Mechanisms of reduction in coronary heart disease mortality in different countries of the world

Boytsov S.A.

doi:https://doi.org/

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Abstract:

The paper considers the mechanisms of change in coronary heart disease (CHD) mortality as a prerequisite for selecting the right course of action for its reduction. There are currently more than 40 different models for the retrospective study of the mechanisms of change in CHD mortality. The performed analysis has shown that the reduction in the prevalence and magnitude of risk factors for non-communicable diseases makes the greatest contribution to the decline of CHD deaths in most populations. The increasing prevalence of obesity, physical inactivity, and diabetes mellitus substantially reduces the cumulative positive effect, but the considerable reduction of risk factors, such as hypertension, hypercholesterolemia, and smoking, in combination with therapeutic measures can still maintain the overall trend in lower mortality rates. As the risk factors are considerably reduced and more effective treatments (mainly with statins) are promoted, there may be a relative rise in the role of a therapeutic factor. If there is a tendency towards a higher prevalence of risk factors, the current therapeutic measures are unable to prevent the rise of CHD deaths. The Russian Federation still shows an inadequate rate of CHD mortality decline, which is chiefly a result of the high prevalence of risk factors for non- communicable diseases.

Keywords:

risk factors

cardiovascular diseases

coronary heart disease

mortality

primary prevention

secondary prevention

Authors:

Boytsov S.A.

National Research Centre for Preventive Medicine, Moscow, Russia

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References:

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