Neurologic disturbances in children with cleft lip and cleft palate

Kovrazhkina E.A.; Starikova N.V.; Nadtochiy A.G.; Gubskiĭ L.V.; Panov V.O.; Volkova K.N.

doi:https://doi.org/10.17116/jnevro20161163276-82

Kovrazhkina E.A.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet;
NII tserebrovaskuliarnoĭ patologii i insul'ta, Moskva

Starikova N.V.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

Nadtochiy A.G.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

Gubskiĭ L.V.

Nauchno-issledovatel'skiĭ institut tserebrovaskuliarnoĭ patologii i insul'ta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Panov V.O.

Russian Medical Academy of Postgraduate Education, Moscow, Russia;
Blochin Russian Oncological Research Center, Moscow, Russia

Volkova K.N.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

Neurologic disturbances in children with cleft lip and cleft palate

Authors:

Kovrazhkina E.A., Starikova N.V., Nadtochiy A.G., Gubskiĭ L.V., Panov V.O., Volkova K.N.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(4‑2): 76‑82

DOI: 10.17116/jnevro20161163276-82

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To cite this article:

Kovrazhkina EA, Starikova NV, Nadtochiy AG, Gubskiĭ LV, Panov VO, Volkova KN. Neurologic disturbances in children with cleft lip and cleft palate. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(4‑2):76‑82. (In Russ.)
https://doi.org/10.17116/jnevro20161163276-82

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))

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Abstract:

Objective. Neurological symptoms of genetic syndromes, including congenital cleft lip and palate (CLP) are well-studied while neurological characteristics of patients with non-syndromal CLP are not described. The authors studied neurological disturbances in CLP. Material and methods. Twenty-one patients with CLP, mean age 12.0±4.7 years (the main group) were compared to healthy people (the control group). Results and conclusion. Elements of bulbar syndrome (atrophy and deviation of the tongue, sagging of the soft palate, specific speech disturbances) and mimic innervation abnormalities (hypomimia or hypermimia, face asymmetry), microfocal neurological symptoms occurred significantly more frequently (p<0.01) in patients of the main group. Bulbar disorders, identified in 100% of the patients, were most characteristic of CLP. The neurological features of patients with CLP demonstrate the involvement of the brain stem, mimic innervation, bulbar cranial nerves and defects of the development of the neural tube.

Keywords:

cleft lip and palate

neurologic disturbances

rehabilitation

magnetic resonance imaging

Authors:

Kovrazhkina E.A.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet;
NII tserebrovaskuliarnoĭ patologii i insul'ta, Moskva

Starikova N.V.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

Nadtochiy A.G.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

Gubskiĭ L.V.

Nauchno-issledovatel'skiĭ institut tserebrovaskuliarnoĭ patologii i insul'ta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Panov V.O.

Russian Medical Academy of Postgraduate Education, Moscow, Russia;
Blochin Russian Oncological Research Center, Moscow, Russia

Volkova K.N.

Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, Russia

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