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Khovasova N.O.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Vorobyeva N.M.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Tkacheva O.N.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Naumov A.V.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Malaya I.P.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Kotovskaya Yu.V.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Results of comprehensive geriatric evaluation in outpatients over 65 years old depending on the presence of anemia. Subanalysis of the EVKALIPT study

Authors:

Khovasova N.O., Vorobyeva N.M., Tkacheva O.N., Naumov A.V., Malaya I.P., Kotovskaya Yu.V.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2025;28(9): 101‑111

DOI: 10.17116/profmed202528091101

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Table of contents

RESULTS OF COMPREHENSIVE GERIATRIC EVALUATION IN OUTPATIENTS OVER 65 YEARS OLD DEPENDING ON THE PRESENCE OF ANEMIA. SUBANALYSIS OF THE EVKALIPT STUDY
RESULTS OF COMPREHENSIVE GERIATRIC EVALUATION IN OUTPATIENTS OVER 65 YEARS OLD DEPENDING ON THE PRESENCE OF ANEMIA. SUBANALYSIS OF THE EVKALIPT STUDY

To cite this article:

Khovasova NO, Vorobyeva NM, Tkacheva ON, Naumov AV, Malaya IP, Kotovskaya YuV. Results of comprehensive geriatric evaluation in outpatients over 65 years old depending on the presence of anemia. Subanalysis of the EVKALIPT study. Russian Journal of Preventive Medicine. 2025;28(9):101‑111. (In Russ.)
https://doi.org/10.17116/profmed202528091101

 
Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To compare the results of a comprehensive geriatric assessment in outpatients aged 65 and over with the presence or absence of anemia.

MATERIALS AND METHODS

The results of subanalysis of the EVKALIPT multicenter cross-sectional trial, in which 2547 outpatient patients (32% of them — men) aged 65 years and over (median — 77 years) took part, were presented. All participants underwent a comprehensive geriatric evaluation according to the conventional procedure. Anemia was diagnosed at hemoglobin level below 130 g/l in men and below 120 g/l in women.

RESULTS

Incidence rate of anemia amounted to 18.7%. A comprehensive geriatric assessment showed that patients with anemia have worse physical and mental health, lower physical and functional activity and education level. Patients with anemia are more comorbid, more often have I disability group. The presence of anemia in outpatient elderly patients increases the chances of detecting a number of geriatric syndromes (senile asthenia, cognitive disorders, depression, basic and instrumental dependence in everyday life, hearing impairment, falls, sarcopenia, malnutrition) by 1.3—3.4 times according to the data of univariate regression analysis.

Multivariate regression analysis has shown that cognitive disorders (odds ratio (OR) 1.33; 95% confidence interval (CI) 1.04—1.71; p=0.024), hearing impairment (OR 1.46; 95% CI 1.04—2.05; p=0.027), instrumental dependence in everyday life (OR 1.83; 95% CI 1.44—2.34; p<0.001) and malnutrition (OR 2.37; 95% CI 1.45—3.88; p=0.001) are independently associated with anemia in outpatients aged 65 years and over.

CONCLUSION

Outpatients with anemia aged 65 years and over have the worst geriatric status compared to the ones without anemia.

Keywords:

anemia
elderly age
outpatients
comprehensive geriatric evaluation
geriatric syndromes
geriatric status

Authors:

Khovasova N.O.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Vorobyeva N.M.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Tkacheva O.N.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Naumov A.V.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University;
Institute of Continuing Education and Professional Development of the Pirogov Russian National Research Medical University (Pirogov University)

Malaya I.P.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Kotovskaya Yu.V.

Russian Clinical and Research Center of Gerontology — Pirogov Russian National Research Medical University

Received:

04.08.2025

Accepted:

02.09.2025

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