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Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Kukel' T.M.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza i kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova;
Okruzhnoe nevrologicheskoe otdelenie GP #180 Severo-Zapadnogo administrativnogo okruga Moskvy

Muravin A.I.

Kafedra akusherstva i ginekologii Pervogo Moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Murashko A.V.

Kafedra akusherstva i ginekologii #1 Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Pregnancy and delivery in women with multiple sclerosis: a retrospective analysis

Authors:

Popova E.V., Kukel' T.M., Muravin A.I., Boĭko A.N., Murashko A.V., Gusev E.I.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(10‑2): 52‑56

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Table of contents

PREGNANCY AND DELIVERY IN WOMEN WITH MULTIPLE SCLEROSIS: A RETROSPECTIVE ANALYSIS
PREGNANCY AND DELIVERY IN WOMEN WITH MULTIPLE SCLEROSIS: A RETROSPECTIVE ANALYSIS

To cite this article:

Popova EV, Kukel' TM, Muravin AI, Boĭko AN, Murashko AV, Gusev EI. Pregnancy and delivery in women with multiple sclerosis: a retrospective analysis. S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(10‑2):52‑56.

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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We have analyzed the course of multiple sclerosis (MS) in 155 pregnant women. In 85.7% cases, pregnancy resulted in delivery and in 14.3% cases - in abortion. Patients presented with relapse very shortly after the abortion and received hormonal treatment. Patients treated with disease-modifying drugs (DMD) did not have relapses during pregnancy compared to those who did not receive DMD before the pregnancy. In the latter group, 33 (40.2%) patients presented with relapses during the I trimester. After the delivery, the relapses were noted in 31 (27.2%) patients during the first year. The maximal number of relapses was recorded to the 3rd month after the delivery (58.1%) with the gradual reduction to the end of the year (6th month - 29% and 12th month - 12.9%). Patients who did not receive DMD had more relapses to the 3rd and 6th months after delivery. In conclusion, the use of DMD before the pregnancy is an important factor for prevention of relapses during pregnancy and after delivery.

Keywords:

multiple sclerosis
pregnancy
delivery
DMD

Authors:

Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Kukel' T.M.

Moskovskiĭ gorodskoĭ tsentr rasseiannogo skleroza i kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova;
Okruzhnoe nevrologicheskoe otdelenie GP #180 Severo-Zapadnogo administrativnogo okruga Moskvy

Muravin A.I.

Kafedra akusherstva i ginekologii Pervogo Moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Murashko A.V.

Kafedra akusherstva i ginekologii #1 Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

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