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Yarmolinskaya M.I.

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductive Medicine, St. Petersburg, Russia;
I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russia

Molotkov A.S.

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductive Medicine, St. Petersburg, Russia;
Saint Petersburg State University, Saint Petersburg, Russia

Tsybuk E.M.

Saint Petersburg State University, Saint Petersburg, Russia

Modern trends in the treatment of patients with endometriosis

Authors:

Yarmolinskaya M.I., Molotkov A.S., Tsybuk E.M.

More about the authors

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To cite this article:

Yarmolinskaya MI, Molotkov AS, Tsybuk EM. Modern trends in the treatment of patients with endometriosis. Russian Bulletin of Obstetrician-Gynecologist. 2026;26(1):110‑119. (In Russ.)
https://doi.org/10.17116/rosakush202626011110

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References:

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  2. Giudice LC, Oskotsky TT, Falako S, Opoku-Anane J, Sirota M. Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations. FASEB J. 2023;37:9:e23130. https://doi.org/10.1096/fj.202300907
  3. Bougie O, Yap MI, Sikora L, Flaxman T, Singh S. Influence of race/ethnicity on prevalence and presentation of endometriosis: a systematic review and meta-analysis. BJOG. 2019;126:9: 1104-1115. https://doi.org/10.1111/1471-0528.15692
  4. Simoens S, Dunselman G, Dirksen C, Hummelshoj L, Bokor A, Brandes I, Brodszky V, Canis M, Colombo GL, DeLeire T, Falcone T, Graham B, Halis G, Horne A, Kanj O, Kjer JJ, Kristensen J, Lebovic D, Mueller M, Vigano P, Wullschleger M, D’Hooghe T. The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres [published correction appears in Hum Reprod. 2014;29:9:2073]. Hum Reprod. 2012;27:5:1292—1299. https://doi.org/10.1093/humrep/des073
  5. Simoens S, Hummelshoj L, Dunselman G, Brandes I, Dirksen C, D’Hooghe T; EndoCost Consortium. Endometriosis cost assessment (the EndoCost study): a cost-of-illness study protocol. Gynecol Obstet Invest. 2011;71:3:170-176.  https://doi.org/10.1159/000316055
  6. Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility: a committee opinion. Fertil Steril. 2012;98:3:591-598.  https://doi.org/10.1016/j.fertnstert.2012.05.031
  7. Practice Committee of the American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis: a committee opinion [published correction appears in Fertil Steril. 2015;104:2:498]. Fertil Steril. 2014;101:4:927-935.  https://doi.org/10.1016/j.fertnstert.2014.02.012
  8. Endometriosis Guideline Development Group: Endometriosis. Guideline of European Society of Human Reproduction and Embryology. 2022.
  9. Brown J, Crawford TJ, Allen C, Hopewell S, Prentice A. Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Cochrane Database Syst Rev. 2017;1:1:CD004753. Published 2017. https://doi.org/10.1002/14651858.CD004753.pub4
  10. Niringiyumukiza JD, Cai H, Xiang W. Prostaglandin E2 involvement in mammalian female fertility: ovulation, fertilization, embryo development and early implantation. Reprod Biol Endocrinol. 2018;16:1:43.  https://doi.org/10.1186/s12958-018-0359-5
  11. Yarmolinskaya MI, Denisova VM. Modern approaches to the appointment of add-back therapy for patients with genital endometriosis. Effektivnaya farmakoterapiya. 2015;36:24-31. (In Russ.).
  12. Yarmolinskaya MI, Khachaturyan AR, Andreeva NYu, P’yankova VO. Current possibilities and prospects for the use of oral gonadotropin-releasing hormone antagonists (literature review). Problemy reproduktsii. 2020;26:5:78-83. (In Russ.). https://doi.org/10.17116/repro20202605178
  13. Carr B, Giudice L, Dmowski WP, O’Brien C, Jiang P, Burke J, Jimenez R, Hass S, Fuldeore M, Chwalisz K. Elagolix, an oral GnRH antagonist for endometriosis-associated pain: A Randomized controlled study. J Endometr Pelvic Pain Disord. 2013;5:3:105-115. 
  14. Bestel E, Humberstone A, Lecomte V, Loumaye E, Gotteland JP, Simon JA. The Effect of linzagolix on bone mineral density (BMD): Safety results from a dose-ranging trial [21J]. Obstetrics & Gynecology. 2019;133:112S-113S. https://doi.org/10.1097/01.AOG.0000558837.48634.b6
  15. Molotkov AS, Yarmolinskaya MI. Results of using an aromatase inhibitor in the treatment of patients with external genital endometriosis. Zhurnal akusherstva i zhenskikh boleznei. 2016; 65:56-57. (In Russ.).
  16. Yarmolinskaya MI, Molotkov AS, Bezhenar’ VF. Method for the complex treatment of external genital endometriosis. Patent for invention RU 2541089 C1, 10.02.2015. Demand No. 2013152127/15 dated 22.11.2013. (In Russ.).
  17. Endometriosis: diagnosis and management. London: National Institute for Health and Care Excellence (NICE); 2024, Nov 11. PMID 38815122.
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  19. Endometriosis: diagnostics, treatment and rehabilitation. Clinical recommendations. Moscow. 2016. (In Russ.). https://zdrav.spb.ru/media/filebrowser/%D1%8D%D0%BD%D0%B4%D0%BE%D0%BC%D0%B5%D1%82%D1%80%D0%B8%D0%BE%D0%B7_%D0%B4%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%C2%AD%D1%81%D1%82%D0%B8%D0%BA%D0%B0%2C_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5_%D0%B8_%D1%80%D0%B5%D0%B0%D0%B1%D0%B8%D0%BB%D0%B8%D1%82%D0%B0%D1%86%D0%B8%D1%8F.pdf
  20. Sukhikh GT, Serov VN, Adamyan LV, Baranov II, Bezhenar’ VF, Gabidullina RI, Dubrovina SO, Kozachenko AV, Podzolkova NM, Smetnik AA, Tapil’skaya NI, Uvarova EV, Shikh EV, Yarmolinskaya MI. Algorithms for managing patients with endometriosis: a consensus position of experts from the Russian Society of Obstetricians and Gynecologists. Akusherstvo i ginekologiya. 2023;5:159-176. (In Russ.). https://doi.org/10.18565/aig.2023.132
  21. Yarmolinskaya MI, Adamyan LV. Hormonal contraceptives and endometriosis: a modern view of the problem. Problemy reproduktsii. 2020;26:3:39-45. (In Russ.). https://doi.org/10.17116/repro20202603139
  22. Woman’s sterility: Clinical recommendations. Moscow. 2021. (In Russ.). https://roag-portal.ru/recommendations_gynecology
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