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Trubnikova O.A.

FGBU "NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ" SO RAMN, Kemerovo

Tarasova I.V.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia

Maleva O.V.

FGBU "NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ" SO RAMN, Kemerovo

Kagan E.S.

Kemerovo State University, Kemerovo, Russia

Barbarash O.L.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Barbarash L.S.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

Factors for the development of persistent postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery under extracorporeal circulation

Authors:

Trubnikova O.A., Tarasova I.V., Maleva O.V., Kagan E.S., Barbarash O.L., Barbarash L.S.

More about the authors

Journal: Therapeutic Archive. 2017;89(9): 41‑47

DOI: 10.17116/terarkh201789941-47

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Table of contents

FACTORS FOR THE DEVELOPMENT OF PERSISTENT POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS SURGERY UNDER EXTRACORPOREAL CIRCULATION
FACTORS FOR THE DEVELOPMENT OF PERSISTENT POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS SURGERY UNDER EXTRACORPOREAL CIRCULATION

To cite this article:

Trubnikova OA, Tarasova IV, Maleva OV, Kagan ES, Barbarash OL, Barbarash LS. Factors for the development of persistent postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery under extracorporeal circulation. Therapeutic Archive. 2017;89(9):41‑47. (In Russ.)
https://doi.org/10.17116/terarkh201789941-47

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Abstract:

Aim. To analyze the factors contributing to the increased risk of persistent postoperative cognitive dysfunction (POCD) in patients undergoing coronary artery bypass surgery (CABS) under extracorporeal circulation (EC). Subjects and methods. 257 male patients aged 45 to 69 years with coronary heart disease (CHD) undergoing elective CABS under EC were examined. In addition to conventional clinical examination, all the patients underwent neuropsychological testing 3—5 days before, 7—14 days and 1 year after CABS. Persistent POCD was diagnosed if there was a 20% decline in cognitive domains at 1-year postoperatively versus preoperatively in 20% of the tests of an entire neuropsychological battery. Binary logistic regression analysis was applied to identify the factors supposedly increasing the risk of persistent POCD. Results. It was found that high baseline cognitive status, early POCD after CABG under EC, low adherence to the prescribed treatment regimen, as well as progressive carotid artery (CA) stenosis could predict with a high (85%) probability that persistent POCD might develop at 1 year after surgery. Conclusion. The findings are suggestive of the multifactorial origin of persistent POCD, a significant role in the development of which is played by not only the preoperative cognitive status, but also by postoperative factors, such as the degree of adherence to the prescribed treatment regimen, early POCD, and progressive CA stenosis.

Keywords:

coronary artery bypass surgery
extracorporeal circulation
postoperative cognitive dysfunction
carotid artery stenosis
degree of adherence to the prescribed treatment regimen

Authors:

Trubnikova O.A.

FGBU "NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ" SO RAMN, Kemerovo

Tarasova I.V.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia

Maleva O.V.

FGBU "NII kompleksnykh problem serdechno-sosudistykh zabolevaniĭ" SO RAMN, Kemerovo

Kagan E.S.

Kemerovo State University, Kemerovo, Russia

Barbarash O.L.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Barbarash L.S.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

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References:

  1. Tsai TL, Sands LP, Leung JM. An update on postoperative cognitive dysfunction. Adv Anesth. 2010;28(1):269-284. https://doi.org/10.1016/j.aan.2010.09.003
  2. Steinmetz J, Christensen KB, Lund T, Lohse N, Rasmussen LS, ISPOCD Group. Long-term consequences of postoperative cognitive dysfunction. Anesthesiology. 2009;110(3):548-555. https://doi.org/10.1097/ALN.0b013e318195b569
  3. Deiner S, Silverstein JH. Postoperative delirium and cognitive dysfunction. Br J Anaesth. 2009;1:41-46. https://doi.org/10.1093/bja/aep291
  4. Bokeriya LA, Golukhova EZ, Polunina AG, Lefterova NP, Begachev AV. Kognitivnye funktsii posle operatsii s iskusstvennym krovoobrashcheniem v rannem i otdalennom posleoperatsionnom periode. Kreativnaya kardiologiya. 2011;2:71-88. (In Russ.).
  5. Krenk L, Rasmussen LS. Postoperative delirium and postoperative cognitive dysfunction in the elderly — what are the differences? Minerva Anestesiol. 2011;77(7):742-749. http://www.minervamedica.it/foto_riviste/02.jpg
  6. Patron E, Messerotti Benvenuti S, Zanatta P, Polesel E, Palomba D. Preexisting depressive symptoms are associated with long-term cognitive decline in patients after cardiac surgery. Gen Hosp Psychiatry. 2013;35(5):472-479. https://doi.org/10.1016/j.genhosppsych.2013.05.004
  7. Ille R, Lahousen T, Schweiger S, Hofmann P, Kapfhammer HP. Influence of patient-related and surgery-related risk factors on cognitive performance, emotional state, and convalescence after cardiac surgery. Cardiovasc Revasc Med. 2007;8(3):166-169. https://doi.org/10.1016/j.carrev.2006.12.001
  8. Kadoi Y, Goto F. Sevoflurane anesthesia did not affect postoperative cognitive dysfunction in patients undergoing coronary artery bypass graft surgery. J Anesth. 2007;21(3):330-335. https://doi.org/10.1007/s00540-007-/0537
  9. Rukovodstvo po kardioanesteziologii. Pod red. Bunatyana AA, Trekovoi NA. M.: Izdatel’stvo MIA; 2005. (In Russ.).
  10. Artero S, Petersen R, Touchon J, Ritchie K. Revised criteria for mild cognitive impairment: validation within a longitudinal population study. Dement Geriatr Cogn Disord. 2006;22:465-470. https://doi.org/10.1159/000096287
  11. Trubnikova OA, Tarasova IV, Mamontova AS, Syrova ID, Maleva OV, Barbarash OL. Ctruktura kognitivnykh narushenii i dinamika bioelektricheskoi aktivnosti mozga u patsientov posle pryamoi revaskulyarizatsii miokarda. Rossiiskii kardiologicheskii zhurnal. 2014;8(112):57-62. (In Russ.).
  12. Selnes OA, Gottesman RF, Grega MA, Baumgartner WA, Zeger SL, McKhann GM. Cognitive and neurologic outcomes after coronaryartery bypass surgery. N Engl J Med. 2012;366(3):250-257. https://doi.org/10.1056/NEJMra1100109
  13. Mathew A, Eliasziw M, Devereaux PJ, Merino JG, Barnett HJ, Garg AX. Carotid endarterectomy benefits patients with CKD and symptomatic high-grade stenosis.; North American Symptomatic Carotid Endarterectomy Trial (NASCET) Collaborators. J Am Soc Nephrol. 2010;21(1):145-152. https://doi.org/10.1681/ASN.2009030287
  14. Kolesnikov AO. Kompleksnaya otsenka pamyati i vnimaniya u lits yunosheskogo vozrasta. Elektronnyi nauchnyi zhurnal Sovremennye problemy nauki i obrazovaniya. 2013;3:99. Ssylka aktivna na 29.06.2017. (In Russ.). https://www.science-education.ru/images/gerb-100.png
  15. Chernov VI, Efimova NY, Efimova IY, Akhmedov SD, Lishmanov YB. Short-term and long-term cognitive function and cerebral perfusion in off-pump and on-pump coronary artery bypass patients. Eur J Cardiothorac Surg. 2006;29(1):74-81. https://doi.org/10.1016/j.ejcts.2005.10.001
  16. Tan AMY, Amoako D. Postoperative cognitive dysfunction after cardiac surgery. Contin Educ Anaesth Crit Care. 2013;13(6):218-223. https://doi.org/10.1093/bjaceaccp/mkt022
  17. Pogosova, GV Belova YuS, Roslavtseva AN. Priverzhennost’ k lecheniyu arterial’noi gipertonii i ishemicheskoi bolezni serdtsa — klyuchevoi element snizheniya serdechno-sosudistoi smertnosti. Kardiovaskulyarnaya terapiya i profilaktika. 2007;1:99-104. (In Russ.).
  18. Pomeshkina SA, Borovik IV, Krupyanko EV. i dr. Priverzhennost’ k medikamentoznoi terapii bol’nykh ishemicheskoi bolezn’yu serdtsa, podvergshikhsya koronarnomu shuntirovaniyu. Sibirskii meditsinskii zhurnal. 2013;28(4):71-76. (In Russ.).
  19. Choudhry NK, Glynn RJ, Avorn J, Lee JL, Brennan TA, Reisman L, Toscano M, Levin R, Matlin OS, Antman EM, Shrank WH. Untangling the relationship between medication adherence and post-myocardial infarction outcomes: medication adherence and clinical outcomes. Am Heart J. 2014;167(1):51-58.e5. https://doi.org/10.1016/j.ahj.2013.09.014
  20. Bokeriya LA, Kamchatnov PR, Klyuchnikov IV, Alaverdyan AG, Gusev EI. Tserebrovaskulyarnye rasstroistva u bol’nykh s koronarnym shuntirovaniem. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2008;3:90-94. (In Russ.).
  21. Mehta RH, Bhatt DL, Steg PG, Goto S, Hirsch AT, Liau CS, Röther J, Wilson PW, Richard AJ, Eagle KA, Ohman EM. Modifiable risk factors control and its relationship with 1 year outcomes after coronary artery bypass surgery: insights from the REACH registry. Eur Heart J. 2008;29(24):3052-3060. https://doi.org/10.1093/eurheartj/ehn478
  22. Biryukova LA. Priverzhennost’ k lecheniyu bol’nykh ishemicheskoi bolezn’yu serdtsa s bolevoi i bezbolevoi formoi. Sibirskii meditsinskii zhurnal. (Irkutsk). 2008;79(4):75-77. (In Russ.).
  23. Lam LC, Chan WC, Leung T, Fung AW, Leung EM. Would older adults with mild cognitive impairment adhere to and benefit from a structured lifestyle activity intervention to enhance cognition?: a cluster randomized controlled trial. PLoS One. 2015;10(3):e0118173. https://doi.org/10.1371/journal.pone.0118173
  24. Maekawa K, Goto T, Baba T, Yoshitake A, Katahira K, Yamamoto T. Impaired cognition preceding cardiac surgery is related to cerebral ischemic lesions. J Anesth. 2011;25(3):330-336. https://doi.org/10.1007/s00540-011-1108-5
  25. Boodhwani M, Rubens FD, Wozny D, Rodriguez R, Alsefaou A, Hendry PJ, Nathan HJ. Predictors of early neurocognitive deficits in low-risk patients undergoing on-pump coronary artery bypass surgery. Circulation. 2006;114(1,Suppl.):I461-466. https://doi.org/10.1161/CIRCULATIONAHA.105.001354
  26. Barbarash LS, Plotnikov GP, Shukevich DL, Grigor’ev EV, Shukevich LE. Gemodinamika i gidrodinamicheskii status pri sistemnom vospalitel’nom otvete infektsionnoi i neinfektsionnoi etiologii na fone prodolzhitel’noi zamestitel’noi pochechnoi terapii. Patologiya krovoobrashcheniya i kardiokhirurgiya. 2010;4:42-45. (In Russ.).
  27. Bokeriya LA, Bukharin VA, Rabotnikov VS, Alshibaya MD. Khirurgicheskoe lechenie bol’nykh ishemicheskoi bolezn’yu serdtsa s porazheniem brakhiotsefal’nykh arterii. Izd. 2-e, ispr. i dopoln. M.: NTsSSKh im. A.N. Bakuleva RAMN. 2006. (In Russ.).
  28. Balestrini S, Perozzi C, Altamura C, Vernieri F, Luzzi S, Bartolini M, Provinciali L., Silvestrini M. Severe carotid stenosis and impaired cerebral hemodynamics can influence cognitive deterioration. Neurology. 2013;80(23):2145-2150. https://doi.org/10.1212/WNL.0b013e318295d71a.
  29. Mathiesen EB, Waterloo K, Joakimsen O, Bakke SJ, Jacobsen EA, Bønaa KH. Reduced neuropsychological test performance in asymptomatic carotid stenosis: The Tromso Study. Neurology. 2004;62(5):695-701. https://doi.org/10.1212/01.WNL.0000113759.80877.1F
  30. Bairakova YuV, Bazdyrev ED, Kazachek YaV, Kalichenko NA, Bezdenezhnykh NA, Gruzdeva OV, Ivanov SV, Barbarash OL. Prognosticheskaya rol’ S-reaktivnogo belka v progressirovanii ateroskleroza cherez god posle koronarnogo shuntirovaniya. Kardiologiya. 2013;53(6):40-45. (In Russ.).
  31. Newman, M. Open heart surgery and cognitive decline. Cleve Clin J Med. 2007;74(Suppl.1):S52-55.
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