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Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Yushkina M.A.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

Ogorodnikov D.S.

Kafedra LOR-bolezneĭ Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Immunological disorders in patients with purulent-inflammatory pathology of ENT organs in conditions of comorbidity with diabetes mellitus

Authors:

Krukov A.I., Gurov A.V., Yushkina M.A., Ogorodnikov D.S.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2019;84(6): 22‑27

DOI: 10.17116/otorino20198406122

Read: 1595 times

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Table of contents

IMMUNOLOGICAL DISORDERS IN PATIENTS WITH PURULENT-INFLAMMATORY PATHOLOGY OF ENT ORGANS IN CONDITIONS OF COMORBIDITY WITH DIABETES MELLITUS
IMMUNOLOGICAL DISORDERS IN PATIENTS WITH PURULENT-INFLAMMATORY PATHOLOGY OF ENT ORGANS IN CONDITIONS OF COMORBIDITY WITH DIABETES MELLITUS

To cite this article:

Krukov AI, Gurov AV, Yushkina MA, Ogorodnikov DS. Immunological disorders in patients with purulent-inflammatory pathology of ENT organs in conditions of comorbidity with diabetes mellitus. Russian Bulletin of Otorhinolaryngology. 2019;84(6):22‑27. (In Russ.)
https://doi.org/10.17116/otorino20198406122

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The article discusses the problems of the comorbid course of purulent-inflammatory diseases of the ENT organs and diabetes mellitus. The authors consider the main immunological factors of systemic and tissue immunity, which make it possible to detect immunodeficiency in conditions of purulent inflammation — immunoglobulins A, M, G, phagocytosis parameters, lysozyme, lactoferrin, general bactericidal activity, antibody affinity, determined in blood serum and saliva. In the course of the work, results were obtained that characterize a decrease in the systemic and tissue immune reactivity, which correlate with the degree of compensation of diabetes mellitus, which is a predictor of the occurrence and development of focal suppurative inflammation in the ENT organs. The authors conclude that rational antihyperglycemic therapy is necessary to maintain a satisfactory level of glycemia.

Keywords:

inflammation
ENT organs
immunity
diabetes mellitus
comorbidity

Authors:

Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Yushkina M.A.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

Ogorodnikov D.S.

Kafedra LOR-bolezneĭ Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

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References:

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  7. Gurov AV, Yushkina MA. The peculiar features of the microbial paysage and the problems of antibacterial therapy of the inflammatory ENT diseases in the patients presenting with diabetes mellitus. Vestnik Otorinolaringologii. 2018;83(1):59-61. (In Russ.) https://doi.org/10.17116/otorino201883159-61]
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