The interrelation between cerebral blood circulation and oral diseases as well as impact of prosthodontics treatment on cerebral hemodynamics was examined in the study. Cerebral hemodynamics was assessed by transcranial Doppler in 75 patients divided into three groups: (1) 30 patients with the initial form of vascular cerebral disorders (stage I-II); (2) 25 patients with severe vascular cerebral disorders (stage III); (3) 20 persons with no signs of encephalopathy as control group. Prosthodontic rehabilitation by full and partial teeth loss proved to contribute to normalization of indices of cerebral blood flow in patients with initial forms of cerebrovascular insufficiency (I and II stage of encephalopathy) and in patients with acute forms of insufficient brain blood supply (II and III stage of encephalopathy).