OBJECTIVE
To study the possibility of assessing cardiovascular risk through the use of integral analysis of vital functions.
MATERIALS AND METHODS
A cross-sectional study, that included 1190 patients undergoing periodic health check-ups, was carried out. Integral analysis of vital functions (VFs) consisted in evaluation of VFs integral parameters, namely autonomic nervous system and haemodynamics. Level of psychological stress was measured on the PSM-25 scale. A number of patients equal 865 was selected at the first stage by exclusion criteria, who were divided into 2 groups according to the scales of cardiovascular risk (CVR) used for examination: the 1st group — patients under 40 years old, CVR evaluation on the relative risk scale for individuals under 40 years old, the 2nd group — patients aged 40 years and older, CVR evaluation using the SCORE2, SCORE2-OR scales. All patients (1190) were divided into 3 groups at the second stage according to the application of 10-year cardiovascular risk global assessment scale: group A — low and moderate CVR, group B — high CVR, group C — very high CVR. Correlation relationships were determined in all five groups between value of CVR and values of VFs integral indicators and the PSM-25 scale.
RESULTS
Significant correlation relationships between CVR and studied indicators, presented in the descending order of importance, have been identified: stress resistance index (SRI), sympathetic activity index (SAI), Baevsky stress index (BSI), integral balance (IB), adaptive reserve (AR), PSM-25. Statistically significant differences of the following indicators’ median have been revealed in groups A, B, C: SRIC<SRIB<SRIA, SAIA<SAIB<SAIC, BSIA<BSIB<BSIC, IBB<IBA, IBC<IBA, ARC<ARA. The median of all studied indicators was within normal range in group A, the medians of autonomic nervous system indicators were higher than normal in groups B and C, the median of SRI was lower than normal in group C.
CONCLUSION
It has been proven that evaluation of cardiovascular risk can be performed using some integral indicators of vital functions, the best of which is stress resistance index.
