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Zarochentseva N.V.
Moscow Regional Research Institute of Obstetrics and Gynecology
Filonenko E.V.
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia
Baranov I.I.
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Rovinskaya O.V.
Moscow Regional Research Institute of Obstetrics and Gynecology
Trushina O.I.
P.A. Herzen Moscow Scientific Research Institute of Oncology
Novikova E.G.
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia
Fluorescence diagnostics and photodynamic therapy: prospects of application in gynecological and oncogynecological practice
Journal: Russian Bulletin of Obstetrician-Gynecologist. 2021;21(3): 37‑45
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To cite this article:
Zarochentseva NV, Filonenko EV, Baranov II, Rovinskaya OV, Trushina OI, Novikova EG. Fluorescence diagnostics and photodynamic therapy: prospects of application in gynecological and oncogynecological practice. Russian Bulletin of Obstetrician-Gynecologist.
2021;21(3):37‑45. (In Russ.)
https://doi.org/10.17116/rosakush20212103137
he review deals with the current understanding of the mechanisms of action of fluorescent diagnostics (FD) and photodynamic therapy (PDT) and the application of these methods in the treatment of cancer and precancerous diseases in gynecology. An overview of the most widely used photosensitizers in clinical oncology, as well as technical aspects of the use of laser radiation of various intensities, is presented. The results of studies on the use of PDT and PD with various photosensitizers in patients with gynecological and oncogynecological diseases are presented. Data on the effectiveness and safety of FD and PDT are presented. Organ preservation, selectivity, sparing effect and lack of need for anesthetic care indicate the relevance of these methods of treatment and prospects for intraepithelial neoplasia and precancerous diseases of the lower genital tract.
Keywords:
Authors:
Zarochentseva N.V.
Moscow Regional Research Institute of Obstetrics and Gynecology
Filonenko E.V.
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia
Baranov I.I.
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Rovinskaya O.V.
Moscow Regional Research Institute of Obstetrics and Gynecology
Trushina O.I.
P.A. Herzen Moscow Scientific Research Institute of Oncology
Novikova E.G.
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia
Received:
27.10.2020
Accepted:
10.11.2020
List of references:
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