Influence of cataract phacoemulsification on eye hydrodynamics in patients with prior trabeculectomy

Close metadata

Recommended articles:

First experience of implantation of extended depth of focus intraocular lenses in patients with glaucoma. Russian Annals of Ophthalmology. 2024;(3):70-74

Possibilities of physiotherapy in glaucomatous optic neuropathy after glaucoma surgery. Russian Annals of Ophthalmology. 2024;(3):88-94

Efficacy of drainage implants in combined cataract and glaucoma surgery. Russian Annals of Ophthalmology. 2024;(4):33-39

The role of mitochondrial dysfunction in the stabilization of the glaucomatous process. Russian Annals of Ophthalmology. 2024;(4):49-58

Efficacy and safety of the fixed combination of dorzolamide/timolol (Dorzotimol) in primary open-angle glaucoma. Russian Annals of Ophthalmology. 2024;(5):125-129

Combined approach to cataract surgery in keratoconus. Russian Annals of Ophthalmology. 2024;(6):107-111

The results of fistulizing glaucoma surgeries in pseudophackic patients. Russian Annals of Ophthalmology. 2025;(1):45-52

The role of the structure of the lamina cribrosa in the diagnosis and treatment of glaucoma. Structural and circulatory changes in the lamina cribrosa with aging and elevated intraocular pressure. Russian Annals of Ophthalmology. 2025;(1):76-82

Neuroprotective therapy of glaucoma. Russian Annals of Ophthalmology. 2025;(1):83-90

The relationship between neuropsychological indicators and neuroimaging changes according to MRI morphometry in patients with Alzheimer’s disease and glaucoma. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):142-152

At present, phacoemulsification and trabeculectomy are the most widespread surgery methods in cataract and glaucoma treatment, generally recognized as the gold standard. Among elderly patients, comorbid glaucoma and cataract are extremely prevalent, so the order of the two surgeries and the time interval between them are pivotal choices when planning treatment strategy. The reason for it is that almost any eye surgery is considered a risk factor for long-term trabeculectomy effectiveness. In attempts to solve this problem, numerous studies have been conducted on the impact of cataract surgery on filtration bleb scarring. The problem of determining the time interval between surgeries, as well as other treatment nuances, remains relevant despite the long history of research and publications. Some results are cited as general recommendations on treatment tactics (increasing the time interval between operations, using antimetabolite and anti-inflammatory therapy, minimizing intraoperative traumatism). However, currently there are no specific recommendations for one of the most important factors — the time interval between cataract extraction and trabeculectomy.

Keywords:

primary open-angle glaucoma

cataract

phacoemulsification

trabeculectomy

bleb scarring

Authors:

Avetisov S.É.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Erichev V.P.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Petrov S.Iu.

FGBU "NII glaznykh bolezneĭ" RAMN

Volzhanin A.V.

Research Institute of Eye Diseases, 11, A, B, Rossolimo St., Moscow, Russian Federation, 119021

List of references:

Fontana H, Nouri-Mahdavi K, Caprioli J. Trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma: outcomes and risk factors for failure. American Journal of Ophthalmology. 2006;141(4):652-659. https://doi.org/10.1016/j.ajo.2005.11.039
Fontana H, Nouri-Mahdavi K, Lumba J, Ralli M, Caprioli J. Trabeculectomy with mitomycin C: outcomes and risk factors for failure in phakic open-angle glaucoma. Ophthalmology. 2006;113(6):930-936. https://doi.org/10.1016/j.ophtha.2006.01.062
Bessmertniy AM. To the question on the differentiated surgical treatment of basic forms refractory glaucoma. RMZH Klinicheskaya oftal’mologiya. 2005;2:80-82 (In Russ.)
Dickens MA, Cashwell LF. Long-term effect of cataract extraction on the function of an established filtering bleb. Ophthalmic Surgery and Lasers. 1996;27(1):9-14.
Investigators A. The Advanced Glaucoma Intervention Study: 8. Risk of cataract formation after trabeculectomy. Archives of Ophthalmology. 2001;119(12):1771-1779.
Jampel HD, Solus JF, Tracey PA, Gilbert DL, et al. Outcomes and bleb-related complications of trabeculectomy. Ophthalmology. 2012;119(4):712-722. https://doi.org/10.1016/j.ophtha.2011.09.049
Musch DC, Gillespie BW, Niziol LM, Janz NK, et al. Cataract extraction in the collaborative initial glaucoma treatment study: incidence, risk factors, and the effect of cataract progression and extraction on clinical and quality-of-life outcomes. Archives of ophthalmology. 2006;124(12):1694-1700. https://doi.org/10.1001/archopht.124.12.1694
Robin AL, Ramakrishnan R, Krishnadas R, Smith SD, et al. A long-term dose-response study of mitomycin in glaucoma filtration surgery. Archives of Ophthalmology. 1997;115(8):969-974.
Wilkins M, Indar A, Wormald R. Intra-operative mitomycin C for glaucoma surgery. The Cochrane database of systematic reviews. 2001;(1):CD002897. https://doi.org/10.1002/14651858.CD002897
Manoj B, Chako D, Khan MY. Effect of extracapsular cataract extraction and phacoemulsification performed after trabeculectomy on intraocular pressure. Journal of Cataract and Refractive Surgery. 2000;26(1):75-78.
Chiselita D, Antohi I, Medvichi R, Danielescu C, et al. The influence of cataract surgery on the efficacy of trabeculectomy in patients with open-angle glaucoma. Oftalmologia. 2004;48(2):71-80.
Chee SP, Ti SE, Sivakumar M, Tan DT. Postoperative inflammation: extracapsular cataract extraction versus phacoemulsification. Journal of Cataract and Refractive Surgery. 1999;25(9):1280-1285.
Crichton AC, Kirker AW. Intraocular pressure and medication control after clear corneal phacoemulsification and AcrySof posterior chamber intraocular lens implantation in patients with filtering blebs. Journal of Glaucoma. 2001;10(1):38-46.
Rebolleda G, Munoz-Negrete FJ. Phacoemulsification in eyes with functioning filtering blebs: a prospective study. Ophthalmology. 2002;109(12):2248-2255.
Chen PP, Weaver YK, Budenz D., Feuer WJ, Parrish RK, 2nd. Trabeculectomy function after cataract extraction. Ophthalmology. 1998;105(10):1928-1935. https://doi.org/10.1016/S0161-6420(98)91044-2
Mietz H, Andresen A, Welsandt G, Krieglstein GK. Effect of cataract surgery on intraocular pressure in eyes with previous trabeculectomy. Graefe’s archive for clinical and experimental ophthalmology. 2001;239(10):763-769.
Wang X, Zhang H, Li S, Wang N. The effects of phacoemulsification on intraocular pressure and ultrasound biomicroscopic image of filtering bleb in eyes with cataract and functioning filtering blebs. Eye. 2009;23(1):112-116. https://doi.org/10.1038/sj.eye.6702981
Inal A, Bayraktar S, Inal B, Bayraktar Z, Yilmaz OF. Intraocular pressure control after clear corneal phacoemulsification in eyes with previous trabeculectomy: a controlled study. Acta ophthalmologica Scandinavica. 2005;83(5):554-560. https://doi.org/10.1111/j.1600-0420.2005.00497.x
Park HJ, Kwon YH, Weitzman M, Caprioli J. Temporal corneal phacoemulsification in patients with filtered glaucoma. Archives of Ophthalmology. 1997;115(11):1375-1380.
Shrivastava A, Singh K. The effect of cataract extraction on intraocular pressure. Current Opinion in Ophthalmology. 2010;21(2):118-122. https://doi.org/10.1097/ICU.0b013e3283360ac3
Mantseva YaYu, Astakhov SYu, Ananyevskaya PV, Titarenko AI. The influence of phacoemulsification on the intraocular pressure level in patients with co-existing cataract and open-angle glaucoma. Oftal’mologicheskie Vedomosti. 2013;6(1):29-34 (In Russ.)
Mansberger SL, Gordon MO, Jampel H, Bhorade A, et al. Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study. Ophthalmology. 2012;119(9):1826-1831. https://doi.org/10.1016/j.ophtha.2012.02.050
Chen PP, Lin SC, Junk AK, Radhakrishnan S, Singh K, Chen TC. The Effect of Phacoemulsification on Intraocular Pressure in Glaucoma Patients: A Report by the American Academy of Ophthalmology. Ophthalmology. 2015;122(7):1294-1307. https://doi.org/10.1016/j.ophtha.2015.03.021
Mathalone N, Hyams M, Neiman S, Buckman G, Hod Y, Geyer O. Long-term intraocular pressure control after clear corneal phacoemulsification in glaucoma patients. Journal of cataract and refractive surgery. 2005;31(3):479-483. https://doi.org/10.1016/j.jcrs.2004.06.046
Shingleton BJ, Gamell LS, O’Donoghue MW, Baylus SL, King R. Long-term changes in intraocular pressure after clear corneal phacoemulsification: normal patients versus glaucoma suspect and glaucoma patients. Journal of Cataract and Refractive Surgery. 1999;25(7):885-890.
Casson R, Rahman R, Salmon JF. Phacoemulsification with intraocular lens implantation after trabeculectomy. Journal of Glaucoma. 2002;11(5):429-433.
Swamynathan K, Capistrano AP, Cantor LB, WuDunn D. Effect of temporal corneal phacoemulsification on intraocular pressure in eyes with prior trabeculectomy with an antimetabolite. Ophthalmology. 2004;111(4):674-678. https://doi.org/10.1016/j.ophtha.2003.08.025
Klink J, Schmitz B, Lieb WE, Klink T, et al. Filtering bleb function after clear cornea phacoemulsification: a prospective study. The British Journal of Ophthalmology. 2005;89(5):597-601. https://doi.org/10.1136/bjo.2004.041988
Derbolav A, Vass C, Menapace R, Schmetterer K, Wedrich A. Long-term effect of phacoemulsification on intraocular pressure after trabeculectomy. Journal of Cataract and Refractive Surgery. 2002;28(3):425-430.
Husain R, Liang S, Foster PJ, Gazzard G, et al. Cataract surgery after trabeculectomy: the effect on trabeculectomy function. Archives of Ophthalmology. 2012;130(2):165-170. https://doi.org/10.1001/archophthalmol.2011.329
Awai-Kasaoka N, Inoue T, Takihara Y, Kawaguchi A, et al. Impact of phacoemulsification on failure of trabeculectomy with mitomycin-C. Journal of Cataract and Refractive Surgery. 2012;38(3):419-424. https://doi.org/10.1016/j.jcrs.2011.09.035
Ehrnrooth P, Lehto I, Puska P, Laatikainen L. Phacoemulsification in trabeculectomized eyes. Acta Ophthalmologica Scandinavica. 2005;83(5):561-566. https://doi.org/10.1111/j.1600-0420.2005.00499.x
Sharma TK, Arora S, Corridan PG. Phacoemulsification in patients with previous trabeculectomy: role of 5-fluorouracil. Eye. 2007;21(6):780-783. https://doi.org/10.1038/sj.eye.6702327
Wong TT, Khaw PT, Aung T, Foster PJ, et al. The singapore 5-Fluorouracil trabeculectomy study: effects on intraocular pressure control and disease progression at 3 years. Ophthalmology. 2009;116(2):175-184. https://doi.org/10.1016/j.ophtha.2008.09.049
Shahid H, Salmon JF. Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery. Journal of Ocular Pharmacology and Therapeutics: the Official Journal of the Association for Ocular Pharmacology and Therapeutics. 2010;26(1):119-123. https://doi.org/10.1089/jop.2009.0067
Nguyen DQ, Niyadurupola N, Tapp RJ, O’Connell RA, Coote MA, Crowston JG. Effect of phacoemulsification on trabeculectomy function. Clinical & Experimental Ophthalmology. 2014;42(5):433-439. https://doi.org/10.1111/ceo.12254
Longo A, Uva MG, Reibaldi A, Avitabile T, Reibaldi M. Long-term effect of phacoemulsification on trabeculectomy function. Eye. 2015;29(10):1347-1352. https://doi.org/10.1038/eye.2015.108
Patel HY, Danesh-Meyer HV. Incidence and management of cataract after glaucoma surgery. Current Opinion in Ophthalmology. 2013;24(1):15-20. https://doi.org/10.1097/ICU.0b013e32835ab55f
Vass C, Menapace R. Surgical strategies in patients with combined cataract and glaucoma. Current Opinion in Ophthalmology. 2004;15(1):61-66.
Mathew RG, Murdoch IE. The silent enemy: a review of cataract in relation to glaucoma and trabeculectomy surgery. The British Journal of Ophthalmology. 2011;95(10):1350-1354. https://doi.org/10.1136/bjo.2010.194811

Close metadata