The paper considers the capabilities of ultrasound study in the diagnosis and staging of pancreatic cancer (PC). Subjects and methods. The authors made a prospective analysis of the results of treatment in 56 patients with a morphologically verified pancreatic tumor, who had been treated at the P.A. Herzen Moscow Oncology Research Institute in 2011 to 2013. Results. The investigation covered 56 patients (13 men and 43 women) aged 18 to 78 years (mean age 60.6 years). The tumor was located in the head of the pancreas in 42 patients, in its body in 5 patients, and in its tail in 9. The mean tumor size was 38.5 mm. The least and most tumor sizes were 10 and 120 mm, respectively. The tumor was visualized in the ultrasound images of all the patients. Surgery had been previously performed in 21 (38%) patients. The accuracy of sonography in determining the involvement of the adjacent organs was 91.1%. The sensitivity, specificity, and accuracy in identifying vascular invasion were 88.9, 85.7, and 87.8%, respectively. Its sensitivity, accuracy, and specificity in determining the metastatic involvement of lymph nodes were 83.3, 72.7, and 78.8%, respectively. The accuracy of ultrasound study in revealing liver focal masses and liver metastases was 98.1 and 92.7%, respectively. Conclusion. Ultrasound study is a highly informative procedure for diagnosing and determining the extent of pancreatic tumors. The possible morphological verification of changes in both the pancreas and in the detection of distant metastases at low risk of complications is an important supplement for examining patients with pancreatic tumor involvement.