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Semkin V.A.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Rabinovich O.F.

Otdelenie patologii slizistoĭ obolochki rta FGBU TsNIIS i ChLKh Minzdrava Rossii, Moskva

Agapitova L.P.

Central Research Institute of Stomatology and Maxillofacial Surgery Health Ministry, Moscow, Russia

Bezrukov A.A.

Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia

Babichenko I.I.

Russian University of People’s Friendship, Moscow, Russia, 117198

Diagnostic value of optical coherence tomography for oral leukoplakia assessment

Authors:

Semkin V.A., Rabinovich O.F., Agapitova L.P., Bezrukov A.A., Babichenko I.I.

More about the authors

Journal: Stomatology. 2018;97(1): 37‑39

DOI: 10.17116/stomat201897137-39

Views: 1491

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Table of contents

DIAGNOSTIC VALUE OF OPTICAL COHERENCE TOMOGRAPHY FOR ORAL LEUKOPLAKIA ASSESSMENT
DIAGNOSTIC VALUE OF OPTICAL COHERENCE TOMOGRAPHY FOR ORAL LEUKOPLAKIA ASSESSMENT

To cite this article:

Semkin VA, Rabinovich OF, Agapitova LP, Bezrukov AA, Babichenko II. Diagnostic value of optical coherence tomography for oral leukoplakia assessment. Stomatology. 2018;97(1):37‑39. (In Russ.)
https://doi.org/10.17116/stomat201897137-39

Подписка 2025-2 (Stomatology)
 
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The article presents a comparative analysis of the results of in vivo scanning of oral mucosa leukoplakia with optical coherence tomography (OCT) method and pathological studies in 15 patients (9 females and 6 males aged 27—82). The study revealed specific OCT signs of leukoplakia: even disorder of tissue layering and less clear visualization of lamina propria. OCT is an important stage in the differential diagnosis of leukoplakia of the oral mucosa and significantly complements the clinical and pathomorphological study.

Keywords:

leukoplakia
optical coherence tomography
oral mucosa
pathological examination

Authors:

Semkin V.A.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Rabinovich O.F.

Otdelenie patologii slizistoĭ obolochki rta FGBU TsNIIS i ChLKh Minzdrava Rossii, Moskva

Agapitova L.P.

Central Research Institute of Stomatology and Maxillofacial Surgery Health Ministry, Moscow, Russia

Bezrukov A.A.

Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia

Babichenko I.I.

Russian University of People’s Friendship, Moscow, Russia, 117198

List of references:

  1. Babichenko II, Rabinovich OF, Ivina AA, Rabinovich IM, Togonidze AA. K voprosu o papillomavirusnom geneze lejkoplakii slizistoj obolochki rta. Arhiv patologii. 2014;1:32-36. (In Russ.)
  2. Barer GM, Volkov EA, Gemonov VV. i dr. Terapevticheskaya stomatologiya. Uchebnik. V 3 ch. Pod red. prof. Barera G.M. M.: GEOTAR-Media; 2005. (In Russ.)
  3. Mashkilleison AL. Predrak krasnoi kaimy gub i slizistoi obolochki rta. M.: Meditsina; 1970. (In Russ.)
  4. Rabinovich IM, Rabinovich OF, Ostrovski AD. New opportunities of the diagnostics of oral leukoplakia. Stomatologiia. 2007;37-40. (In Russ.)
  5. Rabinovich OF, Babichenko II, Rabinovich IM, Ostrovski AD, Togonidze AA. Improving diagnostics of leukoplakia. Stomatologiia. 2012;4:20-21. (In Russ.)
  6. Snopova LB. Morfologicheskaya ocenka slizistyx obolochek cheloveka metodom opticheskoj kogerentnoj tomografii: Dis... kand. med. nauk. M. 2010. (In Russ.)
  7. Togonidze AA. Optimizatsiya diagnostiki i lecheniya leikoplakii slizistoi obolochki rta: Dis... kand. med. nauk. M. 2015. (In Russ.) http://www.cniis.ru/downloads/dis/dis_Togonidze.pdf
  8. Amagasa T, Yamashiro M, Uzawa N. Oral premalignant lesions: from a clinical perspective. International Journal of Clinical Oncology. 2011;16(1):5-14. https://doi.org/10.1007/s10147-010-0157-3
  9. Bagan J, Scully C, Jimenez Y, Martorell M. Proliferative verrucous leukoplakia: a concise update. Oral Diseases. 2010;16(4):328-329. https://doi.org/10.1111/j.1601-0825.2009.01632.x
  10. Feller L, Altini M, Slabbert H. Pre-malignant lesions of the oral mucosa in a South African sample — a clinicopathological study. The Journal of the Dental Association of South Africa. 1991;46:5:261-265.
  11. Feller L, Lemmer J. Field cancerization and oral leukoplakia, in Field Cancerization: Basic Science and Clinical Aplications, G.D. Dakubo Ed. Nova Science, Ontario, Canada. 2011;95-111.
  12. Hube MA, Tantiwongkosi B. Oral and Oropharyngeal Cancer. Medical Clinics of North America. 2014;98(6):1299-1321.
  13. Barnes L, Eveson JW, Reichart P, Sidransky D. Pathology and genetics of head and neck tumours. 2005;56.

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