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Golubev P.V.

Herzen Moscow Research Cancer Institute

Bolotina L.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia

Gevorkov A.R.

P.A. Herzen Moscow Oncology Research Institute - Branch of the National Medical Radiology Research Center of the Ministry of Health of the Russia

Deshkina T.I.

P.A. Herzen Moscow Oncology Research Institute - Branch of the National Medical Radiology Research Center of the Ministry of Health of the Russia

A current view on the possibility of treatment volume de-escalation in HPV-associated oropharyngeal squamous cell carcinoma

Authors:

Golubev P.V., Bolotina L.V., Gevorkov A.R., Deshkina T.I.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2021;10(3): 47‑53

DOI: 10.17116/onkolog20211003147

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Table of contents

A CURRENT VIEW ON THE POSSIBILITY OF TREATMENT VOLUME DE-ESCALATION IN HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
A CURRENT VIEW ON THE POSSIBILITY OF TREATMENT VOLUME DE-ESCALATION IN HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA

To cite this article:

Golubev PV, Bolotina LV, Gevorkov AR, Deshkina TI. A current view on the possibility of treatment volume de-escalation in HPV-associated oropharyngeal squamous cell carcinoma. P.A. Herzen Journal of Oncology. 2021;10(3):47‑53. (In Russ.)
https://doi.org/10.17116/onkolog20211003147

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
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Abstract:

Papillomavirus infection-associated oropharyngeal squamous cell carcinoma is an urgent problem of modern oncology. Despite its visual localization, this nosological entity is characterized by a high degree of neglect (in only 16.1% of patients, this disease is detected in early stages (I—II), which leads to unsatisfactory long-term treatment results and necessitates aggressive approaches to therapy. The review presents the current views of Russian and foreign experts on the prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinoma and the possibility of de-escalation of a treatment regimen.

Keywords:

squamous cell carcinoma
head and neck cancer
oropharyngeal cancer
human papillomavirus

Authors:

Golubev P.V.

Herzen Moscow Research Cancer Institute

Bolotina L.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia

Gevorkov A.R.

P.A. Herzen Moscow Oncology Research Institute - Branch of the National Medical Radiology Research Center of the Ministry of Health of the Russia

Deshkina T.I.

P.A. Herzen Moscow Oncology Research Institute - Branch of the National Medical Radiology Research Center of the Ministry of Health of the Russia

Received:

22.11.2020

Accepted:

29.01.2021

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