Introduction. The global objectives of WHO in the field of oral health by 2020 include the average intensity of caries among 12-year-old children no more than 1.5 by the DMFT index. In Samara the value of the DMFT among the adolescents at age 12 is 3.5. Objective. Is to identify the appropriate timing for a launching of community-based schemes of dental caries prevention of permanent teeth for children of Samara. Materials and methods. In a cross-sectoral multisample research from March to May 2017, the time of eruption and intensity of caries of the first permanent molars among children in Samara were studied. A total of 405 children aged 5 to 8, attending preschool and school educational institutions were examined. The quantity and the stage of eruption of the first permanent molars were assessed; the initial and manifest forms of caries were considered during the calculation of indexes of caries intensity of teeth and surfaces. Results. One to four first permanent molars were erupted among 26.3% of children aged 5, at an average 0.6±0.14 per one surveyed, the prevalence of caries of the first permanent molars was equal to 1.3%, including 1.3% of the initial carious defeats. In 6-year-old children — 65% had the first permanent molars, at an average of 2.38±0.199, and the prevalence of caries in these teeth was 29.63%, including initial forms of caries 27.16%. The results among 7-year-old children — 87.18% and 3.12±0.156, 60.3% and 51.28%, respectively. In 8-year-old children these figures were equal: 97.26%, 3.79±0.091, 68.49% and 60.27%, respectively. The rate of eruption of the first permanent molars and the prevalence of their carious lesions among girls was significantly higher than among boys. Conclusion. The optimal age of children of Samara for inclusion in the regional programs of dental caries prevention is the age of 4 years — the age of the beginning of the first permanent molar eruption.