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Borets O.G.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza (gorodskaia klinicheskaia bol'nitsa #11 Departamenta zdravookhraneniia Moskvy);
kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universtiteta

Davydovskaya M.V.

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

Demina T.L.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Lashch N.Iu.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Khachanova N.V.

Burdenko Neurosurgical Institute, Moscow, Russia

Khasayeva M.V.

Moscow Multiple Sclerosis Center of the City Hospital №24, Moscow;
Pirogov Russian National Research Medical University, Moscow

Shchur S.G.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Experience of using interferon β-1a biosimilans (cinnovex and genfaxon-44) in the Moscow Multiple Sclerosis Center

Authors:

Borets O.G., Davydovskaya M.V., Demina T.L., Lashch N.Iu., Popova N.F., Popova E.V., Khachanova N.V., Khasayeva M.V., Shchur S.G., Boĭko A.N.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(2‑2): 51‑56

DOI: 10.17116/jnevro20151152251-56

Read: 2156 times

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Table of contents

EXPERIENCE OF USING INTERFERON Β-1A BIOSIMILANS (CINNOVEX AND GENFAXON-44) IN THE MOSCOW MULTIPLE SCLEROSIS CENTER
EXPERIENCE OF USING INTERFERON Β-1A BIOSIMILANS (CINNOVEX AND GENFAXON-44) IN THE MOSCOW MULTIPLE SCLEROSIS CENTER

To cite this article:

Borets OG, Davydovskaya MV, Demina TL, et al. . Experience of using interferon β-1a biosimilans (cinnovex and genfaxon-44) in the Moscow Multiple Sclerosis Center. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(2‑2):51‑56. (In Russ.)
https://doi.org/10.17116/jnevro20151152251-56

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Objective. To study the efficacy and tolerability of generics (interferon beta-1a biosimilans) cinnovex for intramascular introduction and genfaxon-44 for subcutaneous injections in multiple sclerosis (MS). Material and methods. One hundred patients were treated with cinnovex and 104 patients were treated with genfaxon-44 during one year. Patient’s status was assessed using clinical approach, psychometric scales and MRI. Results and conclusion. The high percentage of withdrawal of treatment due to the lack of clinical effect and intolerance to the drugs was identified during the treatment. Positive effect with respect to stabilization of MS course was found only in patients who earlier did not receive disease-modifying drugs. Double-blind studies are needed to resolve the question of the adequacy of brand-name drugs and generics.

Keywords:

multiple sclerosis
treatment
DMD
brand-name drugs and generics
interferon beta-1a
cinnovex
genfaxon-44

Authors:

Borets O.G.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza (gorodskaia klinicheskaia bol'nitsa #11 Departamenta zdravookhraneniia Moskvy);
kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universtiteta

Davydovskaya M.V.

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

Demina T.L.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Lashch N.Iu.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Khachanova N.V.

Burdenko Neurosurgical Institute, Moscow, Russia

Khasayeva M.V.

Moscow Multiple Sclerosis Center of the City Hospital №24, Moscow;
Pirogov Russian National Research Medical University, Moscow

Shchur S.G.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

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