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Adamyan L.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Burgova E.N.

Institut khimicheskoĭ fiziki im. N.I. Semenova RAN, Moskva

Serezhenkov V.A.

Institut khimicheskoĭ fiziki im. N.I. Semenova RAN, Moskva

Sonova M.M.

Kafedra reproduktivnoĭ meditsiny i khirurgii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta

Tikhonova E.S.

Kafedra reproduktivnoĭ meditsiny i khirurgii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta

Laskevich A.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Shamugia N.M.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Vanin A.F.

Semenov institute of chemical physics of the Russian academy of sciences, Moscow, Russia;
Institute for regenerative medicine, Sechenov First Moscow State Medical University, Moscow, Russia

The alteration of lactoferrin active center structure in peritoneal liquid of patients with endometriosis

Authors:

Adamyan L.V., Burgova E.N., Serezhenkov V.A., Sonova M.M., Tikhonova E.S., Laskevich A.V., Shamugia N.M., Vanin A.F.

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Journal: Russian Journal of Human Reproduction. 2012;(3): 7‑10

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THE ALTERATION OF LACTOFERRIN ACTIVE CENTER STRUCTURE IN PERITONEAL LIQUID OF PATIENTS WITH ENDOMETRIOSIS
THE ALTERATION OF LACTOFERRIN ACTIVE CENTER STRUCTURE IN PERITONEAL LIQUID OF PATIENTS WITH ENDOMETRIOSIS

To cite this article:

Adamyan LV, Burgova EN, Serezhenkov VA, et al. . The alteration of lactoferrin active center structure in peritoneal liquid of patients with endometriosis. Russian Journal of Human Reproduction. 2012;(3):7‑10. (In Russ.)

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Alterated EPR signal of Fe 3+-lactoferrin was recorded in peritoneal fluid in patients with genital endometriosis. The intensity of the EPR signal showed that concentration of Fe 3+- lactoferrin was lower if compare with patients with other gynecologic pathology.

Keywords:

endometriosis
lactoferrin
EPR

Authors:

Adamyan L.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Burgova E.N.

Institut khimicheskoĭ fiziki im. N.I. Semenova RAN, Moskva

Serezhenkov V.A.

Institut khimicheskoĭ fiziki im. N.I. Semenova RAN, Moskva

Sonova M.M.

Kafedra reproduktivnoĭ meditsiny i khirurgii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta

Tikhonova E.S.

Kafedra reproduktivnoĭ meditsiny i khirurgii fakul'teta poslediplomnogo obrazovaniia Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta

Laskevich A.V.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Shamugia N.M.

Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia

Vanin A.F.

Semenov institute of chemical physics of the Russian academy of sciences, Moscow, Russia;
Institute for regenerative medicine, Sechenov First Moscow State Medical University, Moscow, Russia

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References:

  1. Arnold R.R., Russell J.E., Champion W.J., Brewer M., Gauthier J.J. Bactericidal activity of human lactoferrin: differentiation from the stasis of iron deprivation. Infect Immun 1982; 35: 792-799.
  2. Elass-Rochard E., Roseanu A., Legrand D. et al. Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide. Biochem J 1995; 312: 839-845.
  3. Kuipers M.E., Heegsma J., Bakker H.L. et al. Design and fungicidal activity of mucoadhesive lactoferrin tablets for the treatment of oropharyngeal candidosis. Drug Deliv 2002; 9: 31-38.
  4. Omata Y., Satake M., Maeda R., Saito A. et al. Reduction of infectivity of Toxoplasma gondii and Eimeria stiedai sporozoites by treatment with bovine lactoferricin. J Vet Med Sci 2001; 63: 187-190.
  5. Brock J.H. The physiology of lactoferrin. Biochem Cell Biol 2002; 80: 1-6.
  6. Hayashida K., Takeuchi T., Shimizu H., Ando K., Harada E. Lactoferrin enhances opioid-mediated analgesia via nitric oxide in the spinal cord. Am J Physiol Regul Integr Comp Physiol 2003; 285: R306-R312.
  7. Hayashida K., Takeuchi T., Ozaki T., Shimizu H., Ando K. et al. Bovine lactoferrin has a nitric oxide-dependent hypotensive effect in rats. Am J Physiol Regul Integr Comp Physiol 2004; 286: R359-R365.
  8. Adamyan L.V., Kulakov V.I. Endometriozy. Rukovodstvo dlya vrachei. M: Meditsina 1998; 320.
  9. Adamyan L.V., Gasparyan S.A., Serezhenkov V.A., Vanin A.F., Burgova E.N. Narushenie svyazyvaniya zheleza pri endometrioze. Akush i ginekol 2003; 6: 24-26.
  10. Haider R.C. Nature of nontransferrin-bound iron. Eur J Clin Inv 2002; 32: Suppl 1: 50-54.
  11. Adamyan L.V., Spitsyn V.A., Andreeva E.N. Geneticheskie aspekty ginekologicheskikh zabolevanii. M: Meditsina: Antidor 1999; 63.
  12. Teng C.T., Beard C., Gladwell W. Differential expression and estrogen response of lactoferrin gene in the female reproductive tract of mouse, rat and hamster. Biol Reprod 2002; 67: 1439-1449.
  13. Pinkowitz R.A., Aisen P. Zero-Field Splittings of Iron Complexes of Transferrins. J Biol Chem 1972; 247: 7830-7834.
  14. Sandrini S.M., Shergill R., Woodward J. et al. Elucidation of the Mechanism by Which Catecholamine Stress Hormones Liberate Iron from the Innate Immune Defense Proteins Transferrin and Lactoferrin. J Bacteriol 2010; 192: 587-594.
  15. Gupta S., Agarwal A., Krajcir N., Alvarez J.G. Role of oxidative stress in endometriosis. Reprod BioMed Online 2006;13: 1: 126-134.
  16. Wang Y., Sharma R.K., Falcone T. et al. Importance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility. Fertil Steril 1997; 68: 826-830.
  17. Bailey M.T., Coe C.L. Endometriosis is associated with an altered profile of intestinal microflora in female rhesus monkeys. Human Reprod 2002; 17: 7: 1704-1708.
  18. An Q., Radcliffe G., Vassallo R. et al. Infection with a Plasmid-Free Variant Chlamydia Related to Chlamydia trachomatis Identified by Using Multiple Assays for Nucleic Acid Detection. J Clin Microbiol 1992; 30: 11: 2814-2821.
  19. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002; 415: 389-395.
  20. He Q.Y., Mason A.B., Woodworth R. et al. Mutations at nonliganding residues Tyr-85 and Glu-83 in the N-lobe of human serum transferrin. J Biol Chem 1998; 273: 27: 17018-17024.
  21. Zak O., Aisen P. Iron release from Tf, its C-lobe, and their complexes with Tf receptor: Presence of N-lobe accelerates release from C-lobe at endosomal pH. Biochemistry 2003; 42: 12330-12334.
  22. Mason A.B., Halbrooks P.J., James N.G. et al. Mutational Analysis of C-Lobe Ligands of Human Serum Transferrin: Insights into the Mechanism of Iron Release. Biochemistry 2005; 44: 8013-8021.
  23. Legrand D., Elass E., Carpentier M., Mazurier J. Lactoferrin: a modulator of immune and inflammatory responses. Cell Mol Life Sci 2005; 62: 2549-2559.
  24. Carmichael A.J., Steel-Goodwin L., Gray B., Arroyo C.M. Nitric oxide interaction with lactoferrin and its production by macrophage cells studied by EPR and spin trapping. Free Rad Res Comms 1993; 19: Suppl S201-S209.
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