Abstract Introduction. Performing a clinical blood test (hemogram) is an essential component of assessing the health of a newborn baby. However, the values of the hemogram parameters differ in venous and capillary blood and depend on the brand of hematology analyzer. Objectives — establishment of reference intervals of hemogram of capillary blood of children of the first days of life for the analyzer Sysmex XN-1000. Material and methods. The study used retrospective data from a clinical analysis of the blood of full-term infants transferred from the delivery room to the neonatal department of the obstetric observatory department who were not in the intensive care unit of this department and were discharged on the 3rd day of life without transferring to the neonatal department. 574 children (261 boys, 313 girls) met these criteria, 31 children were prematurely gestational. The median body weight of newborns taken in the study was 3410 g. The number of children taken at 1, 2 and 3 days was 289, 273 and 12 newborns, respectively. Blood sampling was carried out from the heel into MiniCollect tubes with K3 EDTA (Greiner Bio-One, Austria). Blood samples were examined on a XN-1000 hematology analyzer (Sysmex Corporation, Japan). The limits of the reference intervals were calculated in accordance with the recommendations of the Institute of Clinical and Laboratory Standards (C28-A3c, CLSI). A non-parametric method based on the bootstrap procedure (Bootstrap quantile) was used. For each indicator, the median was calculated, lower (2.5%) and upper (97.5%) limits of the reference interval (RI) with 90% confidence intervals. Statistical data processing was performed in the program Analyze-it. Additionally, the RI limits were calculated by an indirect method in the R program using the mixtools package. Results. The dynamics of changes in the clinical analysis of blood consistent with the previously described features of blood formation in newborns. At the same time, method-dependent RI limits were obtained for 28 hemogram indices of capillary blood. Confirmed a rapid decrease in the number of leukocytes during the first days of life. RIs calculated by the direct and indirect methods coincide quite well, which confirms the homogeneity of the reference sample.