Differential diagnosis of various forms of chronic rhinitis based on optical coherence tomography

Shakhova M.A.; Meller A.E.; Solov'ev N.A.; Terentyeva A.B.; Shakhov A.V.; Kurakina D.A.; Kirillin M.Iu.

doi:https://doi.org/10.17116/rosrino201927031127

Shakhova M.A.

Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russia, Nizhny Novgorod, Russia;
Federal Research Center 'Institute of Applied Physics' of the Russian Academy of Sciences, Nizhny Novgorod, Russia

Meller A.E.

Solov'ev N.A.

Tsentr éndokrinnoĭ khirurgii klinicheskoĭ bol'nitsy #83 FMBA Rossii;
laboratoriia minimal'no invazivnoĭ khirurgii NIMSI MGMSU, kafedra khirurgii, éndoskopii i anesteziologii IPK FMBA Rossii

Terentyeva A.B.

Federal State Budgetary Educational Institution of Higher Education 'Privolzhsky Research Medical University' of the Ministry of Health of the Russia, Nizhny Novgorod, Russia

Shakhov A.V.

Federal State Budgetary Educational Institution of Higher Education 'Privolzhsky Research Medical University' of the Ministry of Health of the Russia, Nizhny Novgorod, Russia

Kurakina D.A.

Federal Research Center 'Institute of Applied Physics' of the Russian Academy of Sciences, Nizhny Novgorod, Russia

Kirillin M.Iu.

Institut prikladnoĭ fiziki RAN, Nizhniĭ Novgorod

Differential diagnosis of various forms of chronic rhinitis based on optical coherence tomography

Authors:

Shakhova M.A., Meller A.E., Solov'ev N.A., Terentyeva A.B., Shakhov A.V., Kurakina D.A., Kirillin M.Iu.

More about the authors

Journal: Russian Rhinology. 2019;27(3): 127‑133

DOI: 10.17116/rosrino201927031127

Read: 1537 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Shakhova MA, Meller AE, Solov'ev NA, Terentyeva AB, Shakhov AV, Kurakina DA, Kirillin MIu. Differential diagnosis of various forms of chronic rhinitis based on optical coherence tomography. Russian Rhinology. 2019;27(3):127‑133. (In Russ.)
https://doi.org/10.17116/rosrino201927031127

Подписка 2026 Российская ринология (Russian Rhinology)

Использование инфографики авторами научных работ

Close metadata

Abstract:

Chronic Rhinitis (HR) is a common inflammatory disease that significantly affects the quality of life. Differential diagnostics of various forms of CV is complicated by the lack of objective safe methods based on morphological verification. The aim of our study was to show the possibility of optical coherence tomography (OCT) for differential diagnosis of various forms of chronic rhinitis (HR). The research was carried out on the basis of ENT clinic of SBUZ N.A. Semashko NSDC, N.Novgorod. With the help of OCT 51 patients aged 32 to 74 years were examined. The method of classification of diagnostic images of the nasal mucosa based on the approximation of the histogram of the image by the analytical function is proposed. It is shown that optical coherence tomography is capable of non-invasive real-time detection of morphofunctional features of the nasal cavity mucosa in normal and various inflammatory pathologies. Automated classification allows you to objectively interpret OCT images, providing 89% sensitivity of the method. Using the OCT method will improve the differential diagnosis of various forms of chronic rhinitis and optimize treatment tactics.

Keywords:

chronic rhinitis

atrophy

hypertrophy

differential diagnostics

optical coherence tomography

texture analysis

image classification

Authors:

Shakhova M.A.

Meller A.E.

Solov'ev N.A.

Tsentr éndokrinnoĭ khirurgii klinicheskoĭ bol'nitsy #83 FMBA Rossii;
laboratoriia minimal'no invazivnoĭ khirurgii NIMSI MGMSU, kafedra khirurgii, éndoskopii i anesteziologii IPK FMBA Rossii

Terentyeva A.B.

Federal State Budgetary Educational Institution of Higher Education 'Privolzhsky Research Medical University' of the Ministry of Health of the Russia, Nizhny Novgorod, Russia

Shakhov A.V.

Federal State Budgetary Educational Institution of Higher Education 'Privolzhsky Research Medical University' of the Ministry of Health of the Russia, Nizhny Novgorod, Russia

Kurakina D.A.

Federal Research Center 'Institute of Applied Physics' of the Russian Academy of Sciences, Nizhny Novgorod, Russia

Kirillin M.Iu.

Institut prikladnoĭ fiziki RAN, Nizhniĭ Novgorod

Close metadata

References:

Hellings PW, Klimek L, Cingi C, Agache I, Akdis C, Bachert C, Bousquet J, Demoly P, Gevaert P, Hox V, Hupin C, Kalogjera L, Manole F, Mösges R, Mullol J, Muluk NB, Muraro A, Papadopoulos N, Pawankar R, Rondon C, Rundenko M, Seys SF, Toskala E, Van Gerven L, Zhang L, Zhang N, Fokkens WJ. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2017;72(11):1657-1665. https://doi.org/10.1111/all.13200
Papadopoulos NG, Guibas GV. Rhinitis subtypes, endotypes, and definitions. Immunology and Allergy Clinics of North America. 2016;36(2):215-233. https://doi.org/10.1016/j.iac.2015.12.001
Bousquet J, Schünemann HJ, Samolinski B, Demoly P, Baena-Cagnani CE, Bachert C, Warner JO. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. Journal of Allergy and Clinical Immunology. 2012;130(5):1049-1062. https://doi.org/10.1016/j.jaci.2012.07.053
Valero A, Muñoz-Cano R, Sastre J, Navarro AM, Martí-Guadaño E, Dávila I, del Cuvillo A, Colás C, Antépara I, Izquierdo I, Mullol J. The impact of allergic rhinitis on symptoms, and quality of life using the new criterion of ARIA severity classification. Rhinology. 2012;50(1):33-36. https://doi.org/10.4193/Rhino11.071
Bousquet J, Fokkens W, Burney P, Durham SR, Bachert C, Akdis CA, Zock JP. Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper. Allergy. 2008;63(7):842-853. https://doi.org/10.1111/j.1398-9995.2008.01715.x
Settipane RA. Epidemiology of Vasomotor Rhinitis. World Allergy Organization Journal. 2009;2(6):115-118. https://doi.org/10.1097/WOX.0b013e3181ac91ae
Colás C, Brosa M, Antón E, Montoro J, Navarro A, Dordal MT, Dávila I, Fernández-Parra B, Ibáñez MDP, Lluch-Bernal M, Matheu V, Rondón C, Sánchez MC, Valero A, Rhinoconjunctivitis Committee of the Spanish Society of Allergy and Clinical Immunology. Estimate of the total costs of allergic rhinitis in specialized care based on real-world data: the FERIN Study. Allergy. 2017;72(6):959-966. https://doi.org/10.1111/all.13099
Bernstein JA. Allergic and mixed rhinitis: Epidemiology and natural history. Allergy and Asthma Proceedings. 2010;31(5):365-369. https://doi.org/10.2500/aap.2010.31.3380
Mølgaard E, Thomsen SF, Lund T, Pedersen L, Nolte H, Backer V. Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adults. Allergy. 2007;62(9):1033-1037. https://doi.org/10.1111/j.1398-9995.2007.01355.x
Mazowiecki EN, Baranov NP. Dynamics of forms of chronic rhinitis for 40 years. Rossijskaya Rinologiya. 2005;2:51. (In Russ.)
Astafieva NG, Udovichenko YeN, Gamova IV, Perfilova IA, Naumova OS, Kenesariyeva ZhM, Vachugova LK, Gapon MS. Allergic and non-allergic rhinitis: comparative characteristics. Lechashhij Vrach. 2013;4:10. (In Russ.)
Quan M, Casale TB, Blaiss MS. Should clinicians routinely determine rhinitis subtype on initial diagnosis and evaluation? A debate among experts. Clinical Cornerstone. 2009;9(3):54-60. https://doi.org/10.1016/S1098-3597(09)80014-8
Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, Williams D. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 (in collaboration with the World Health Organization, GA2LEN and AllerGen). Allergy. 2008;63:8-160. https://doi.org/10.1111/j.1398-9995.2007.01620.x
Reshetnikova OV. Differential diagnosis of chronic rhinitis: a review and analysis of the methods. Rossijskaya Rinologiya. 2013;21(4):25-30. (In Russ.)
Yunusov AS, Serebryakova IYu. The method of differential diagnosis of rhinitis. Patent RUS №2232548/20.07.04. Bull. №20. (In Russ.). https://patents.s3.yandex.net/RU2232548C2_20040720.pdf
Serebryakova IYu. Differencial’naya diagnostika gipertrofii nizhnej nosovoj rakoviny’ i pokazaniya k shhadyashhej e’ndonazal’noj xirurgii: Dis... kand. med. nauk. M. 2005. (In Russ.)
Romano FR, Voegels RL, Goto EY, Prado FA, Butugan O. Nasal contact endoscopy for the in vivo diagnosis of inverted schneiderian papilloma and unilateral inflammatory nasal polyps. American Journal of Rhinology. 2007;21(2):137-144. https://doi.org/10.2500/air.2007.21.3003
Khorolskaya MA, Vakhrushev SG, Terskova NV. Contact microendoscopy in the differential diagnosis of chronic rhinitis. Rossijskaya Otorinolaringologiya. 2010;6(49):61-66. (In Russ.)
Rubinstein M, Fine EL, Sepehr A, Armstrong WB, Crumley RL, Kim JH, Chen Z, Wong BJ Optical Coherence Tomography of the Larynx Using the Niris System. Journal of Otolaryngology — Head & Neck Surgery. 2010;39(2):150-156.
Meller AE, Motovilova TM, Panteleeva OG, Kuznetsov SS, Stroykova KI, Kondratieva OA, Kirillin MYu, Shakhova NM. Non-invasive diagnosis of non-tumor pathology using optical coherence tomography. Al’manax Klinicheskoj Mediciny. 2016;44(2):203-212. (In Russ.) https://doi.org/10.18786/2072-0505-2016-44-2-203-212
Kirillin MYu, Shakhova NM, Panteleeva OG, Yunusova E, Donchenko E. Criteria for pathology recognition in optical coherence tomography of fallopian tubes. Journal of Biomedical Optics. 2012;17(8):081413. https://doi.org/10.1117/1.JBO.17.8.081413
Meller A, Shakhova M, Rilkin Y, Novozhilov A,Kirillin M, Shakhov A. Optical coherence tomography in diagnosing inflammatory diseases of ENT. Photonics & Lasers in Medicine. 2014;3(4):323-330. https://doi.org/10.1515/plm-2014-0025
Kirillin MYu, Farhat G, Sergeeva EA, Kolios MC, Vitkin A. Speckle statistics in OCT images: Monte Carlo simulations and experimental studies. Optics Letters. 2014;39(12):3472-3475. https://doi.org/10.1364/OL.39.003472