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Safonova T.N.

Krasnov Research Institute of Eye Diseases

Medvedeva E.S.

Regional Clinical Hospital

Modern possibilities of studying the composition of meibomian glands secretion

Authors:

Safonova T.N., Medvedeva E.S.

More about the authors

Journal: Russian Annals of Ophthalmology. 2022;138(1): 84‑89

DOI: 10.17116/oftalma202213801184

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To cite this article:

Safonova TN, Medvedeva ES. Modern possibilities of studying the composition of meibomian glands secretion. Russian Annals of Ophthalmology. 2022;138(1):84‑89. (In Russ.)
https://doi.org/10.17116/oftalma202213801184

Подписка 2025 (Russian Annals of Ophthalmology)
 
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As the main source of various lipids, the meibomian glands are involved in the formation of lipid layer of the tear film and the maintenance of homeostasis of the ocular surface. This process is directly dependent on the chemical composition and thickness of the lipid layer. In addition to lipid components, the meibum also contains various proteins that affect the properties of the tear film. The introduction of various modifications of mass spectrometry into clinical practice is a new diagnostic approach that allows obtaining information about the composition of meibomian glands secretion and tears.

Keywords:

meibomian gland dysfunction
meibum
lipidome
mass spectrometry
proteomic analysis
dry eye syndrome
tear film

Authors:

Safonova T.N.

Krasnov Research Institute of Eye Diseases

Medvedeva E.S.

Regional Clinical Hospital

Received:

19.04.2021

Accepted:

02.06.2021

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