Lacrimal dysfunction syndrome in patients with COVID-19 as an indicator of the severity of ocular ischemia

Kasymova M.S.

Center for the Development of Professional Qualification of Medical Workers

Iminova M.M.

Republican Clinical Ophthalmological Hospital

Lacrimal dysfunction syndrome in patients with COVID-19 as an indicator of the severity of ocular ischemia

Authors:

Kasymova M.S., Iminova M.M.

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Journal: Russian Annals of Ophthalmology. 2022;138(3): 63‑67

DOI: 10.17116/oftalma202213803163

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To cite this article:

Kasymova MS, Iminova MM. Lacrimal dysfunction syndrome in patients with COVID-19 as an indicator of the severity of ocular ischemia. Russian Annals of Ophthalmology. 2022;138(3):63‑67. (In Russ.)
https://doi.org/10.17116/oftalma202213803163

Подписка 2025 (Russian Annals of Ophthalmology)

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PURPOSE

To assess the state of lacrimal function of the organ of vision in patients suffering from COVID-19 at the time of manifestation of the disease.

MATERIAL AND METHODS

The study included 112 (224 eyes) patients without concurrent ophthalmic pathologies suffering from COVID-19 infection, they were examined at the time of manifestation of the disease. Study patients were divided into two groups depending on the presence or absence of concomitant somatic diseases. In addition to a comprehensive ophthalmological examination, all patients underwent Schirmer’s test (I and II) to measure tear production rate.

RESULTS

Analysis of the results of the study revealed that impaired tear production correlates with insufficient oxygenation of ocular tissues, regardless of patient’s comorbid background. Active oxygen therapy performed in severe cases of the disease further exacerbates the process on the ocular surface.

CONCLUSION

The decrease in tear production observed at the height of the COVID-19 disease in patients with severe and moderately severe course correlates with indicators of blood saturation and index of ischemia, allowing this parameter — the rate of tear production — to be considered as a criterion for the severity of ocular ischemia.

Keywords:

coronavirus

COVID-19

eye

organ of vision

lacrimal dysfunction

Authors:

Kasymova M.S.

Center for the Development of Professional Qualification of Medical Workers

Iminova M.M.

Republican Clinical Ophthalmological Hospital

Received:

10.03.2022

Accepted:

21.04.2022

List of references:

Temporary guidelines. Prevention, diagnosis and treatment of new coronavirus infection (COVID-19) Version 12 (21.09.2021) (Electronic resource). Access date: 21.09.2021 (In Russ.). https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/058/075/original/%D0%92%D0%9C%D0%A0_COVID-19_V12.pdf
Doherty MJ. Ocular manifestations of feline infectious peritonitis. J Am Vet Med Assoc. 1971;159(4):417-424.
Marinho P, Marcos A, Romano A, et al. Retinal findings in patients with COVID-19. Lancet. 2020;395(10237):1610. https://doi.org/10.1016/S0140-6736(20)31014-X
Ryabtseva AA, Grishina EE, Andryukhina OM, Kovrizhkina AA, Andryukhina AS. The eye status in patients after new coronavirus infection. Almanac of Clinical Medicine = Al’manakh klinicheskoy meditsiny. 2020;48(S1):20-26. (In Russ.). https://doi.org/10.18786/2072-0505-2020-48-032
Kurysheva NI. Providing eye care during the COVID-19 pandemic. The Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2021;137(3):106-114. (In Russ.). https://doi.org/10.17116/oftalma2021137031106
Babushkin AE, Saitova GR, Matyukhina EN. Viral conjunctivitis as the first sign of COVID-19 infection (clinical observation). The Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022;138(1):52-56. (In Russ.). https://doi.org/10.17116/oftalma202213801152
Musaev Galbinur PI, Akberova SI, Guseva TS, et al. The effect of actipol on the level of interferon in the lacrimal fluid (clinical and laboratory studies). The Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2001;117(6): 33-35. (In Russ.).
Maychuk DYu, Atlas SN, Loshkareva AO. Ocular manifestations of coronavirus infection COVID-19 (clinical observation). The Russian Annals of Ophthalmology= Vestnik oftal’mologii. 2020;136(4):118-123. (In Russ.). https://doi.org/10.17116/oftalma2020136041118
Yashavantha Rao HC, Jayabaskaran C. The emergence of a novel coronavirus (SARS-CoV-2) disease and their neuroinvasive propensity may affect in COVID-19 patients. J Med Virol. 2020;92(7):786-790. https://doi.org/10.1002/jmv.25918
Casagrande M, Fitzek A, Püschel K, Aleshcheva G, Schultheiss H-P, Berneking L, et al. Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients. Ocul Immunol Inflamm. 2020;28(5):721-725. https://doi.org/10.1080/09273948.2020.1770301
Seah I, Agrawal R. Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals. Ocul Immunol Inflamm. 2020;28(3):391-395. https://doi.org/10.1080/09273948.2020.1738501
Kasimova MS, Makhkamova DK, Hamraeva GH. Peculiarities of the course of ocular ischemic syndrome in chronic cerebrovascular iscemia. Oftal’mologiya. 2013;3(10):63-67. (In Russ.).

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