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Marchenkova L.A.

Moskovskiĭ oblastnoĭ nauchno-issledovatel'skiĭ klinicheskiĭ institut im. M.F. Vladimirskogo

Makarova E.V.

Moscow State University of Medicine and Dentistry named after AI Evdokimov, Moscow, Russia, 127473

Benefits of combined calcium and vitamin D in the prevention and treatment of osteoporosis: Renaissance of the paradigm

Authors:

Marchenkova L.A., Makarova E.V.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2017;20(4): 57‑62

DOI: 10.17116/profmed201720457-62

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BENEFITS OF COMBINED CALCIUM AND VITAMIN D IN THE PREVENTION AND TREATMENT OF OSTEOPOROSIS: RENAISSANCE OF THE PARADIGM
BENEFITS OF COMBINED CALCIUM AND VITAMIN D IN THE PREVENTION AND TREATMENT OF OSTEOPOROSIS: RENAISSANCE OF THE PARADIGM

To cite this article:

Marchenkova LA, Makarova EV. Benefits of combined calcium and vitamin D in the prevention and treatment of osteoporosis: Renaissance of the paradigm. Russian Journal of Preventive Medicine. 2017;20(4):57‑62. (In Russ.)
https://doi.org/10.17116/profmed201720457-62

 
 
Подписка 2025-2 (Russian Journal of Preventive Medicine)
 
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Despite the fact that calcium and vitamin D are widely represented on the pharmaceutical market, actively prescribed by physicians, and used by the population, there are still a lot of questions, uncertainty and doubts among physicians and patients regarding the benefits of these agents, harm, rational combination and dosage. This review considers the causes of calcium and vitamin D deficiency and data on its prevalence in different age groups; it presents the optimal doses of calcium and vitamin D for the prevention of bone loss, fractures, and falls. Randomized clinical trials and metaanalyses demonstrate that combined calcium and vitamin D intake significantly and more effectively slows down bone loss and reduces the risk of fractures and falls than monotherapy with these agents. In addition to its impact on the musculoskeletal system, calcium and vitamin D supplementation contributes to the prevention of cardiovascular diseases and cancer and shows good tolerability.

Keywords:

calcium
vitamin D deficiency
osteoporosis
postmenopause

Authors:

Marchenkova L.A.

Moskovskiĭ oblastnoĭ nauchno-issledovatel'skiĭ klinicheskiĭ institut im. M.F. Vladimirskogo

Makarova E.V.

Moscow State University of Medicine and Dentistry named after AI Evdokimov, Moscow, Russia, 127473

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