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Shavlovskaya O.A.

International University of Restorative Medicine», Moscow, Russia

Razumov A.N.

Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

Bokova I.A.

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Shavlovskiy N.I.

Sechenov First Moscow State Medical University (Sechenov University)

Yukhnovskaya Yu.D.

Sechenov First Moscow State Medical University (Sechenov University)

Chondroitin sulfate role in the complex rehabilitation of elderly people with chronic pain syndrome

Authors:

Shavlovskaya O.A., Razumov A.N., Bokova I.A., Shavlovskiy N.I., Yukhnovskaya Yu.D.

More about the authors

Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(1): 71‑78

DOI: 10.17116/kurort20219801171

Views: 2195

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To cite this article:

Shavlovskaya OA, Razumov AN, Bokova IA, Shavlovskiy NI, Yukhnovskaya YuD. Chondroitin sulfate role in the complex rehabilitation of elderly people with chronic pain syndrome. Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(1):71‑78. (In Russ.)
https://doi.org/10.17116/kurort20219801171

Подписка 2025 (Problems of Balneology, Physiotherapy and Exercise Therapy)
 
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The article presents the data of the latest domestic and foreign original studies, the results of a number of meta-analyses, conclusions of randomized clinical trials (RCTs), and other scientific studies that prove the effectiveness and necessity of mandatory inclusion in the treatment of chronic pain syndrome of the stage of non-invasive non-pharmacological therapy. One of the promising areas of pharmacotherapy for degenerative-dystrophic joint lesions is the use of chondroprotectors (CP), in particular chondroitin sulfate (CS). According to new Clinical Recommendations of Ministry Health (MH) of the Russian Federation (RF) «Chronic pain in patients of elderly and senile age» (2020), according to which the purpose of CS is recommended for patients older than 60 years with joint pain and contraindications to non-steroidal anti-inflammatory drugs (NSAIDs) or senile asthenia for the purpose of pain relief and the prevention of exacerbations of pain. A high level of reliability and persuasiveness of the recommendations was noted (1A) of CS use. Most of the CS is available in the form of forms for oral use, the bioavailability of which, according to clinical studies, is 13—38% due to the destruction of the CS molecules in the gastrointestinal tract. Intramuscular (i/m) administration of the drug can increase the bioavailability of CS, which can not only increase the effectiveness of therapy, but also lead to a more rapid development of the symptomatic effect. In Russia available parenteral forms of CS (Chondroguard) pharmaceutical quality, efficacy has been proven in randomized clinical trial (RCT) MH RF. To relieve pain in the joints, it is recommended to use parenteral forms of CS (Chondroguard) at a dose of 100—200 mg per day, every other day, the total duration of the course of treatment is 25—30 injections.

Keywords:

pain
chronic pain syndrome
low back pain
osteoarthritis
rehabilitation
chondroitin sulfate
Chondroguard

Authors:

Shavlovskaya O.A.

International University of Restorative Medicine», Moscow, Russia

Razumov A.N.

Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

Bokova I.A.

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Shavlovskiy N.I.

Sechenov First Moscow State Medical University (Sechenov University)

Yukhnovskaya Yu.D.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

18.01.2020

Accepted:

29.01.2020

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