Stroke is one of the leading global causes of death. To seek timely medical care and to prevent successfully stroke, patients should be aware of its risk factors (hypertension, diabetes mellitus, atrial fibrillation, hypercholesterolemia, smoking, overweight, low physical activity, poor diet, etc.) and warning signs (sudden weakness or numbness, dizziness, dysphasia, ataxia, etc.). The purpose of this systematic review was to assess the data available in the literature on public awareness of the stroke risk factors and warning signs, which ensure that a gender analysis may be carried out. The review includes the data of Russian and foreign studies demonstrating low public awareness. Both strategies for the modification of behavioral stereotypes in people at high risk for stroke and those for its population-wide prevention are needed to reduce the incidence of the condition within the framework of its primary prevention. Besides both individual and population-wide approaches to preventing stroke, gender-specific educational campaigns using different information sources (mass media, printed matter, lectures, and educational movies) should be also used as additional means of increasing the awareness of this condition. Each of the presented programs has its own advantages and disadvantages and differs in the size of the target population, the type of the information presented, the volume of educational information, and the need for staff availability. A wide variety of methods to provide information to the population makes possible stroke control programs that meet the set objectives and available resources.