Current approaches to treating patients with colorectal lung metastases

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The review provides information on main approaches to treating patients with colorectal lung metastases. The analysis of prognostic factors is shown to create the basis for a differentiated approach to determining the indications for removal of lung metastases. To date, the surgical stage remains the mainstay of therapy in patients with colorectal lung metastases. The proven efficiency of drug therapy involves a compulsory combination of these two methods. The authors present their own results of surgical treatment in 112 patients with colorectal lung metastases.

Keywords:

colorectal cancer

prognostic factors

lung metastases

surgical treatment for lung metastases

Authors:

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Pikin O.V.

FGBU "MNIOI im. P.A. Gertsena" Minzdrava Rossii

Kolbanov K.I.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ

Glushko V.A.

P.A. Gertsen Moscow Research Cancer Institute, Russian Ministry of Health

Vursol D.A.

P.A. Hertzen Moscow Research Institute of Oncology, Russian Federation, Moscow

Aleksandrov O.A.

Herzen Moscow Scientific Oncological Institute — the branch of the National Medical Research Center for Radiology of Healthcare Ministry of the Russia, Moscow, Russia

List of references:

Treasure T, Russell C, Macbeth F. Re-launch of PulMiCC trial to discover the true effect of pulmonary metastasectomy on survival in advanced colorectal cancer. BMJ. 2015;351(12):h6045. https://doi.org/10.1136/bmj.h6045
Watanabe K, Saito N, Sugito M, Ito M, Kobayashi A, Nishizawa Y. Incidence and predictive factors for pulmonary metastases after curative resection of colon cancer. Ann Surg Oncol. 2012;20(4):1374-80. https://doi.org/10.1245/s10434-012-2747-y
Tan K, Lopes Jr. G, Sim R. How uncommon are isolated lung metastases in colorectal cancer? A review from database of 754 patients over 4 years. J Gastrointest Surg. 2008;13(4):642-648. https://doi.org/10.1007/s11605-008-0757-7
Wangensteen OH, Lewis FJ, Arhelger SW, et al. An interim report upon the second look procedure for cancer of the stomach, colon and rectum and for limited intraperitoneal carcinonosis. Surg Gynecol Obstet. 1954;99:257-267.
Villeneuve P, Sundaresan R. Surgical management of colorectal lung metastasis. Clin Colon Rectal Surg. 2009;22(04):233-241. https://doi.org/10.1055/s-0029-1242463
McCormack P, Attiyeh F. Resected pulmonary metastases from colorectal cancer. Dis Colon Rectum. 1979;22(8):553-556. https://doi.org/10.1007/bf02587003
Mansel J, Zinsmeister A, Pairolero P, Jett J. Pulmonary resection of metastatic colorectal adenocarcinoma. Chest. 1986;89(1):109-112. https://doi.org/10.1378/chest.89.1.109
McAfee M, Allen M, Trastek V, Ilstrup D, Deschamps C, Pairolero P. Colorectal lung metastases: results of surgical excision. Ann Thorac Surg. 1992;53(5):780-786. https://doi.org/10.1016/0003-4975(92)91435-c
Scheele J, Altendorf-Hofmann A, Stangl R, Gall F. Pulmonary resection for metastatic colon and upper rectum cancer. Dis Colon Rectum. 1990;33(9):745-752. https://doi.org/10.1007/bf02052319
Rusch V. Pulmonary metastasectomy. Chest. 1995;107(6):322S-31S. https://doi.org/10.1378/chest.107.6_supplement.322s
Saito Y, Omiya H, Kohno K, et al. Pulmonary metastasectomy for 165 patients with colorectal carcinoma: a prognostic assessment. J Thorac Cardiovasc Surg. 2002;124(5):1007-1013. https://doi.org/10.1067/mtc.2002.125165
Pfannschmidt J, Muley T, Hoffmann H, Dienemann H. Prognostic factors and survival after complete resection of pulmonary metastases from colorectal carcinoma: Experiences in 167 patients. J Thorac Cardiovasc Surg. 2003;126(3):732-739.
Kanemitsu Y, Kato T, Hirai T, Yasui K. Preoperative probability model for predicting overall survival after resection of pulmonary metastases from colorectal cancer. Br J Surg. 2004;91(1):112-120. https://doi.org/10.1002/bjs.4370
Vogelsang H, Haas S, Hierholzer C, Berger U, Siewert J, Präuer H. Factors influencing survival after resection of pulmonary metastases from colorectal cancer. Br J Surg. 2004;91(8):1066-1071. https://doi.org/10.1002/bjs.4602
Lizasa T, Suzuki M, Yoshida S, et al. Prediction of prognosis and surgical indications for pulmonary metastasectomy from colorectal cancer. Ann Thorac Surg. 2006;82(1):254-260. https://doi.org/10.1016/j.athoracsur.2006.02.027.
Pfannschmidt J, Dienemann H, Hoffmann H. Surgical resection of pulmonary metastases from colorectal cancer: a systematic review of published series. Ann Thorac Surg. 2007;84(1):324-338. https://doi.org/10.1016/j.athoracsur.2007.02.093
Chen F, Hanaoka N, Sato K, et al. Prognostic factors of pulmonary metastasectomy for colorectal carcinomas. World J Surg. 2009;33(3):505-511. https://doi.org/10.1007/s00268-008-9875-3
Mori M. Surgical resection of pulmonary metastases from colorectal adenocarcinoma. Arch Surg. 1991;126(10):1297. https://doi.org/10.1001/archsurg.1991.01410340139020
Borasio P, Gisabella M, Billé A, et al. Role of surgical resection in colorectal lung metastases: analysis of 137 patients. Int J Colorectal Dis. 2010;26(2):183-190. https://doi.org/10.1007/s00384-010-1075-6
Hamaji M, Cassivi SD, Shen KR, Allen MS, Nichols FC, Deschamps C, Wigle DA. Is lymph node dissection required in pulmonary metastasectomy for colorectal adenocarcinoma? Ann Thorac Surg. 2012;94(6):1796-1800. https://doi.org/10.1016/j.athoracsur.2012.04.049
Lida T, Nomori H, Shiba M, Nakajima J, Okumura S, Horio H, et al. Prognostic factors after pulmonary metastasectomy for colorectal cancer and rationale for determining surgical indications: a retrospective analysis. Ann Surg. 2013;257(6):1059-1064. https://doi.org/10.1097/sla.0b013e31826eda3b
Gonzalez M, Poncet A, Combescure C, Robert J, Ris H, Gervaz P. Risk factors for survival after lung metastasectomy in colorectal cancer patients: a systematic review and meta-analysis. Ann Surg Oncol. 2012;20(2):572-579. https://doi.org/10.1245/s10434-01
Cho JH, Kim S, Namgung M, Choi YS, Kim HK, Zo JI, Shim YM, Kim J. The prognostic importance of the number of metastases in pulmonary metastasectomy of colorectal cancer. World J Surg Oncol. 2015;13:222. https://doi.org/10.1186/s12957-015-0621-7
Åberg T, Treasure T. Analysis of pulmonary metastasis as an indication for operation: an evidence-based approach. Eur J Cardiothorac Surg. 2016;50(5):792-798. https://doi.org/10.1093/ejcts/ezw140
Utley M, Treasure T. Interpreting data from surgical follow-up studies: the role of modeling. J Thorac Oncol. 2010;5(6):S200-S202. https://doi.org/10.1097/jto.0b013e3181dd0a8d
Embún R, Fiorentino F, Treasure T, Rivas J, Molins L. Pulmonary metastasectomy in colorectal cancer: a prospective study of demography and clinical characteristics of 543 patients in the Spanish colorectal metastasectomy registry (GECMP-CCR). BMJ Open. 2013;3(5):pii:e002787.
Pfannschmidt J, Hoffmann H, Dienemann H. Reported outcome factors for pulmonary resection in metastatic colorectal cancer. J Thorac Oncol. 2010;5(6):S172-S178. https://doi.org/10.1097/jto.0b013e3181dca330
Cho JH, Hamaji M, Allen MS, Cassivi SD, Nichols FC 3^rd, Wigle D, Shen KR, Deschamps C. The prognosis of pulmonary metastasectomy depends on the location of the primary colorectal cancer. Ann Thorac Surg. 2014;98(4):1231-1237. https://doi.org/10.1016/j.athoracsur.2014.05.023
Cho S, Song I, Yang H, Jheon S. Prognostic factors of pulmonary metastasis from colorectal carcinoma. Interactive Cardiovasc Thorac Surg. 2013;17(2):303-307. https://doi.org/10.1093/icvts/ivt164
Welter S, Jacobs J, Krbek T, Poettgen C, Stamatis G. Prognostic impact of lymph node involvement in pulmonary metastases from colorectal cancer. Eur J Cardiothorac Surg. 2007;31(2):167-172. https://doi.org/10.1016/j.ejcts.2006.11.004
Shiono S, Matsutani N, Okumura S, et al. The prognostic impact of lymph-node dissection on lobectomy for pulmonary metastasis. Eur J Cardiothorac Surg. 2015;48(4):616-621. https://doi.org/10.1093/ejcts/ezu533
Bölükbas S, Sponholz S, Kudelin N, Eberlein M, Schirren J. Risk factors for lymph node metastases and prognosticators of survival in patients undergoing pulmonary metastasectomy for colorectal cancer. Ann Thorac Surg. 2014;97(6):1926-1932.
Szoke T, Kortner A, Neu R, et al. Is the mediastinal lymphadenectomy during pulmonary metastasectomy of colorectal cancer necessary? Interactive Cardiovasc Thorac Surg. 2010;10(5):694-698. https://doi.org/10.1510/icvts.2009.213173
Younes R, Abrao F, Gross J. Pulmonary metastasectomy for colorectal cancer: Long-term survival and prognostic factors. Int J Surg. 2013;11(3):244-248. https://doi.org/10.1016/j.ijsu.2013.01.003
Mineo T, Ambrogi V, Tonini G, et al. Long-term results after resection of simultaneous and sequential lung and liver metastases from colorectal carcinoma. J Am Coll Surg. 2003;197(3):386-391. https://doi.org/10.1016/s1072-7515(03)00387-9
Robinson B, Rice T, Strong S, Rybicki L, Blackstone E. Is resection of pulmonary and hepatic metastases warranted in patients with colorectal cancer? J Thorac Cardiovasc Surg. 1999;117(1):66-76. https://doi.org/10.1016/s0022-5223(99)70470-8
Tomimaru Y, Noura S, Ohue M, et al. Metastatic tumor doubling time is an independent predictor of intrapulmonary recurrence after pulmonary resection of solitary pulmonary metastasis from colorectal cancer. Dig Surg. 2008;25(3):220-225. https://doi.org/10.1159/000140693
Shiono S, Ishii G, Nagai K, et al. Histopathologic prognostic factors in resected colorectal lung metastases. Ann Thorac Surg. 2005;79(1):278-282. https://doi.org/10.1016/j.athoracsur.2004.06.096
Pastorino U, Veronesi G, Landoni C, et al. Fluorodeoxyglucose positron emission tomography improves preoperative staging of resectable lung metastasis. J Thorac Cardiovasc Surg. 2003;126(6):1906-1910. https://doi.org/10.1016/s0022-5223(03)002
Kaprin AD, Rubtsova NA, Trakhtenberg AKh, Ryabov AB, Pikin OV, Khalimon AI, Amiraliev AM, Leont’ev AV. Rol’ trekhmernogo komp’yuternogo modelirovaniya bronkhososudistykh struktur pri radikal’nykh sublobarnykh anatomicheskikh rezektsiyakh u patsientov s perifericheskimi novoobrazovaniyami legkikh. Luchevaya diagnostika i terapiya. 2016;3:33-39. (In Russ.) https://doi.org/10.22328/2079-5343-2016-3-33-3
Eguchi T, Takasuna K, Kitazawa A, Fukuzawa Y, Sakaue Y, Yoshida K, Matsubara M. Three-dimensional imaging navigation during a lung segmentectomy using an iPad. Eur J Cardiothorac Surg. 2012;41(4):893-897. https://doi.org/10.1093/ejcts/ezr127
Dennis J. Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm. Clin Cancer Res. 2005;11(10):3766-3772. https://doi.org/10.1158/1078-0432.ccr-04-2236
Hellman S, Weichselbaum R. Oligometastases. J Clin Oncol. 1995;13(1):8-10. https://doi.org/10.1200/jco.1995.13.1.8
NCCN Clinical Practice Guidelines in Oncology: colon cancer. 2013. Available at: https://www.tri-kobe.org/nccn/guideline/colorectal/english/colon.pdf
Poston G. Guideline Development Group. Colorectal cancer: the diagnosis and management of colorectal cancer. National Institute for Health Exellence; 2011. Available at: http:// guidance.nice.org.uk/CG131/Guidance/pdf/English
Chissov VI, Vashakmadze LA, Sidorov DV, Homyakov VM, Pikin OV. Tsitoreduktivnye operatsii pri metastaticheskom kolorektal’nom rake. Vestnik Moskovskogo onkologicheskogo obshchestva. 2004;2:3,4. (In Russ.)

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