The purpose of the study is to summarize and analyze foreign literature devoted to the study of the effect of di-isononyl phthalate (DINP) on the reproductive function of humans and animals. In recent years, the production and use of DINP has increased, which is accompanied by an increased risk of exposure to humans, which is reflected in a rapid increase in the concentration of DINP metabolites found in human biological samples. Based on these studies, neither pre- nor perinatal exposure to DINP has a significant effect on female reproduction. However, exposure to adults has some negative effect on reproductive parameters in rodent models. Even short-term exposure to DINP led to lifelong consequences. On the contrary, in humans, the question of whether short-term exposure to DINP will lead to similar consequences requires further study. Based on limited information, we know that women with higher concentrations of DINP in the blood increased the time needed to start pregnancy. Many questions have yet to be answered, for example, whether there is a relationship between exposure to DINP and pregnancy loss. Moreover, the exact mechanism of the effect of DINP on the reproductive organs is also unclear and needs further study. Studies on male animals have shown that DINP has an antiandrogenic effect. Human studies also show that exposure to DINP can lead to changes in sex hormone levels and sperm quality. To date, some of the consequences of the DINP are still controversial. While the negative effects of DINP on males in animal models have been confirmed and are dose-dependent, the negative effects in humans have not yet been elucidated. Further studies are needed to assess the effects of exposure to DINP on adult men. In addition, it is necessary to determine the molecular mechanisms by which DINP acts on the reproductive organs of men.