 113-121
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  15. Friedel N.A., Fitton A. Flupirtine. A review of its farmacological properties and therapeutic efficacy in pain states. Dmgs 1993; 45: 548-569.
  16. Komuber J. et al. Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels. J Neural Transm 1999; 106: 857-867.
  17. Muller W.E.G. et.al. Protection offlupirtine on p-amyloid-induced apoptisis in neuronal cells in vitro. J Neurochem 1997; 68: 2371-2377.
  18. Mueller-Schwefe G. Flupirtine in Acute and Chronic Pain Associated with Muscle Tenseness. Results of a Postmarketing Surveillance Study. Fortschr Med 2003; 121: 3-10.
  19. Osbome N.N et al. Protection of rabbit retina from ischemic injury by flupirtine. Invest Ophtalm 1996; 37: 274-280.
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  27. Willis W.D. Signal transduction mechanisms. Pain 1996 - an updated review. Ed J N Campbell 1996; IASP Press 527-531.
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