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Shcherbak A.V.

Otdel nefrologii NII uronefrologii i reproduktivnogo zdorov'ia cheloveka

Kozlovskaia L.V.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

Bobkova I.N.

Otdel nefrologii NII uronefrologii i reproduktivnogo zdorov'ia cheloveka Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

Balkarov I.M.

Kafedra terapii i professional'nykh bolezneĭ mediko-profilakticheskogo fakul'teta Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

Lebedeva M.V.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Stakhova T.Iu.

Kafedra terapii i professional'nykh bolezneĭ mediko-profilakticheskogo fakul'teta Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

Hyperuricemia and the problem of chronic kidney disease

Authors:

Shcherbak A.V., Kozlovskaia L.V., Bobkova I.N., Balkarov I.M., Lebedeva M.V., Stakhova T.Iu.

More about the authors

Journal: Therapeutic Archive. 2013;85(6): 100‑104

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Table of contents

HYPERURICEMIA AND THE PROBLEM OF CHRONIC KIDNEY DISEASE
HYPERURICEMIA AND THE PROBLEM OF CHRONIC KIDNEY DISEASE

To cite this article:

Shcherbak AV, Kozlovskaia LV, Bobkova IN, Balkarov IM, Lebedeva MV, Stakhova TIu. Hyperuricemia and the problem of chronic kidney disease. Therapeutic Archive. 2013;85(6):100‑104. (In Russ.)

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Abstract:

The paper reviews the literature on the role of hyperuricemia as a risk factor for chronic kidney disease and as one of the factors for the progression of existing kidney disease. It gives epidemiological information on a relationship between hyperuricemia and kidney lesion. The mechanisms for the damaging action of uric acid on kidney tissue, which have experimentally and clinically observed, are considered. The main areas of hyperuricemia correction and its place in the total nephroprotection strategy are defined.

Keywords:

hyperuricemia
gout
chronic kidney disease
tubulointerstitial fibrosis
epithelial-mesenchymal transdifferentiation

Authors:

Shcherbak A.V.

Otdel nefrologii NII uronefrologii i reproduktivnogo zdorov'ia cheloveka

Kozlovskaia L.V.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

Bobkova I.N.

Otdel nefrologii NII uronefrologii i reproduktivnogo zdorov'ia cheloveka Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

Balkarov I.M.

Kafedra terapii i professional'nykh bolezneĭ mediko-profilakticheskogo fakul'teta Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

Lebedeva M.V.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Stakhova T.Iu.

Kafedra terapii i professional'nykh bolezneĭ mediko-profilakticheskogo fakul'teta Pervogo MGMU im. I.M. Sechenova Minzdrava Rossii

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