Outcomes of endovascular thrombectomy for acute stroke in regional vascular centers of a metropolis (St.-Petersburg)

Savello A.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Vozniuk I.A.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Svistov D.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Babichev K.N.

Military medical Academy named after S. M. Kirov, Saint-Petersburg, Russia

Kandyba D.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Shenderov S.V.

City Multi-Field Hospital №26, St.-Petersburg, Russia

Vlasenko S.V.

Georgievsky Medical Academy, Simferopol, Russia, Crimean Federal University Vernadsky, Simferopol, Russia

Shloydo E.A.

Clinical Hospital №2, St. Petersburg, Russia

Kachesov E.U.

City Multi-Field Hospital «Alexandrovskaya Bolnitsa», St.-Petersburg, Russia

Esipovich I.D.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Haritonova T.V.

Dzhanelidze St. Petersburg Research Institute of Emergency Medicine, St. Petersburg, Russia

Outcomes of endovascular thrombectomy for acute stroke in regional vascular centers of a metropolis (St.-Petersburg)

Authors:

Savello A.V., Vozniuk I.A., Svistov D.V., Babichev K.N., Kandyba D.V., Shenderov S.V., Vlasenko S.V., Shloydo E.A., Kachesov E.U., Esipovich I.D., Haritonova T.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(12‑2): 54‑63

DOI: 10.17116/jnevro201811812254

Downloaded: 31

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Savello AV, Vozniuk IA, Svistov DV, et al. . Outcomes of endovascular thrombectomy for acute stroke in regional vascular centers of a metropolis (St.-Petersburg). S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(12‑2):54‑63. (In Russ.)
https://doi.org/10.17116/jnevro201811812254

Close metadata

Recommended articles:

Features of aphasic disorders in patients with acute cerebrovascular disorder in the posterior cerebral artery basin. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):18-22

The relationship between the development of post-stroke cognitive impairment and changes in the coagulation component of hemostasis. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):23-29

The multidirectional effects of thrombin and the possibility of their control in neurology. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):42-48

Comparative characteristics of the efficacy and safety of the original alteplase and its complete biosimilar in the treatment of ischemic stroke in real clinical practice. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):49-54

Efficacy of Mexidol in combination with cerebral revascularization in the treatment of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):67-74

The secretome of mesenchymal stromal cells as a new hope in the treatment of acute brain tissue injuries. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3-2):83-91

Advisability of carotid endarterectomy in asymptomatic patients. Pirogov Russian Journal of Surgery. 2024;(3):45-53

Hemodynamics and reperfusion in acute ischemic stroke: friends or foes?. Russian Journal of Anesthesiology and Reanimatology. 2024;(2):91-96

Analysis of stroke incidence seasonal changes in Bishkek. Russian Journal of Preventive Medicine. 2024;(4):89-96

Methods of cost-effectiveness evaluation of endovascular patent foramen ovale closure for secondary prevention of cryptogenic stroke. Russian Journal of Preventive Medicine. 2024;(6):105-110

Objective. To assess technical results and close functional outcomes of acute ischemic stroke (AIS) in patients treated with endovascular thrombecomy (ET) in regional vascular centers (RVC) of St-Petersburg. Material and methods. Retrospective analysis of 183 patients with AIS, including 143 patients with AIS due to a large intracranial vessel occlusion in anterior (AC) and 25 patients in posterior cerebral (PC) circulation, 15 with isolated extracranial carotid occlusion treated in 6 RVC in 2017 was performed. All patients underwent ET. Results and conclusion. Effective reperfusion (mTICI 2b—3) was achieved in 71.5% (71.3% AC, 72% PC). On discharge, 35,7% patients had good (mRs 0—2) functional outcome (37.1% AC, 28% PC). The incidence of symptomatic intracranial hemorrhage (according to ECASS II criteria) was 10.7% (9.1% AC, 20% PC), the mortality was 29.2% (22.4% AC, 68% PC).). The results of our study show the possibility of effective and safe application of ET in patients with AIS in the anterior and posterior cerebral circulation in regional vascular centers of St.-Petersburg.

Keywords:

cerebral artery thrombosis

thrombolysis

intravascular thrombectomy

thrombus aspiration

x-ray endovascular diagnosis

ischemic stroke

Authors:

Savello A.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Vozniuk I.A.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Svistov D.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Babichev K.N.

Military medical Academy named after S. M. Kirov, Saint-Petersburg, Russia

Kandyba D.V.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

Shenderov S.V.

City Multi-Field Hospital №26, St.-Petersburg, Russia

Vlasenko S.V.

Georgievsky Medical Academy, Simferopol, Russia, Crimean Federal University Vernadsky, Simferopol, Russia

Shloydo E.A.

Clinical Hospital №2, St. Petersburg, Russia

Kachesov E.U.

City Multi-Field Hospital «Alexandrovskaya Bolnitsa», St.-Petersburg, Russia

Esipovich I.D.

Almazov National Medical Research Centre, St.-Petersburg, Russia

Haritonova T.V.

Dzhanelidze St. Petersburg Research Institute of Emergency Medicine, St. Petersburg, Russia

List of references:

Savello AV, Voznyuk IA, Svistov DV. Vnutrisosudistoye lechenie ishemicheskogo insulta v ostreishem periode (klinicheskie rekomendatsii). SPb.: Assotsiatsiya neirochirurgov Rossii; 2015. (In Russ.)
Hacke W, Kaste M, Fieschi C, von Kummer R, Davalos A, Meier D, Larrue V, Bluhmki E, Davis S, Donnan G, Schneider D, Diez-Tejedor E, Trouillas P. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). second european-australasian acute stroke study investigators. Lancet. 1998;352(9136):1245-1251. https://doi.org/10.1016/s0140-6736(98)08020-9
Toni D, Lorenzano S, Puca E, Prencipe M. The SITS-MOST registry. Neurol Sci. 2006;27(suppl 3):260-262. https://doi.org/10.1007/s10072-006-0632-9
Campbell BC, Mitchell PJ, Kleinig TJ, Dewey HM, Churilov L, Yassi N, Yan B, Dowling RJ, Parsons MW, Oxley TJ, Wu TY, Brooks M, Simpson MA, Miteff F, Levi CR, Krause M, Harrington TJ, Faulder KC, Steinfort BS, Priglinger M, Ang T, Scroop R, Barber PA, McGuinness B, Wijeratne T, Phan TG, Chong W, Chandra RV, Bladin CF, Badve M, Rice H, de Villiers L, Ma H, Desmond PM, Donnan GA, Davis SM; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015;372(11):1009-1018. https://doi.org/10.1056/NEJMoa1414792
Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJ, van Walderveen MA, Staals J, Hofmeijer J, van Oostayen JA, Lycklama à Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de Vries J, de Kort PL, van Rooij WJ, van den Berg JS, van Hasselt BA, Aerden LA, Dallinga RJ, Visser MC, Bot JC, Vroomen PC, Eshghi O, Schreuder TH, Heijboer RJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Marquering HA, Sprengers ME, Jenniskens SF, Beenen LF, van den Berg R, Koudstaal PJ, van Zwam WH, Roos YB, van der Lugt A, van Oostenbrugge RJ, Majoie CB, Dippel DW; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015;372(1):11-20. https://doi.org/10.1056/NEJMoa1411587
Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD. ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015;372(11):1019-1030. https://doi.org/10.1056/NEJMoa1414905
Jovin TG, Chamorro A, Cobo E, de Miquel MA, Molina CA, Rovira A, San Román L, Serena J, Abilleira S, Ribó M, Millán M, Urra X, Cardona P, López-Cancio E, Tomasello A, Castaño C, Blasco J, Aja L, Dorado L, Quesada H, Rubiera M, Hernandez-Pérez M, Goyal M, Demchuk AM, von Kummer R, Gallofré M, Dávalos A; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015;372(24):2296-2306. https://doi.org/10.1056/NEJMoa1503780
Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Singer OC, Jahan R. SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015;372(24):2285-2295. https://doi.org/10.1056/NEJMoa1415061
Cappelen-Smith C, Cordato D, Calic Z, Cheung A, Wenderoth J. Endovascular thrombectomy for acute ischaemic stroke: a real-world experience. Intern Med J. 2016;46(9):1038-1043. https://doi.org/10.1111/imj.13165
Sarzetto F, Gupta S, Alotaibi NM, Howard P, da Costa L, Heyn C, Maralani PJ, Guha D, Swartz RH, Boyle K, Yang VXD. Outcome evaluation of acute ischemic stroke patients treated with endovascular thrombectomy: a single-institution experience in the era of randomized controlled trials. World Neurosurg. 2017;99:593-598. https://doi.org/10.1016/j.wneu.2016.12.054
Wee CK, McAuliffe W, Phatouros CC, Phillips TJ, Blacker D, Singh TP, Baker E, Hankey GJ. Outcomes of endovascular thrombectomy with and without thrombolysis for acute large artery ischaemic stroke at a tertiary stroke centre. Cerebrovasc Dis Extra. 2017;7(2):95-102. https://doi.org/10.1159/000470855
Wiącek M, Kaczorowski R, Homa J, Filip E, Darocha J, Dudek D, Guz W, Bartosik-Psujek H. Single-center experience of stent retriever thrombectomy in acute ischemic stroke. Neurol Neurochir Pol. 2017;51(1):12-18. https://doi.org/10.1016/j.pjnns.2016.09.001
Luo G, Mo D, Tong X, Liebeskind DS, Song L, Ma N, Gao F, Sun X, Zhang X, Wang B, Jia B, Fernandez-Escobar A, Miao Z. Factors associated with 90-day outcomes of patients with acute posterior circulation stroke treated by mechanical thrombectomy. World Neurosurg. 2018;109:318-328. https://doi.org/10.1016/j.wneu.2017.09.171
Gory B, Eldesouky I, Sivan-Hoffmann R, Rabilloud M, Ong E, Riva R, Gherasim DN, Turjman A, Nighoghossian N, Turjman F. Outcomes of stent retriever thrombectomy in basilar artery occlusion: an observational study and systematic review. J Neurol Neurosurg Psychiatry. 2016;87(5):520-525. https://doi.org/10.1136/jnnp-2014-310250

Close metadata