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Drozdova E.A.

South-Ural State Medical University

Long-term outcomes of anti-VEGF therapy for macular edema in retinal vein occlusion

Authors:

Drozdova E.A.

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Journal: Russian Annals of Ophthalmology. 2022;138(3): 140‑148

DOI: 10.17116/oftalma2022138031140

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To cite this article:

Drozdova EA. Long-term outcomes of anti-VEGF therapy for macular edema in retinal vein occlusion. Russian Annals of Ophthalmology. 2022;138(3):140‑148. (In Russ.)
https://doi.org/10.17116/oftalma2022138031140

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Antiangiogenic therapy (anti-VEGF) is the standard in the treatment of many retinal vascular diseases, including macular edema associated with retinal vein occlusion (RVO). A large evidentiary basis has been collected, consisting of randomized clinical trials in which anti-VEGF therapy demonstrated a significant advantage over laser photocoagulation and placebo in patients with RVO. However, in everyday clinical practice the results are not always comparable to randomized clinical trials. This review presents an analysis of the current studies based on actual clinical practice. Their results helped identify the main aspects of antiangiogenic therapy that could improve the treatment outcomes for patients with RVO. Additionally, the article discusses the predictive factors for therapy outcomes and the effect of anti-VEGF therapy on the development of neovascular complications in patients with ischemic RVO.

Keywords:

anti-VEGF therapy
macular edema
retinal vein occlusion
real-life practice
aflibercept
ranibizumab

Authors:

Drozdova E.A.

South-Ural State Medical University

Received:

16.03.2022

Accepted:

21.04.2022

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