The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Sivertseva S.A.

Tiumenskiĭ oblastnoĭ tsentr rasseiannogo skleroza

Association analysis between candidate genes for multiple sclerosis and brain MRI parameters

Authors:

Boĭko A.N., Sivertseva S.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1): 84‑88

Read: 3028 times

Download PDF (RU)
Contact the author
Table of contents

ASSOCIATION ANALYSIS BETWEEN CANDIDATE GENES FOR MULTIPLE SCLEROSIS AND BRAIN MRI PARAMETERS
ASSOCIATION ANALYSIS BETWEEN CANDIDATE GENES FOR MULTIPLE SCLEROSIS AND BRAIN MRI PARAMETERS

To cite this article:

Boĭko AN, Sivertseva SA. Association analysis between candidate genes for multiple sclerosis and brain MRI parameters. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1):84‑88. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Pelvic recu­rrences of ovarian cancer: sono­graphic visualization and magnetic reso­nance imaging. P.A. Herzen Journal of Onco­logy. 2024;(5):31-39
Diagnostic value of cross-sectional imaging moda­lities in asse­ssment of peri­toneal carcinomatosis. P.A. Herzen Journal of Onco­logy. 2024;(5):82-88
Low-level laser therapy in multiple scle­rosis: justification and opti­mization methods of application. (Literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;(5):45-56
Glial fibrillary acidic protein: is there a rela­tionship with the course of multiple scle­rosis and traumatic brain injury before the onset of multiple scle­rosis?. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):80-84
An indi­vidual approach to the diagnosis and treatment of an acute psychotic condition in a patient with a multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):97-102
Magnetic reso­nance imaging and PET/CT with 11C-methionine for primary central nervous system vasculitis. Burdenko's Journal of Neurosurgery. 2024;(6):71-76
Brain microstructural abno­rmalities asse­ssed by diffusion kurtosis MRI in patients with focal temporal lobe epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):171-177
Surgical treatment of seco­ndary trigeminal neuralgia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):203-209
Quality of life of patients with multiple scle­rosis in the Smolensk region. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):36-40
Hormonal contraception methods and multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(1):24-30
Abstract:

We studied efficacy and tolerability of the combined drug omaron (25 mg of cinnarizine and 400 mg of piracetam in one tablet) in patients with multiple sclerosis. The dosage of the drug was 1 tablet 3 times a day during 12 weeks in 33 patients (mean age 35.3±4.2 years) of the index group. A comparison group consisted of 27 patients matched for demographic and clinical characteristics who did not receive nootropics during the study. None of patients included in the study received disease modifying drugs. The significant (p<0.05) decrease in the severity of chronic fatigue syndrome (by 28.6% compared to baseline), improvement (p<0.05) of cognitive functions (increase of MMSE scores by 9.4%) were found in the index group compared to the comparison one. The statistically significant changes in the severity of disability assessed by EDSS were not observed. Omaron was well-tolerated with no serious adverse-effects.

Keywords:

multiple sclerosis
HLA-DR
MRI
internuclear index

Authors:

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Sivertseva S.A.

Tiumenskiĭ oblastnoĭ tsentr rasseiannogo skleroza

Close metadata

References:

  1. Vein A.M., Kolosova O.A., Yakovlev N.A., Slyusar' T.A. Migren'. M 1995; 180.
  2. Vtoroi kassifikatsionnyi komitet. Mezhdunarodnaya klassifikatsiya golovnoi boli, 2-e izd. Mezhdunarodnoe obshchestvo golovnoi boli 2003.
  3. Kalashnikova L.A., Korotenkova M.V., Konovalov R.N. Ishemicheskie narusheniya mozgovogo krovoobrashcheniya pri spontannoi dissektsii (rassloenii) ekstra- i intrakranial'nykh arterii. Zhurn nevrol i psikhiatr 2007;332-333 (Insul't, spetsvypusk)
  4. Mukhin K.Yu., Petrukhin A.S. Idiopaticheskie formy epilepsii. M 2000;193-201.
  5. Tabeeva G.R. Migren' i insul't. Consilium Medicum 2910;12:2.
  6. Tul Dzh.F., Gusev E.I. Tranzitornye ishemicheskie ataki: patogenez i klinika. V kn.: Sosudistye zabolevaniya golovnogo mozga. Pod red. E.I. Guseva. M 2007;76-77.
  7. Shtok V.N. Golovnaya bol'. M: Meditsina 1987.
  8. Bougousslavsky J., Regli F., Van Melle G. Migrain stroke. Neurology 1988;38;223-227.
  9. Eriksen M.,Thomsen Lyu, Olesen J. Clinical characteristics of 362 patients with familial migraine with aura. Cephalgia 2004;24:564-575.
  10. Eriksen M.K., Thomsen L.L., Olesen J. Migraine with aura and its borderlands. Classificat Diagnos Headache Dis 2004;62-69.
  11. Henrich J.B., Sandercock P.A.G., Warlow C.P. Stroke and Migraine in the Oxfordshire Community Stroke Project. J Neurol 1986;233:257-262.
  12. Kaul S.N., Du Boulay G.H., Kendall B.E. Relationship between visual fields defect and arterial occlusion in the posterior cerebral circulation. J Neurol Neurosurg Psychiat 1974;37:1022.
  13. Kruit M.C., Van Buchem M.A., Hofman P.A. Migraine as a risk factor for subclinical brain lisions. JAMA 2004;291:427-434.
  14. Kurth T., Gaziano J.M., Cook N.R. et al. Migraine and Risk of Cardiovascular Disease in Women. JAMA 2006;296:283-291.
  15. Manzoni G.C., Farina S. et al. Classic migraine. Clinic findings in 164 patients. Eur Neurol 1985;24:163-169.
  16. Manzoni G.C., Farina S., Granella F. et al. Classic and common migraine. Suggestive clinical evidence of two separateentites. Funct Neurol 1986;1:112-122.
  17. Manzoni G.C., Stovner L.J. Epidemiol Headache 2008
  18. Merilangas K.R., Fenton B.T., Cheng S.H. Association between migraine and stroke in a larg-scale epidemiological study of the United State. Arch Neurol 1997; 54; 362-368.
  19. Milhaud D., Bogousslavsky J., Van Melle G., Liot P. Ischemic stroke and active migraine. Neurology 2001; 57: 1805-1811.
  20. Milligan T.A., Bromfield E. A case of «migralepsy». Epilepsia 2005;46:Suppl 10:2-6.
  21. Panayiotopoulos C.P. Elementary visual hallucination, blindness, and headache in idiopatic occipital epilepsy: differentiation from migraine. J Neurol Neurosurg Psychiat 1999;66:536-540.
  22. Panayiotopoulos C.P. Visual phenomena and headache in occipital epilepsy: a rewiew, a systematic study and differentiation from migraine. Epileptic Dis 1999;1:205-216.
  23. Panayiotopoulos C.P. Occipital lobe epilepsies. In: The Epilepsies:seizures, syndromes and management. Ed. C.P. Panayiotopoulos. Oxford: Blandon Medical Publishing 2005;416-429.
  24. Ramadan J., Tiejen G.E., Levine S.R. Scintillating scotoma associated with internal carotid artery dissection. Neurology 1991;41:1084-1087.
  25. Rothrock J., North J., Madden K. Migraine and migrainose stroke: risk factors and prognosis. Neurology 1993;43:2473-2476.
  26. Russell M.B., Olesen J. A nosographic analysis migraine aura in a general population. Brain 1996;119:355-361.
  27. Silserstein S.D., Lipton R.B., Goatsby P.J. Headache in clinical practice. London: Martin Dunitz 2002;211.
  28. Stovner L.J., Hagen K., Jensen R. et al. The globalburden of headache: a documentation of headache prevalence and disability worldwide. Cephalgia 2007;27:193-210.
  29. Swartz R.H., Kern R.Z. Migraine is associated with magnetic resonance imaging white matter abnormalities: a meta-analisis. Arch Neurol 2004;61:13668.
  30. Thomsen L.L., Eriksen M.K., Roemer S.F. et al. A population-based study of familial hemiplegic migraine suggests revised diagnostic criteria. Brain 2002;125:1379-1391.
  31. Thomsen L.L., Ostergaard E., Olesen J. et al. Evidence for a separate type of migraine with aura: sporadic hemiplegic migraine. Neurology 2003;60:595-601.
  32. Torda C., Wolff H.G. Experimental studies on headache: transient thickening of walls of cranial arteries in relation to certain phenomena of migraine headache and action of ergotamine tartrate on thickened walls. Arch Neurol Psychiat 1945;53:329.
  33. Welch K.M.A. Stroke and migraine - the spectrum of cause and effect. Funct Neurol 2003;18:121-126.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.