Personalized medicine for the diagnosis and prevention of arterial hypertension

Mansurova L.N.; Kireeva V.V.; Lepekhova S.A.; Alekseevskaya T.I.

doi:https://doi.org/10.17116/medtech20204204130

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Abstract:

The article is devoted to the diagnosis and prevention of arterial hypertension using the methods of personalized medicine. Considering significant economic consequences of complications of arterial hypertension, in particular, cardiovascular diseases, it is necessary to enhance clinical methods of diagnosis and prevention of this pathology. The concept of prevention of arterial hypertension has existed in our country for many years. The authors emphasize that preventive measures enshrined in legal acts and recommended for clinical practice in our country are usually addressed for patients with cardiovascular diseases and complications. The role of molecular genetic testing in predictive prevention of arterial hypertension is discussed. In case of genetic predisposition, preventive scheme can be determined according to a personalized approach. It should be noted that preventive measures in relation to cardiovascular diseases are currently initiated earlier (before organ damage) in modern conditions. According to foreign researchers, prevention of arterial hypertension in adults should be initiated even in prenatal period with correction of modified risk factors in mother. In addition, various foreign and national authors emphasize an importance of patient’s responsibility for own health. Subsequently, this aspect will be valuable to ensure higher adherence to prevention and treatment. However, it is often difficult to achieve adequate compliance due to impaired health-related quality of life. This problem may be resolved via the questionnaires on the quality of life and molecular genetic testing. Combination of these methods together with other modern diagnostic methods will create a personalized approach to prevention of hypertension in a particular patient.

Keywords:

arterial hypertension

health-related quality of life

genetic testing

prevention

Authors:

Mansurova L.N.

Irkutsk Research Center of Siberian Brunch of the Russian Academy of Science

Kireeva V.V.

Irkutsk Research Center of Siberian Brunch of the Russian Academy of Science

SPIN RSCI: 9534-2851
ORCID: 0000-0003-3696-9799

Lepekhova S.A.

Irkutsk Research Center of Siberian Brunch of the Russian Academy of Science

Alekseevskaya T.I.

Irkutsk State Medical University

Received:

17.06.2020

Accepted:

03.07.2020

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References:

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