The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Kolesnikova L.V.

FGBU "Rostovskiĭ NII akusherstva i pediatrii" Minzdravsotsrazvitiia Rossii, Rostov-na-Donu

Ermolova N.V.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

Linde V.A.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

Markaryan I.V.

FSBI «Rostov Scientific and Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of Russia, Rostov-on-Don, Russia, 344012

Avanesova T.G.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

The experience of Visanne use in patients of reproductive age with external genital endometriosis

Authors:

Kolesnikova L.V., Ermolova N.V., Linde V.A., Markaryan I.V., Avanesova T.G.

More about the authors

Journal: Russian Journal of Human Reproduction. 2016;22(3): 101‑106

DOI: 10.17116/repro2016223101-106

Read: 20744 times

Download PDF (RU)
Contact the author
Table of contents

THE EXPERIENCE OF VISANNE USE IN PATIENTS OF REPRODUCTIVE AGE WITH EXTERNAL GENITAL ENDOMETRIOSIS
THE EXPERIENCE OF VISANNE USE IN PATIENTS OF REPRODUCTIVE AGE WITH EXTERNAL GENITAL ENDOMETRIOSIS

To cite this article:

Kolesnikova LV, Ermolova NV, Linde VA, Markaryan IV, Avanesova TG. The experience of Visanne use in patients of reproductive age with external genital endometriosis. Russian Journal of Human Reproduction. 2016;22(3):101‑106. (In Russ.)
https://doi.org/10.17116/repro2016223101-106

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
The role of systemic and local immu­nity in the pathogenesis of endo­metriosis of varying degrees of prevalence of the process: a modern view. Russian Journal of Human Reproduction. 2024;(5):6-14
The role of ferroptosis in reproduction. A modern view of the problem. Russian Journal of Human Reproduction. 2024;(5):35-45
The influence of endo­metriosis on the quality of life and reproductive function of modern woman. Russian Journal of Human Reproduction. 2024;(5):101-107
Effi­ciency of using dienogest at the stage of pregravid preparation on the course of pregnancy and the outcome of childbirth in patients with endo­metriosis. Russian Journal of Human Reproduction. 2024;(5):118-125
Factors affe­cting the quality of life of patients with neurological mani­festations of post-COVID syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):44-50
Application of fillers for inti­mate contour plasty in aesthetic gyne­cology. Russian Bulletin of Obstetrician-Gynecologist. 2024;(5):58-65
Quality of life and psychosomatic status of women of reproductive age with adenomyosis. Russian Bulletin of Obstetrician-Gynecologist. 2024;(5):83-89
Evaluation of blepharoplasty outcomes using psychometric scales. Plastic Surgery and Aesthetic Medi­cine. 2024;(4-2):72-79
Effi­ciency of complex medi­cal reha­bilitation after pulmonary enda­rterectomy. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;(6):629-636
Simu­ltaneous auto­plastic repair and diastasis recti correction for linea alba hernias. Russian Journal of Evidence-Based Gastroenterology. 2024;(4):34-39
Abstract:

Objective - to assess the influence of endometriosis treatment with dienogest 2 mg per day on the life quality parameters. Material and methods. The study involved 74 patients of reproductive age with pain syndrome and endometriosis. The results were assessed in 3-6-12 months after the treatment (surgical and medical treatment with the dienogest). Results. Such a symptom as dysmenorrhea was treated in 100% of cases in the postoperative period in patients using Visanne. The pain syndrome disappeared in 70% of patients and in 30 and 100% there was significant relief of symptoms in 3 and 6 months respectively. No sonographic signs of disease recurrence were found in the postoperative period in 3, 6 and 12 months of treatment with dienogest. Also there was no any adverse effect of Visanne on bloodlipids and liver enzymes. Conclusions. It has been found that Visanne (dienogest) is a highly effective medicine for treatment of patients with endometriosis of different stages. It eliminate the pain syndrome and reduces the blood loss, it has a low adverse side effects rate and it has an excellent tolerability and safety, which improves the life quality of patients with endometriosis.

Keywords:

endometriosis
quality of life
pain syndrome
dienogest
bloodlipids

Authors:

Kolesnikova L.V.

FGBU "Rostovskiĭ NII akusherstva i pediatrii" Minzdravsotsrazvitiia Rossii, Rostov-na-Donu

Ermolova N.V.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

Linde V.A.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

Markaryan I.V.

FSBI «Rostov Scientific and Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of Russia, Rostov-on-Don, Russia, 344012

Avanesova T.G.

Federal State Budgetary Institution «Rostov Scientific-Research Institute of Obstetrics and Pediatrics» of the Ministry of Health of the Russia, Rostov-on-Don, Russia, 344012

Close metadata

References:

  1. Adamyan LV, Sonova MM, Tikhonova ES, Antonova SO. Medical and social aspects of endometriosis. Problemy reprduktsii. 2011;6:78-81. (In Russ.).
  2. Guidice LC. Endometriosis, N NEJM. 2010;362:2389-2398. doi: 10.1056/NEJMcp1000274
  3. Adamyan LV, Osipova AA, Sonova MM. Evolution of hormone therapy for endometriosis. Problemy reprduktsii.2006;5:11-16. (In Russ.).
  4. Kira EF, Ermolinskii EE, Mel'ko AI. Endometrioddisease. Modern principles of treatment. Ginekologiya. 2004;5:231-237. (In Russ.).
  5. Vercellini P, Grosignani PG, Abbiati A, et al. The effect of surgery for symptomatic endometriosis: the other side of the story. Human Reproduction. 2009;15:177-188.  doi: 10.1093/humupd/dmn062
  6. Falcone T, Lebovic DI. Clinical management of endometriosis. Obstetrical and Gynecological Survey. 2011;118(3):691-705.  doi: 10.1097/AOG.0b013e31822adfd1
  7. Burlev VA, Shorokhova MA, Samoilova TE. Modern principles of pathogenetic treatment of endometriosis. Consilium Medicum. 2007;9(6):8-12. (In Russ.).
  8. Shorokhova MA, Burlev VA, Samoilova TE. Pathogenetic substantiation of modern principles of treatment of patients with endometriosis: the pros and cons. Rossiisikii vestnik akushera-ginekologa. 2008;8(4):23-30. (In Russ.).
  9. Sol'skii SYa, Sol'skii VS. Features of the effectiveness of the combined treatment of external genital endometriosis. Zhurnal akusherstva i zhenskikh bolznei. 2009;58(5):79. (In Russ.).
  10. Radzinskii VE, Khamoshina MB. Endometriosis: to treat or not to treat, and if so, what. Farmateka. 2009;9(183):64-67. (In Russ.).
  11. Pavlov RV, Sel'kov SA, Pydra AR, Kundokhova MS. Use of roncoleukin in the treatment of external genital endometriosis. Paper presented at: XI All-Russian Scientific Forum "Mother and Child". 28 September - 1 October. M. 2010 (In Russ.). Available at: http://ncagip.ru/for-experts/seminars/archive/1337.html Accessed May 02, 2016
  12. Malyshkina AI, Sotnikova NYu, Antsiferova YuS. Immunomodulators in the treatment of external genital endometriosis. Paper presented at: XI All-Russian Scientific Forum "Mother and Child". 28 September - 1 October. M. 2010 (In Russ.). Available at: http://ncagip.ru/for-experts/seminars/archive/1337.html Accessed May 02, 2016
  13. Sonova MM, Arslanyank N, Loginova ON, Maksimova YuV, Murdalova ZKh, Shulyak IYu. Optimization of treatment of external genital endometriosis with the use of antioxidant agents. Paper presented at: XXIII International Congress with a course of endoscopy. June 8-10. M. 2010 (In Russ.).
  14. Yarmolinskaya MI, Shved NYu, Ivashchenko TE, Baranov VS, Sel'kov SA. The value of the genetic and immunological factors in the pathogenesis of endometriosis treatment. Paper presented at: XI All-Russian Scientific Forum "Mother and Child". 28 September - 1 October. M. 2010. (In Russ.). Available at: http://ncagip.ru/for-experts/seminars/archive/1337.html Accessed May 02, 2016
  15. ACOG Education Pamplet Ap013: Endometriosis. Washington, DC. American College of Obstetricians and Gynecologists. 2008;ISSN1074-8601.
  16. Vercellini P, Grosignani PG, Somegliana E, et al. Waiting for Go dot: a commonsens approach to the medical treatment of endometriosis. Human Reproduction. 2011;26:3-13.  doi: 10.1093/humrep/deq302
  17. Kennedy S, Bergqvist A, Chapron C, D'Hooghe T, Dunselman G, Greb R, et al. ESHRE guideline for the diagnosis and treatment of endometriosis. Human Reproduction. 2005;20:2698-2704. doi: 10.1093/humrep/dei135
  18. Al Kadri H, Hassan S, Al-Fozan HM, Hajeer A. Hormone therapy for endometriosis and surgical menopause. Cochrane Database System Review. 2009. doi: 10.1002/14651858.CD005997.pub2
  19. Leyland N, Casper R, Laberge Ph, et al. Endometriosis: Diagnosis and Management. Clinical Practice guideline. JOGC. 2010;32(7):1-27.
  20. Mikhnina EA, Davydova NI, Kalinina NM, Ellinidi VN. Hormonal and immunological disorders in the formation of endometrial pathology in women with external genital endometriosis. Zhurnal akusherstva i zhenskikh boleznei. 2006;55(4):87-100. (In Russ.).
  21. Hughes E, Brown J, Collins JJ, Farquhar C, Fedorkow DM, Vandekerckhove P. Ovulation suppression for endometriosis. Cochrane Database System Review. 2007;3.  doi: 10.1002/14651858.CD000155.pub2
  22. Harada T, Momoeda M, Taketani Y, Aso T, et al. Dienogest is as effective as intranasal busereline acetate for the relief of pain symptoms associated with endometriosis - a randomized, double-blind, multicenter, controlled trail. Fertility and Sterility. 2009;91(3):675-681.  doi: 10.1016/j.fertnstert.2007.12.080
  23. Schindler AE, Campanglnoli C, Druckmann R, et al. Classification and pharmacology of progestagens. Maturitas. 2008;81:171-180.  doi: 10.1016/j.maturitas.2003.09.014
  24. Sonova MM. Clinico-morphological, molecular biological and medical factors of genital endometriosis [dissertation]. M.: MSMSU. 2009. (In Russ.). Available at: http://www.dslib.net/ginekologia/kliniko-morfologicheskie-molekuljarno-biologicheskie-i-lechebnye-faktory-genitalnogo.html Accessed May 02, 2016
  25. Maksimova YuV. Clinico-morphological characteristic changes eutopic and ectopic endometrium with common forms of endometriosis [dissertation]. M.: MSMSU. 2010. (In Russ.). Available at: www.msmsu.ru/userdata/manual/doc/avtoref/2010_12/maksimova_12_10.doc Accessed 05.02.2016
  26. Serracchioli R, Mabrouk M, Frasca C. Long-term cyclic and continuous oral contraceptive therapy aтd endometrioma recurrence: a randomized, controlled trail. Fertility and Sterility. 2010;93:52-56.  doi: 10.1016/j.fertnstert.2008.09.052
  27. Bedaiwy MA. Long-term management of endometriosis: Medical therapy and treatment of infertility. SRM. 2011;8(3):10-14.  doi: 10.1016/j.mefs.2011.06.001
  28. Sasagawa S, Shimizi Y, Kami H, Takeuchi T, et al. Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile. Steroids. 2008;73:222-231.  doi: 10.1016/j.steroids.2007.10.003
  29. Kipping C, Duijkers I, Faustman TE, et al. Pharmacodynamic study of four oral dosages of dienogest. Fertility and Sterility. 2010;94:181.  doi: 10.1016/j.fertnstert.2010.07.708
  30. Harada M, Osuga Y, Izumi G, Takamura M, et al. Dienogest, a new conservative strategy for extragenital endometriosis: a pilot study. Gynecological Endocrinology. 2011;27(9):1-4.  doi: 10.3109/09513590.2010.533800
  31. Bulun SE, Cheng YH, Yin P, Imir G, Utsunomiya H, Attar E, et al. Progesterone résistance in endometriosis: link to failure to metabolize estradiol. Molecular and Cellular Endocrinology. 2006;248:94-103.  doi: 10.1016/j.mce.2005.11.041
  32. Sitruk-Ware R. New progestagens for contraceptive use. Human Reproduction. 2006;12(2):169-178.  doi: 10.1093/humupd/dmi046
  33. Fu L, Osuga Y, Morimoto C, et al. Dienigest inhibits BrdU uptake wuth G0/G1 arrest in cultured endometriotic stromal cells. Fertility and Sterility. 2008;89:1344-1347. doi: 10.1016/j.fertnstert.2007.03.042
  34. Shimizu Y, Takeuchi T, Mita S, et al. Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human ehdometrial cells with suppression of cyclin DI gene expression. Molecular Human Reproduction. 2009;15:693-701.  doi: 10.1093/molehr/gap042
  35. Mueck A, Seeger H, Buhlihg KJ. Why use dienogest for the first contraceptive pill with estradiol. Gynecological Endocrinology. 2010;26(2):109-113.  doi: 10.3109/09513590903184167
  36. Schindler AE, Henkel A, Moore C, Oettel M. Effect and safety of high-dose dienogest (20 mg/day) in the treatment of women with endometriosis. Acta Obstetricia et Gynecologica Scandinavica. 2010;282(5):507-514.  doi: 10.1007/s00404-009-1301-z
  37. Katayama H, Katayama T, Uematsu K, et al. Effect of dienogest administration on angiogenesis and hemodinamics in a rat endometrial autograph model. Human Reproduction. 2010;25(11):2851-2858. doi: 10.1093/humrep/deq241
  38. Petraglia F, Hornung D, Seitz C, et al. Reduced pelvic pain in women with endometriosis: efficacy of lohg-term dienogest treatment. Acta Obstetricia et Gynecologica Scandinavica. 2012;285(1);167-173.  doi: 10.1007/s00404-011-1941-7
  39. Momoeda M, Harada T, Terakawa N, et al. Long-term use of dienogest for the treatment of endometriosis. Journal of Obstetrics and Gynaecology Research. 2009;35(6):1069-1076. doi: 10.1111/j.1447-0756.2009.01076.x
  40. Cosson M, Querleu D, Donnez J, et al. Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery: results of a prospective, multicenter, randomized study. Fertility and Sterility. 2002;7(4):684-692.  doi: 10.1016/S0015-0282(01)03270-8 
  41. Gerasimov AM, Kulida LV, Brykin NS, Gorta RN. Influence of dienogest on morphofunctional condition of the endometrium for external genital endometriosis. Ginekologiya. 2014;3:10-13. (In Russ.).
  42. Sinaii N, Cleary SD, Yones N, Ballweg ML, Stratton H. Treatment utilizathion for endometriosis symptoms: a cross-sectional survey study of lifetime experience. Fertility and Sterility. 2007;87(6):1277-1286. doi: 10.1016/j.fertnstert.2006.11.051
  43. Somigliana E, Vigano P, Barbara G, Vercellini P. Treatment of endometriosis-related pain: options and outcomes. Frontiersin Bioscience. 2009;1:455-465. https://www.bioscience.org/new-archive-pages
  44. Ermolova NV. Pathogenic mechanisms of external genital endometriosis and its stages in patients of reproductive age [dissertation]. Rostov-on-Don: Rostov State Medical University. 2009. (In Russ.). Available at: http://dissovet.rostgmu.ru Accessed 05.02.2016
  45. Kbhler G, Goretzlehner G, Brachmann K. Lipid metabolism during treatment of endometriosis with the progestin dienogest. Acta Obstetricia et Gynecologica Scandinavica. 1989;68(7):633-635.  doi: 10.3109/00016348909013283
  46. Strowitzki T, Faustmann T, Gerlinger C, Seitz C. Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2010;151(2):193-198.  doi: 10.1016/j.ejogrb.2010.04.002 
  47. Strowitzki T, Marr J, Gerlinger C, Seitz C. Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trail. Human Reproduction. 2010;25(3):633-641.  doi: 10.1093/humrep/dep469
  48. Karakhalis LYu, Zhigalenko AR. Experienceintheuseofdienogest 2 mg (Visan) inKrasnodarKraipatients. Problemy reprduktsii. 2012;5:41-44. (In Russ.).
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.