This brief review presents scientific publications for the third quarter and early fourth quarter of 2025. The authors evaluated publications covering a wide range of topics. Some of the main events of this period were the new FDA protocol for «probabilistic studies» and active preparation for use by specialists, the completion of the largest metabolomic project UK Biobank, a new strategy for genome editing, and others. These topics have received extensive media coverage, highlighting the growing public attention to the development of medical genetics technologies and the need for further intensive work to accurately report on these topics.