The efficiency of in vitro fertilization program in patients with HPV infection

Zarochentseva N.V.

Moscow Regional Research Institute of Obstetrics and Gynecology

Krasnopol’skaya K.V.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology;
M.F. Vladimirsky Moscow Regional Clinical Research Institute;
Prior Reproductive Health Clinic

ORCID: 0000-0002-1275-9220

Isakova K.M.

State budgetary institution of health care Moscow Region «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Bashankaeva Yu.N.

Moscow Regional Research Institute of Obstetrics and Gynecology

The efficiency of in vitro fertilization program in patients with HPV infection

Authors:

Zarochentseva N.V., Krasnopol’skaya K.V., Isakova K.M., Bashankaeva Yu.N.

More about the authors

Journal: Russian Journal of Human Reproduction. 2021;27(4): 108‑116

DOI: 10.17116/repro202127041108

Downloaded: 49

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To cite this article:

Zarochentseva NV, Krasnopol’skaya KV, Isakova KM, Bashankaeva YuN. The efficiency of in vitro fertilization program in patients with HPV infection. Russian Journal of Human Reproduction. 2021;27(4):108‑116. (In Russ.)
https://doi.org/10.17116/repro202127041108

Подписка 2025-2 (Russian Journal of Human Reproduction)

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BACKGRAUND

The problem of infertile marriage is extremely urgent, the frequency of infertility in the world is steadily growing. The causes of the problem vary and are actively studied, infection of the pelvic organs plays an important role in infertility. Recently, numerous studies demonstrating the negative impact of HPV infection on reproductive health have been published.

OBJECTIVE

The aim of the study was to study the effectiveness of IVF programs in patients with persistent HPV infection and without it.

MATERIALS AND METHODS

The study included clinical data of 137 infertile patients who applied for treatment in the ART and PE program from 2017 to 2020. Two groups of patients were formed. The results of infertility treatment were compared depending on the presence of human papillomavirus infection.

RESULTS

The number of aspirated oocytes and the percentage of fertilization in the groups did not differ significantly. The number of embryos obtained on day 5 and the number of good quality embryos are statistically significantly higher in the group without HPV. The percentage of blastocyst release in the groups is comparable, and the frequency of implantation is 1.5 times more frequent in the group without HPV. The frequency of pregnancy during embryo transfer is 1.5 times more frequent in patients of group II (p <0.05).

CONCLUSIONS

Persistent HPV infection can have a negative role in the outcome of ART programs, as well as reduce pregnancy rates.

Keywords:

HPV infection

IVF

ICSI

clinical pregnancy rate

reproductive outcomes

Authors:

Zarochentseva N.V.

Moscow Regional Research Institute of Obstetrics and Gynecology

Krasnopol’skaya K.V.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology;
M.F. Vladimirsky Moscow Regional Clinical Research Institute;
Prior Reproductive Health Clinic

ORCID: 0000-0002-1275-9220

Isakova K.M.

State budgetary institution of health care Moscow Region «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Bashankaeva Yu.N.

Moscow Regional Research Institute of Obstetrics and Gynecology

Received:

06.07.2021

Accepted:

10.07.2021

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