The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Prohoda E.E.

Institute of Plastic Surgery and Cosmetology

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Stupin V.A.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Silina E.V.

Sechenov First Moscow State Medical University (Sechenov University)

3D composite tissue-engineering scaffolds as a donor material in reconstructive surgery of soft tissues: characteristics and current state of the problem

Authors:

Prohoda E.E., Manturova N.E., Stupin V.A., Silina E.V.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2025;(4): 97‑109

DOI: 10.17116/plast.hirurgia202504197

Read: 744 times

Download PDF (RU)
Download PDF
Contact the author
Table of contents

3D COMPOSITE TISSUE-ENGINEERING SCAFFOLDS AS A DONOR MATERIAL IN RECONSTRUCTIVE SURGERY OF SOFT TISSUES: CHARACTERISTICS AND CURRENT STATE OF THE PROBLEM
3D COMPOSITE TISSUE-ENGINEERING SCAFFOLDS AS A DONOR MATERIAL IN RECONSTRUCTIVE SURGERY OF SOFT TISSUES: CHARACTERISTICS AND CURRENT STATE OF THE PROBLEM

To cite this article:

Prohoda EE, Manturova NE, Stupin VA, Silina EV. 3D composite tissue-engineering scaffolds as a donor material in reconstructive surgery of soft tissues: characteristics and current state of the problem. Plastic Surgery and Aesthetic Medicine. 2025;(4):97‑109. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia202504197

Подписка 2026 Пластическая хирургия и эстетическая медицина (Plastic Surgery and Aesthetic Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Perspectives for educational programs on plastic surgery in the era of digi­tal technologies. Plastic Surgery and Aesthetic Medi­cine. 2025;(2):5-10
Septum orbi­tale as a key element in lower blepharoplasty: evolution from classic to tissue-sparing techniques. Plastic Surgery and Aesthetic Medi­cine. 2025;(2-2):96-102
Inte­rdisciplinary consensus: the tandem of surgeon and cosmetologist. Inte­rdisciplinary approach to the mana­gement and reha­bilitation of aesthetic patients. Plastic Surgery and Aesthetic Medi­cine. 2025;(3-2):56-63
Aesthetic analysis of the face in modern plastic surgery. Plastic Surgery and Aesthetic Medi­cine. 2025;(3-2):64-70
Beautiful rela­tionship between art and medi­cine: from clay mode­ling to auri­cular cartilage mode­ling. Plastic Surgery and Aesthetic Medi­cine. 2025;(3-2):71-77
Trunk muscles for flap reco­nstruction in plastic surgeries: a narrative review. Plastic Surgery and Aesthetic Medi­cine. 2025;(3-2):110-118
Implantation and transplantation mate­rials in plastic closure of nasal septum perforation (literature review). Russian Bulletin of Otorhinolaryngology. 2025;(2):55-62
Comprehensive asse­ssment of local hemo­dynamics and combined treatment of complicated form of infa­ntile hema­ngioma of the upper lip. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;(2):38-45
The rele­vance of changing the algo­rithm of commission fore­nsic examinations in aesthetic plastic surgery. Fore­nsic Medi­cal Expe­rtise. 2026;(1):5-10
Abstract:

Tissue engineering and regenerative medicine are emerging areas of medical science. They are actively used in clinical practice including practical and scientific fields of plastic surgery. Among these products are scaffold-based devices. These technologies are currently being studied as tissue matrices, advanced dressings and tools for delivering drugs and bioactive molecules (scaffolds functionalized to address clinical needs). A key scientific challenge is extreme heterogeneity of approaches to producing finished products and, consequently, to solving complex logistical problems. Potential for modern technologies customized for various tasks and multidisciplinary approach underpin the relevance of this review. This review presents evidence base of current research trends, perspective approaches to scaffold functionalization, and, consequently, development vectors in scaffold technologies.

Keywords:

plastic surgery
biotechnology
tissue engineering
scaffold
tissue matrix

Authors:

Prohoda E.E.

Institute of Plastic Surgery and Cosmetology

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Stupin V.A.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Silina E.V.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

30.10.2024

Accepted:

06.02.2024

Close metadata

References:

  1. Verbo EV, Manturova NE, Orlova YuM. Development of facial reconstructive surgery in the context of global historical aspect of this specialty. Plastic Surgery and Aesthetic Medicine. 2021;(1):94-105. (In Russ., In Engl.). https://doi.org/10.17116/plast.hirurgia202101194
  2. Macadam SA, Lennox PA. Acellular dermal matrices: Use in reconstructive and aesthetic breast surgery. The Canadian Journal of Plastic Surgery. 2012;20(2):75-89.  https://doi.org/10.1177%2F229255031202000201
  3. Chan BP, Leong KW. Scaffolding in tissue engineering: general approaches and tissue-specific considerations. European Spine Journal. 2008;17(S4): 467-479.  https://doi.org/10.1007/s00586-008-0745-3
  4. Zaszczyńska A, Moczulska-Heljak M, Gradys A, Sajkiewicz P. Advances in 3D Printing for Tissue Engineering. Materials. 2021;14(12):3149. https://doi.org/10.3390/ma14123149
  5. Arun Arjunan, Baroutaji A, Robinson J, Wang C. Tissue Engineering Concept. Elsevier eBooks. Published online January 01, 2022:103-112.  https://doi.org/10.1016/b978-0-12-815732-9.00120-0
  6. Shyam R, Reddy LVK, Palaniappan A. Fabrication and Characterization Techniques of In Vitro 3D Tissue Models. International Journal of Molecular Sciences. 2023;24(3):1912. https://doi.org/10.3390/ijms24031912
  7. Safinsha S, Mubarak Ali M. Composite scaffolds in tissue engineering. Materials Today: Proceedings. 2020;24:2318-2329. https://doi.org/10.1016/j.matpr.2020.03.761
  8. Guo B, Lei B, Li P, Ma PX. Functionalized scaffolds to enhance tissue regeneration. Regenerative Biomaterials. 2015;2(1):47-57.  https://doi.org/10.1093/rb/rbu016
  9. Mazzoni E, Iaquinta MR, Lanzillotti C, Mazziotta C, Maritati M, Montesi M, Sprio S, Tampieri A, Tognon M, Martini F. Bioactive Materials for Soft Tissue Repair. Frontiers in Bioengineering and Biotechnology. 2021 Feb 19; 9:613787. PMID: 33681157; PMCID: PMC7933465. https://doi.org/10.3389/fbioe.2021.613787
  10. Järbrink K, Ni G, Sönnergren H, Schmidtchen A, Pang C, Bajpai R, Car J. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. Systematic Reviews. 2016 Sept 08;5(1):152. PMID: 27609108; PMCID: PMC5017042. https://doi.org/10.1186/s13643-016-0329-y
  11. Zhan H, Löwik DWPM. A Hybrid Peptide Amphiphile Fiber PEG Hydrogel Matrix for 3D Cell Culture. Advanced Functional Materials. 2019;29(16): 1808505. https://doi.org/10.1002/adfm.201808505
  12. Hewitt E, Mros S, Mcconnell M, Cabral J, Ali A. Melt-electrowriting with novel milk protein/PCL biomaterials for skin regeneration. Biomedical Materials. Published online July 18, 2019. https://doi.org/10.1088/1748-605x/ab3344
  13. Ilhan E, Cesur S, Guler E, Topal F, Albayrak D, Guncu MM, Cam ME, Taskin T, Sasmazel HT, Aksu B, Oktar FN, Gunduz O. Development of Satureja cuneifolia-loaded sodium alginate/polyethylene glycol scaffolds produced by 3D-printing technology as a diabetic wound dressing material. International Journal of Biological Macromolecules. 2020 Oct 15;161:1040-1054. Epub 2020 June 13. PMID: 32544577. https://doi.org/10.1016/j.ijbiomac.2020.06.086
  14. Zehra M, Mehmood A, Yar M, Shahzadi L, Riazuddin S. Development of NSAID‐loaded nano‐composite scaffolds for skin tissue engineering applications. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2020;108(8):3064-3075. https://doi.org/10.1002/jbm.b.34634
  15. Afghah F, Ullah M, Seyyed Monfared Zanjani J, Akkus Sut P, Sen O, Emanet M, Saner Okan B, Culha M, Menceloglu Y, Yildiz M, Koc B. 3D printing of silver-doped polycaprolactone-poly(propylene succinate) composite scaffolds for skin tissue engineering. Biomedical Materials (Bristol, England). 2020 Apr 15;15(3):035015. PMID: 32032966. https://doi.org/10.1088/1748-605X/ab7417
  16. He Y, Hou Z, Wang J, Wang Z, Li X, Liu J, XiaolinYang, Liang Q, Zhao J. Assessment of biological properties of recombinant collagen-hyaluronic acid composite scaffolds. International Journal of Biological Macromolecules. 2020 Apr 15;149:1275-1284. Epub 2020 Feb 05. PMID: 32035148. https://doi.org/10.1016/j.ijbiomac.2020.02.023
  17. Radwan-Pragłowska J, Janus Ł, Piątkowski M, Bogdał D, Matýsek D. Hybrid Bilayer PLA/Chitosan Nanofibrous Scaffolds Doped with ZnO, Fe3O4, and Au Nanoparticles with Bioactive Properties for Skin Tissue Engineering. Polymers. 2020;12(1):159.  https://doi.org/10.3390/polym12010159
  18. Soubhagya AS, Balagangadharan K, Selvamurugan N, Sathya Seeli D, Prabaharan M. Preparation and characterization of chitosan/carboxymethyl pullulan/bioglass composite films for wound healing. Journal of Biomaterials Applications. 2021;36(7):1151-1163. https://doi.org/10.1177/08853282211050161
  19. Entekhabi E, Haghbin Nazarpak M, Shafieian M, Mohammadi H, Firouzi M, Hassannejad Z. Fabrication and in vitro evaluation of 3D composite scaffold based on collagen/hyaluronic acid sponge and electrospun polycaprolactone nanofibers for peripheral nerve regeneration. Journal of Biomedical Materials Research — Part A. 2021;109(3):300-312.  https://doi.org/10.1002/jbm.a.37023
  20. Merk M, Chirikian O, Adlhart C. 3D PCL/Gelatin/Genipin Nanofiber Sponge as Scaffold for Regenerative Medicine. Materials. 2021;14(8):2006. https://doi.org/10.3390/ma14082006
  21. Allbritton‐King JD, Kimicata M, Fisher JP. Incorporating a structural extracellular matrix gradient into a porcine urinary bladder matrix‐based hydrogel dermal scaffold. Journal of Biomedical Materials Research — Part A. 2021;109(10):1893-1904. Epub 2021 Apr 02. PMID: 33797180. https://doi.org/10.1002/jbm.a.37181
  22. Rafie M, Meshkini A. Tailoring the proliferation of fibroblast cells by multiresponsive and thermosensitive stem cells composite F127 hydrogel containing folic acid.MgO:ZnO/chitosan hybrid microparticles for skin regeneration. European Journal of Pharmaceutical Sciences. 2021;167:106031. Epub 2021 Oct 01. PMID: 34601068. https://doi.org/10.1016/j.ejps.2021.106031
  23. Du D, Liu Z, Niu W, Weng D, Lim TC, Kurisawa M, Spector M. An Injectable Multifunctional Dual-Phase Bead-Reinforced Gelatin Matrix Permissive of Mesenchymal Stem Cell Infiltration for Musculoskeletal Soft Tissue Repair. Advanced Healthcare Materials. 2021 Sept;10(18):e2100626. Epub 2021 July 14. PMID: 34263563. https://doi.org/10.1002/adhm.202100626
  24. Martin A, Nyman JN, Reinholdt R, Cai J, Schaedel AL, van der Plas MJA, Malmsten M, Rades T, Heinz A. In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels. Nanomaterials (Basel). 2022 Jul 16;12(14):2437. PMID: 35889661; PMCID: PMC9318765. https://doi.org/10.3390/nano12142437
  25. Giubilini A, Messori M, Bondioli F, Minetola P, Iuliano L, Nyström G, Maniura-Weber K, Rottmar M, Siqueira G. 3D-Printed Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)-Cellulose-Based Scaffolds for Biomedical Applications. Biomacromolecules. 2023 Sept 11;24(9):3961-3971. Epub 2023 Aug 17. PMID: 37589321; PMCID: PMC10498448. https://doi.org/10.1021/acs.biomac.3c00263
  26. O’Shea DG, Hodgkinson T, Curtin CM, O’Brien FJ. An injectable and 3D printable pro-chondrogenic hyaluronic acid and collagen type II composite hydrogel for the repair of articular cartilage defects. Biofabrication. 2023 Oct 27; 16(1). PMID: 37852239. https://doi.org/10.1088/1758-5090/ad047a
  27. Lutzweiler G, Ndreu Halili A, Engin Vrana N. The Overview of Porous, Bioactive Scaffolds as Instructive Biomaterials for Tissue Regeneration and Their Clinical Translation. Pharmaceutics. 2020;12(7):602.  https://doi.org/10.3390/pharmaceutics12070602
  28. Loh QL, Choong C. Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size. Tissue Engineering Part B: Reviews. 2013;19(6):485-502.  https://doi.org/10.1089/ten.teb.2012.0437
  29. Zhang J, Li J, Jia G, et al. Improving osteogenesis of PLGA/HA porous scaffolds based on dual delivery of BMP-2 and IGF-1 via a polydopamine coating. RSC Advances. 2017;7(89):56732-56742. https://doi.org/10.1039/c7ra12062a
  30. Thangavel M, Elsen Selvam R. Review of Physical, Mechanical, and Biological Characteristics of 3D-Printed Bioceramic Scaffolds for Bone Tissue Engineering Applications. ACS Biomaterials Science & Engineering. 2022; 8(12):5060-5093. PMID: 36415173. https://doi.org/10.1021/acsbiomaterials.2c00793
  31. Rahyussalim AJ, Kurniawati T, Aprilya D, Anggraini R, Ramahdita G, Whulanza Y. Toxicity and biocompatibility profile of 3D bone scaffold developed by Universitas Indonesia: A preliminary study. AIP Conference Proceedings. 2018 Feb 21;1817(1):020004. Published online January 01, 2017. https://doi.org/10.1063/1.4976756
  32. Wang W, Caetano G, Ambler W, et al. Enhancing the Hydrophilicity and Cell Attachment of 3D Printed PCL/Graphene Scaffolds for Bone Tissue Engineering. Materials. 2016;9(12):992.  https://doi.org/10.3390/ma9120992
  33. Zhang Z, Feng Y, Wang L, Liu D, Qin C, Shi Y. A review of preparation methods of porous skin tissue engineering scaffolds. Materials Today Communications. 2022;32:104109. https://doi.org/10.1016/j.mtcomm.2022.104109
  34. An J, Teoh JEM, Suntornnond R, Chua CK. Design and 3D Printing of Scaffolds and Tissues. Engineering. 2015;1(2):261-268.  https://doi.org/10.15302/j-eng-2015061
  35. Holt B, Tripathi A, Morgan J. Viscoelastic response of human skin to low magnitude physiologically relevant shear. Journal of Biomechanics. 2008; 41(12):2689-2695. https://doi.org/10.1016/j.jbiomech.2008.06.008
  36. Joodaki H, Panzer MB. Skin mechanical properties and modeling: A review. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2018;232(4):323-343.  https://doi.org/10.1177/0954411918759801
  37. Boeckel DG, Shinkai RSA, Grossi ML, Teixeira ER. In vitro evaluation of cytotoxicity of hyaluronic acid as an extracellular matrix on OFCOL II cells by the MTT assay. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology. 2014;117(6):e423-e428. https://doi.org/10.1016/j.oooo.2012.07.486
  38. Ming L, Zhipeng Y, Fei Y, Feng R, Jian W, Baoguo J, Yongqiang W, Peixun Z. Microfluidic-based screening of resveratrol and drug-loading PLA/Gelatine nano-scaffold for the repair of cartilage defect. Artificial Cells, Nanomedicine, and Biotechnology. 2018;46(Suppl 1):336-346. Epub 2018 Mar 26. PMID: 29575923. https://doi.org/10.1080/21691401.2017.1423498
  39. Shahriari-Khalaji M, Sattar M, Cao R, Zhu M. Angiogenesis, hemocompatibility and bactericidal effect of bioactive natural polymer-based bilayer adhesive skin substitute for infected burned wound healing. Bioactive Materials. 2023;29:177-195.  https://doi.org/10.1016/j.bioactmat.2023.07.008
  40. Chebotarev SV, Kalyuzhnaya LI, Khominets VV, Chernov VE, Frumkina AS, Zemlyanoy DA, Shaitor VM, Tovpeko DV, Malekov DA, Protasov OV. Regenerative effects of human umbilical cord hydrogel in the treatment of articular cartilage injuries. Clinical and Experimental Surgery. Petrovsky Journal. 2020;8(4):119-125. (In Russ.). https://doi.org/10.33029/2308-1198-2020-8-4-119-125
  41. Dong Y, Liu Z, Qi F, Jin L, Zhang L, Zhu N. Polyethylene-Glycol-Ornamented Small Intestinal Submucosa Biosponge for Skin Tissue Engineering. ACS Biomaterials Science & Engineering. 2019;5(5):2457-2465. https://doi.org/10.1021/acsbiomaterials.8b01592
  42. Koo MA, Hee Hong S, Hee Lee M, Kwon BJ, Mi Seon G, Sung Kim M, Kim D, Chang Nam K, Park JC. Effective stacking and transplantation of stem cell sheets using exogenous ROS-producing film for accelerated wound healing. Acta Biomaterialia. 2019 Sept 01;95:418-426. Epub 2019 Jan 16. PMID: 30660002. https://doi.org/10.1016/j.actbio.2019.01.019
  43. Xu P, Gao Q, Feng X, Lou L, Zhu T, Gao C, Ye J. A biomimetic tarso-conjunctival biphasic scaffold for eyelid reconstruction in vivo. Biomaterials Science. 2019 Aug 01;7(8):3373-3385. Epub 2019 June 24. PMID: 31233046. https://doi.org/10.1039/c9bm00431a
  44. Nilforoushzadeh MA, Khodadadi Yazdi M, Baradaran Ghavami S, Farokhimanesh S, Mohammadi Amirabad L, Zarrintaj P, Saeb MR, Hamblin MR, Zare M, Mozafari M. Mesenchymal Stem Cell Spheroids Embedded in an Injectable Thermosensitive Hydrogel: An In Situ Drug Formation Platform for Accelerated Wound Healing. ACS Biomaterials Science & Engineering. 2020 Sept 14;6(9):5096-5109. Epub 2020 Aug 27. PMID: 33455261. https://doi.org/10.1021/acsbiomaterials.0c00988
  45. Badhe RV, Godse A, Shinkar A, Kharat A, Patil V, Gupta A, Kheur S. Development and Characterization of Conducting-Polymer-Based Hydrogel Dressing for Wound Healing. Turkish Journal of Pharmaceutical Sciences. 2021 Sept 01;18(4):483-491. PMID: 34496555; PMCID: PMC8430405. https://doi.org/10.4274/tjps.galenos.2020.44452
  46. Gao D, Wang Z, Wu Z, Guo M, Wang Y, Gao Z, Zhang P, Ito Y. 3D-printing of solvent exchange deposition modeling (SEDM) for a bilayered flexible skin substitute of poly (lactide-co-glycolide) with bioorthogonally engineered EGF. Materials Science & Engineering C, Materials for Biological Applications. 2020 Jul;112:110942. Epub 2020 Apr 08. PMID: 32409088. https://doi.org/10.1016/j.msec.2020.110942
  47. Hong Y, Liu N, Zhou R, Zhao X, Han Y, Xia F, Cheng J, Duan M, Qian Q, Wang X, Cai W, Zreiqat H, Feng D, Xu J, Cui D. Combination Therapy Using Kartogenin-Based Chondrogenesis and Complex Polymer Scaffold for Cartilage Defect Regeneration. ACS Biomaterials Science & Engineering. 2020 Nov 09;6(11):6276-6284. Epub 2020 Oct 13. PMID: 33449656. https://doi.org/10.1021/acsbiomaterials.0c00724
  48. Svistushkin VM, Timashev PS, Shekhter AB, Zolotova AV, Mokoyan ZhT, Svistushkin MV. Experimental evidence for regenerative treatment of chronic tympanic membrane perforation. Russian Bulletin of Otorhinolaryngology. 2020;85(6):23-26. (In Russ.). https://doi.org/10.17116/otorino20208506123
  49. Chang B, Cornett A, Nourmohammadi Z, Law J, Weld B, Crotts SJ, Hollister SJ, Lombaert IMA, Zopf DA. Hybrid Three-Dimensional-Printed Ear Tissue Scaffold With Autologous Cartilage Mitigates Soft Tissue Complications. The Laryngoscope. 2021 May;131(5):1008-1015. Epub 2020 Oct 06. PMID: 33022112; PMCID: PMC8021596. https://doi.org/10.1002/lary.29114
  50. Chhabra R, Vaibhavi Peshattiwar, Pant T, et al. In Vivo Studies of 3D Starch-Gelatin Scaffolds for Full-Thickness Wound Healing. ACS Applied Bio Materials. 2020;3(5):2920-2929. https://doi.org/10.1021/acsabm.9b01139
  51. Siebert L, Luna-Cerón E, García-Rivera LE, Oh J, Jang J, Rosas-Gómez DA, Pérez-Gómez MD, Maschkowitz G, Fickenscher H, Oceguera-Cuevas D, Holguín-León CG, Byambaa B, Hussain MA, Enciso-Martinez E, Cho M, Lee Y, Sobahi N, Hasan A, Orgill DP, Mishra YK, Adelung R, Lee E, Shin SR. Light-controlled growth factors release on tetrapodal ZnO-incorporated 3D-printed hydrogels for developing smart wound scaffold. Advanced Functional Materials. 2021 May 26;31(22):2007555. Epub 2021 Feb 19. PMID: 36213489; PMCID: PMC9536771. https://doi.org/10.1002/adfm.202007555
  52. Dong W, Song Z, Liu S, Yu P, Shen Z, Yang J, Yang D, Hu Q, Zhang H, Gu Y. Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects via HIF-1α/VEGF Pathway. Frontiers in Bioengineering and Biotechnology. 2021 July 07;9:676409. PMID: 34307320; PMCID: PMC8293919. https://doi.org/10.3389/fbioe.2021.676409
  53. Zhang K, Wang Y, Wei Q, Li X, Guo Y, Zhang S. Design and Fabrication of Sodium Alginate/Carboxymethyl Cellulose Sodium Blend Hydrogel for Artificial Skin. Gels. 2021;7(3):115.  https://doi.org/10.3390/gels7030115
  54. Chiang CE, Fang YQ, Ho CT, Assunção M, Lin SJ, Wang YC, Blocki A, Huang CC. Bioactive Decellularized Extracellular Matrix Derived from 3D Stem Cell Spheroids under Macromolecular Crowding Serves as a Scaffold for Tissue Engineering. Advanced Healthcare Materials. 2021 June;10(11): e2100024. Epub 2021 Apr 22. PMID: 33890420. https://doi.org/10.1002/adhm.202100024
  55. Zhang D, Fu Q, Fu H, Zeng J, Jia L, Chen M. 3D-bioprinted human lipoaspirate-derived cell-laden skin constructs for healing of full-thickness skin defects. International Journal of Bioprinting. 2023;9(4):718.  https://doi.org/10.18063/ijb.718
  56. Bashiri Z, Rajabi Fomeshi M, Ghasemi Hamidabadi H, Jafari D, Alizadeh S, Nazm Bojnordi M, Orive G, Dolatshahi-Pirouz A, Zahiri M, Reis RL, Kundu SC, Gholipourmalekabadi M. 3D-printed placental-derived bioinks for skin tissue regeneration with improved angiogenesis and wound healing properties. Materials Today Bio. 2023 May 20;20:100666. Erratum in: Materials Today Bio. 2024 Sept 30;29:101278. PMID: 37273796; PMCID: PMC10239019. https://doi.org/10.1016/j.mtbio.2024.101278
  57. Lin Y, Liu E, Lin Y, Hooi Yee Ng, Lee J, Hsu TT. The Synergistic Effect of Electrical Stimulation and Dermal Fibroblast Cells-Laden 3D Conductive Hydrogel for Full-Thickness Wound Healing. International Journal of Molecular Sciences. 2023;24(14):11698. https://doi.org/10.3390/ijms241411698
  58. Zhang G, Zhang Z, Cao G, Jin Q, Xu L, Li J, Liu Z, Xu C, Le Y, Fu Y, Ju J, Li B, Hou R. Engineered dermis loaded with confining forces promotes full-thickness wound healing by enhancing vascularisation and epithelialisation. Acta Biomaterialia. 2023 Oct 15;170:464-478. Epub 2023 Aug 30. PMID: 37657662. https://doi.org/10.1016/j.actbio.2023.08.049
  59. Khoshmaram K, Yazdian F, Pazhouhnia Z, Lotfibakhshaiesh N. Preparation and characterization of 3D bioprinted gelatin methacrylate hydrogel incorporated with curcumin loaded chitosan nanoparticles for in vivo wound healing application. Biomaterials Advances. 2024;156:213677. https://doi.org/10.1016/j.bioadv.2023.213677
  60. Wang S, Chen H, Huang J, Shen S, Tang Z, Tan X, Lei D, Zhou G. Gelatin-modified 3D printed PGS elastic hierarchical porous scaffold for cartilage regeneration. APL Bioengineering. 2023 Aug 04;7(3):036105. PMID: 37547670; PMCID: PMC10404141. https://doi.org/10.1063/5.0152151
  61. Song M, Liu Y, Hui L. Preparation and characterization of acellular adipose tissue matrix using a combination of physical and chemical treatments. Molecular Medicine Reports. 2018;17(1):138-146.  https://doi.org/10.3892/mmr.2017.7857
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.